Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle C W Tang"'
Autor:
Michelle C W Tang, Shelley A Jacobs, Deidre M Mattiske, Yu May Soh, Alison N Graham, An Tran, Shu Ly Lim, Damien F Hudson, Paul Kalitsis, Moira K O'Bryan, Lee H Wong, Jeffrey R Mann
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004964 (2015)
Histones package DNA and regulate epigenetic states. For the latter, probably the most important histone is H3. Mammals have three near-identical H3 isoforms: canonical H3.1 and H3.2, and the replication-independent variant H3.3. This variant can acc
Externí odkaz:
https://doaj.org/article/fbdbd16026c44294a31791d6aec3ee14
Most paediatric diffuse intrinsic pontine gliomas carry a lysine- to methionine-27 (K27M) mutation in the histone variant H3.3 encoded by the ‘H3.3 histone A’ (H3F3A) gene. To establish a pre-clinical model of the disease we made a Cre/loxPcondit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe8c9b4e75636d0a9c13964d092c243
https://doi.org/10.1101/2022.11.25.518018
https://doi.org/10.1101/2022.11.25.518018
Publikováno v:
Chromosoma. 123:587-595
Histone variants can incorporate into the nucleosome outside of S-phase. Some are known to play important roles in mammalian germ cell development, this cell lineage being characterized by long phases of quiescence, a protracted meiotic phase, and ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aae8b75a6c4471c300a1ba74a09261a
https://doi.org/10.1007/s00412-014-0475-8
https://doi.org/10.1007/s00412-014-0475-8
Autor:
James D. R. McGhie, Jeffrey R. Mann, Melissa A. Anderson, K. H. Andy Choo, Fiona T. M. Chang, F. Lyn Chan, Michelle C. W. Tang, Lee H. Wong
Publikováno v:
Nucleic Acids Research
We have previously shown that α-thalassemia mental retardation X-linked (ATRX) and histone H3.3 are key regulators of telomeric chromatin in mouse embryonic stem cells. The function of ATRX and H3.3 in the maintenance of telomere chromatin integrity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5428fee5ebdca7f4133bc0f2fe818e7c
https://doi.org/10.1093/nar/gkt114
https://doi.org/10.1093/nar/gkt114
Publikováno v:
genesis. 51:142-146
Post-translational modifications to residues in core histones convey epigenetic information. Their function can be evaluated in amino acid substitution mutants, although to date this method has not been used in mice. To this end, we have evaluated ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e7b4e2e106daa7563fbaf6c7156394
https://doi.org/10.1002/dvg.22366
https://doi.org/10.1002/dvg.22366
Autor:
T M Fiona Chang, F. Lyn Chan, Michelle C. W. Tang, Lee Hwa Hwa Wong, James D. R. McGhie, Jeffrey R. Mann, Hilda A. Pickett, Maheshi Udugama, Lynne Mayne, Phillipe Collas
Publikováno v:
Nucleic Acids Research
In addition to being a hallmark at active genes, histone variant H3.3 is deposited by ATRX at repressive chromatin regions, including the telomeres. It is unclear how H3.3 promotes heterochromatin assembly. We show that H3.3 is targeted for K9 trimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd800ca77c2f65094c2a4337b486514
https://pubmed.ncbi.nlm.nih.gov/26304540
https://pubmed.ncbi.nlm.nih.gov/26304540
Autor:
Damien F. Hudson, Yu May Soh, Michelle C. W. Tang, Shu Ly Lim, Moira K O'Bryan, Jeffrey R. Mann, Alison N. Graham, Lee H. Wong, Paul Kalitsis, An Tran, Deidre M. Mattiske, Shelley A. Jacobs
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 11, Iss 2, p e1004964 (2015)
PLoS Genetics, Vol 11, Iss 2, p e1004964 (2015)
Histones package DNA and regulate epigenetic states. For the latter, probably the most important histone is H3. Mammals have three near-identical H3 isoforms: canonical H3.1 and H3.2, and the replication-independent variant H3.3. This variant can acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae450363fed557771f60005a2164849b
http://europepmc.org/articles/PMC4335506
http://europepmc.org/articles/PMC4335506