Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Michelle C. LaPlaca"'
Autor:
Dmitry Leontyev, Alexis N. Pulliam, Xin Ma, David A. Gaul, Michelle C. LaPlaca, Facundo M. Fernández
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Traumatic brain injury (TBI) is a global public health problem with 50–60 million incidents per year, most of which are considered mild (mTBI) and many of these repetitive (rmTBI). Despite their massive implications, the pathologies of mTBI and rmT
Externí odkaz:
https://doaj.org/article/3b4bf857901244bca9a349fa7bb067a4
Autor:
Alexis N. Pulliam, Alyssa F. Pybus, David A. Gaul, Samuel G. Moore, Levi B. Wood, Facundo M. Fernández, Michelle C. LaPlaca
Publikováno v:
Metabolites, Vol 14, Iss 3, p 133 (2024)
Traumatic brain injury (TBI) is a significant source of disability in the United States and around the world and may lead to long-lasting cognitive deficits and a decreased quality of life for patients across injury severities. Following the primary
Externí odkaz:
https://doaj.org/article/aeea03b3b0b24d62b6e2747b295ee6b3
Autor:
Tamara R. Espinoza, Kristopher A Hendershot, Brian Liu, Andrea Knezevic, Breanne B. Jacobs, Russell K. Gore, Kevin M. Guskiewicz, Jeffery J. Bazarian, Shean E. Phelps, David W. Wright, Michelle C. LaPlaca
Publikováno v:
Neurotrauma Reports, Vol 2, Iss 1, Pp 232-244 (2021)
Mild traumatic brain injury (mTBI) remains a diagnostic challenge and therefore strategies for objective assessment of neurological function are key to limiting long-term sequelae. Current assessment methods are not optimal in austere environments su
Externí odkaz:
https://doaj.org/article/f70a3c3ffab84c8a93ba7f5dad646bd1
Autor:
Eric C. Gier, Alexis N. Pulliam, David A. Gaul, Samuel G. Moore, Michelle C. LaPlaca, Facundo M. Fernández
Publikováno v:
Metabolites, Vol 12, Iss 2, p 150 (2022)
Traumatic brain injury (TBI) poses a major health challenge, with tens of millions of new cases reported globally every year. Brain damage resulting from TBI can vary significantly due to factors including injury severity, injury mechanism and exposu
Externí odkaz:
https://doaj.org/article/4d8986bced564071b0ff7d9f385caf77
Autor:
James D. Ross, D. Kacy eCullen, James Patrick Harris, Michelle C. LaPlaca, Stephen P. DeWeerth
Publikováno v:
Frontiers in Neuroanatomy, Vol 9 (2015)
Three-dimensional (3-D) image analysis techniques provide a powerful means to rapidly and accurately assess complex morphological and functional interactions between neural cells. Current software-based identification methods of neural cells generall
Externí odkaz:
https://doaj.org/article/9aab4c722f4d4b39a18f7f3c9d829339
Autor:
Andrew J. Butler, Justiss Kallos, Stephen N. Housley, Michelle C. LaPlaca, Stephen F. Traynelis, Steven L. Wolf
Publikováno v:
Rehabilitation Research and Practice, Vol 2015 (2015)
Stroke is a leading cause of death and disability in the USA. Up to 60% of patients do not fully recover despite intensive physical therapy treatment. N-Methyl-D-aspartate receptors (NMDA-R) have been shown to play a role in synaptic plasticity when
Externí odkaz:
https://doaj.org/article/08e3ddf9f95e47b19ff5438885872197
Autor:
Matthew C. Tate, Deborah A. Shear, Stuart W. Hoffman, Donald G. Stein, David R. Archer, Michelle C. Laplaca Ph.D.
Publikováno v:
Cell Transplantation, Vol 11 (2002)
Multipotential stem cells are an attractive choice for cell therapy after traumatic brain injury (TBI), as replacement of multiple cell types may be required for functional recovery. In the present study, neural stem cells (NSCs) derived from the ger
Externí odkaz:
https://doaj.org/article/dca04317f4024041b43b0bace92124b8
Autor:
Gustavo R Prado, Michelle C LaPlaca
Publikováno v:
Neuroscience Insights, Vol 15 (2020)
The acute response of neurons subjected to traumatic loading involves plasma membrane disruption, yet the mechanical tolerance for membrane compromise, time course, and mechanisms for resealing are not well understood. We have used an in vitro trauma
Externí odkaz:
https://doaj.org/article/51a92f77688e4cbb8183c09741f043f7
Publikováno v:
Current Opinion in Biomedical Engineering. 27:100468
Autor:
Jonathan Lifshitz, David J. Loane, Nsini A. Umoh, Candace L. Floyd, Bridget E. Hawkins, J. Russell Huie, Audrey D. Lafrenaye, Adam D. Bachstetter, Adam R. Ferguson, Victoria E. Johnson, Hűlya Bayir, Chantelle Ferland-Beckham, Aristea S. Galanopoulou, Stuart H. Friess, L.E. Hulbert, Patricia Kabitzke, Ramona Hicks, Edward D. Hall, C. Edward Dixon, Aaron M. Williams, Linda J. Noble-Haeusslein, Diana M. Cummings, Douglas H. Smith, Patrick F. Bellgowan, Margaret Young, Vance Lemmon, Michelle C. LaPlaca, Laila J. Zai, Neil G. Harris, Olga Vovk, Carrie W. Lifshitz, Hasan B. Alam, Leonie Misquitta, Carol Taylor-Burds, Vahagn C. Nikolian
Publikováno v:
J Neurotrauma
Journal of neurotrauma, vol 38, iss 10
Journal of neurotrauma, vol 38, iss 10
Traumatic brain injury (TBI) is an extremely complex condition due to heterogeneity in injury mechanism, underlying conditions, and secondary injury. Pre-clinical and clinical researchers face challenges with reproducibility that negatively impact tr