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pro vyhledávání: '"Michelle C. Culbertson"'
Autor:
Megan C. Duggan, Amanda R. Campbell, Elizabeth L. McMichael, Kallan S. Opheim, Kala M. Levine, Neela Bhave, Michelle C. Culbertson, Tiffany Noel, Lianbo Yu, WE Carson
Publikováno v:
OncoImmunology, Vol 7, Iss 2 (2018)
Natural killer (NK) cells serve a critical role in the immune response against microbes and developing tumors. We have demonstrated that NK cells produce stimulatory cytokines (e.g., IFN-γ) in response to potent stimulation via immobilized IgG (to e
Externí odkaz:
https://doaj.org/article/4c47c9ad878b428ca413947d3a358acb
Autor:
Jen-Yu Liao, Michelle C. Culbertson, Sujay P. Sau, Saikat Bala, Kartik Temburnikar, John C. Chaput
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(10)
Chemically modified oligonucleotides are routinely used as diagnostic and therapeutic agents due to their enhanced biological stability relative to natural DNA and RNA. Here, we examine the biological stability of α-l-threofuranosyl nucleic acid (TN