Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michelle C. Flynn"'
Autor:
Charles D. Cohen, Miles J. De Blasio, Man K. S. Lee, Gabriella E. Farrugia, Darnel Prakoso, Crisdion Krstevski, Minh Deo, Daniel G. Donner, Helen Kiriazis, Michelle C. Flynn, Taylah L. Gaynor, Andrew J. Murphy, Grant R. Drummond, Alexander R. Pinto, Rebecca H. Ritchie
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Diabetes is associated with a significantly elevated risk of cardiovascular disease and its specific pathophysiology remains unclear. Recent studies have changed our understanding of cardiac cellularity, with cellular changes acco
Externí odkaz:
https://doaj.org/article/88aaad0eb056450fa3ffbe56d0335c20
Autor:
Nordin M. J. Hanssen, Michael J. Kraakman, Michelle C. Flynn, Prabhakara R. Nagareddy, Casper G. Schalkwijk, Andrew J. Murphy
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Clinical trials investigating whether glucose lowering treatment reduces the risk of CVD in diabetes have thus far yielded mixed results. However, this doesn't rule out the possibility of hyperglycemia playing a major causal role in promoting CVD or
Externí odkaz:
https://doaj.org/article/fe46a04627e34faf993da5147bd48de5
Autor:
Man K. S. Lee, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, Andrew J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Externí odkaz:
https://doaj.org/article/877fdbb79e87480fa17aaf1845695887
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease, in which macrophages are responsible for taking up these lipids and driving disease progression. Over the years, we and others have uncovered key pathways th
Externí odkaz:
https://doaj.org/article/1ce13b9d7dd74074ad93b1e39fb34141
Autor:
Michael J. Kraakman, Helene L. Kammoun, Dragana Dragoljevic, Annas Al-Sharea, Man K.S. Lee, Michelle C. Flynn, Christian J. Stolz, Andrew A. Guirguis, Graeme I. Lancaster, Jaye Chin-Dusting, David J. Curtis, Andrew J. Murphy
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obes
Externí odkaz:
https://doaj.org/article/737696cb60b3401b9c2f8491dfff23ce
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract The importance of metabolic regulation in the immune system has launched back into the limelight in recent years. Various metabolic pathways have been examined in the context of their contribution to maintaining immune cell homeostasis and f
Externí odkaz:
https://doaj.org/article/cf5a4729a1a44c3c873361e473fecd1a
Autor:
Andrew J. Murphy, Gabriella E. Farrugia, Man K.S. Lee, Miles J. De Blasio, Minh Deo, Charles D. Cohen, Alexander R. Pinto, Helen Kiriazis, Darnel Prakoso, Rebecca Helen Ritchie, Michelle C Flynn, Crisdion Krstevski, D. Donner, Grant R Drummond, Taylah L. Gaynor
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-12 (2021)
Cardiovascular Diabetology
Cardiovascular Diabetology
Background Diabetes is associated with a significantly elevated risk of cardiovascular disease and its specific pathophysiology remains unclear. Recent studies have changed our understanding of cardiac cellularity, with cellular changes accompanying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6938fac68c02d8b385165a695f25e8
https://doaj.org/article/88aaad0eb056450fa3ffbe56d0335c20
https://doaj.org/article/88aaad0eb056450fa3ffbe56d0335c20
Autor:
Man K.S. Lee, Emma C. Josefsson, Elizabeth Morriss, Nordin M J Hanssen, Michelle C Flynn, Camilla Bertuzzo-Veiga, Dragana Dragoljevic, Olivia D. Cooney, Andrew J. Murphy, Fatima Baig, Gopalkrishna Sreejit, Benjamin T. Kile, Annas Al-Sharea, Michael J Kraakman, Prabhakara R Nagareddy, Mark E. Cooper
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 41(3), 1167-1178. LIPPINCOTT WILLIAMS & WILKINS
Arterioscler Thromb Vasc Biol
Arteriosclerosis, thrombosis, and vascular biology, 41(3), 1167-1178. Lippincott Williams and Wilkins
Arterioscler Thromb Vasc Biol
Arteriosclerosis, thrombosis, and vascular biology, 41(3), 1167-1178. Lippincott Williams and Wilkins
Objective: People with diabetes are at a significantly higher risk of cardiovascular disease, in part, due to accelerated atherosclerosis. Diabetic subjects have increased number of platelets that are activated, more reactive, and respond suboptimall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2e32cd1cb4651ebc9a8e1a24ce8c90
https://doi.org/10.1161/atvbaha.120.315369
https://doi.org/10.1161/atvbaha.120.315369
Autor:
Raelene Pickering, Man K.S. Lee, Kyle L. Hoehn, Graeme I. Lancaster, Josephine M. Forbes, Michelle C Flynn, Ira J. Goldberg, Fiona Hortle, Ellen M. Olzomer, Tessa J. Barrett, Dragana Dragoljevic, Assam El-Osta, Domenica A. McCarthy, Merlin C. Thomas, Andrew J. Murphy, Frances L. Byrne, Edward A. Fisher, Liza Makowski, Nordin M J Hanssen, Annas Al-Sharea, Casper G. Schalkwijk, Helene L. Kammoun, Michael J Kraakman, Prabhakara R Nagareddy, Christos Tikellis, Mark E. Cooper
Publikováno v:
Circulation Research, 127(7), 877-892. LIPPINCOTT WILLIAMS & WILKINS
Circ Res
Circulation research, 127(7), 877-892. Lippincott Williams and Wilkins
Circ Res
Circulation research, 127(7), 877-892. Lippincott Williams and Wilkins
Rationale: Treatment efficacy for diabetes mellitus is largely determined by assessment of HbA1c (glycated hemoglobin A1c) levels, which poorly reflects direct glucose variation. People with prediabetes and diabetes mellitus spend >50% of their time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383655909ede56d0b90144cbbea30be5
https://doi.org/10.1161/circresaha.120.316653
https://doi.org/10.1161/circresaha.120.316653
Autor:
Andrew Cotterill, Andrew J. Murphy, Domenica A. McCarthy, Kurt T. K. Giuliani, Kim C. Donaghue, Janelle Nisbet, Preeti Chandrashekar, Kristen J. Radford, Anthony W. Russell, Michelle C Flynn, Timothy W. Jones, Andrew J. Kassianos, Nicole M. Isbel, Neisha D'Silva, Helen L. Barrett, Adam Morton, Jennifer J Couper, Helen Healy, Amelia K. Fotheringham, David W. Johnson, Mitchell A. Sullivan, Nicole B. Flemming, Tracey Baskerville, Mark Harris, Stephanie Teasdale, Anca Grivei, Sam Beard, Rani O. Whiddett, Trisha O'Moore-Sullivan, Josephine M. Forbes
Publikováno v:
Diabetes
Half of the mortality in diabetes is seen in individuals DKD risk was assigned in youth with type 1 diabetes [n=100; 20.0±2.8 yrs; M:F-54:46, HbA1C-66.1(12.3) mmol/mol; diabetes duration-10.7±5.2 yrs; BMI-24.5(5.3) kg.m-2] and 10 year historical uA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fdd231e18209162725dd431915bc99
https://doi.org/10.2337/figshare.14186459.v1
https://doi.org/10.2337/figshare.14186459.v1
