Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Michelle C Janelsins"'
Autor:
Aaron N. Huynh, AnnaLynn M. Williams, Elizabeth K. Belcher, Paige Van Haute, Louis T. Lotta, Bryan Thompson, Colleen Netherby-Winslow, Amarinthia Curtis, Benjamin T. Esparaz, Carla Jorgensen, Sara Alberti, Emma Bentley, Hongying Sun, Eva Culakova, Michelle C. Janelsins
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100860- (2024)
Many patients with cancer experience cancer-related cognitive decline (CRCD). Previous studies have shown that elevated S100β, a calcium-binding protein commonly found in glial cells, can exhibit neurotoxic effects, including disruption of the blood
Externí odkaz:
https://doaj.org/article/a77917e415c14ed6813c9f050e073d76
Autor:
Kah Poh Loh, Ying Wang, Chandrika Sanapala, Nikesha Gilmore, Colleen Netherby-Winslow, Jason H. Mendler, Jane Liesveld, Eric Huselton, AnnaLynn M. Williams, Heidi D. Klepin, Marielle Jensen-Battaglia, Karen Mustian, Paula Vertino, Martha Susiarjo, Michelle C. Janelsins
Publikováno v:
Experimental Gerontology, Vol 187, Iss , Pp 112364- (2024)
Tumor necrosis factor (TNF)α is a major regulator of inflammation. However, the epigenetic regulation of TNFα in the context of an exercise intervention among older adults with cancer is understudied. In this exploratory analysis, we used data from
Externí odkaz:
https://doaj.org/article/a2c5f7669d0d4a2a84a1f0ed403061bd
Autor:
Kah Poh Loh, Chandrika Sanapala, Marielle Jensen-Battaglia, Anish Rana, Michael B. Sohn, Erin Watson, Nikesha Gilmore, Heidi D. Klepin, Jason H. Mendler, Jane Liesveld, Eric Huselton, Marissa LoCastro, Martha Susiarjo, Colleen Netherby-Winslow, AnnaLynn M. Williams, Karen Mustian, Paula Vertino, Michelle C. Janelsins
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-12 (2023)
Abstract Background Older adults with myeloid malignancies are susceptible to treatment-related toxicities. Accelerated DNAm age, or the difference between DNA methylation (DNAm) age and chronological age, may be used as a biomarker of biological age
Externí odkaz:
https://doaj.org/article/94c15e53c0a8487788c69f26cd8fc038
Autor:
Sara J. Hardy, Sanjukta Bandyopadhyay, Hongmei Yang, Annalynn Williams, Abdi Gudina, Michael A. Cummings, Hong Zhang, Deepinder P. Singh, Yuhchyau Chen, Nimish A. Mohile, Michelle C. Janelsins, Michael T. Milano
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectivesHead and neck cancer is a common malignancy frequently treated with chemotherapy and radiotherapy. Studies have shown an increased risk of stroke with the receipt of radiotherapy, but data on stroke-related mortality are limited, particular
Externí odkaz:
https://doaj.org/article/548484f1f10c4b53b9072614ef7ec642
Autor:
Song Yao, Qiang Hu, Sarah Kerns, Li Yan, Adedayo A. Onitilo, Jamal Misleh, Kelley Young, Lianlian Lei, Javier Bautista, Mostafa Mohamed, Supriya G. Mohile, Christine B. Ambrosone, Song Liu, Michelle C. Janelsins
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-10 (2019)
Abstract Background Little is known about the effects of chemotherapeutic drugs on DNA methylation status of leukocytes, which may be predictive of treatment benefits and toxicities. Based on a prospective national study, we characterize the changes
Externí odkaz:
https://doaj.org/article/688c0ba8a21f4a47893ef35afcf29e1d
Autor:
Maryam Omran, Elizabeth K. Belcher, Nimish A. Mohile, Shelli R. Kesler, Michelle C. Janelsins, Andrea G. Hohmann, Ian R. Kleckner
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating, and dose-limiting side effect of many chemotherapy regimens yet has limited treatments due to incomplete knowledge of its pathophysiology. Research on the pathophysiology of
Externí odkaz:
https://doaj.org/article/c6727e0e42584ad6a16350f409dfb878
Autor:
Elizabeth K. Belcher, Tara B. Sweet, Berke Karaahmet, Dawling A. Dionisio-Santos, Laura D. Owlett, Kimberly A. Leffler, Michelle C. Janelsins, Jacqueline P. Williams, John A. Olschowka, M. Kerry O’Banion
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 4, Iss , Pp 100057- (2020)
Microglia, the resident immune cells of the central nervous system (CNS), play multiple roles in maintaining CNS homeostasis and mediating tissue repair, including proliferating in response to brain injury and disease. Cranial irradiation (CI), used
Externí odkaz:
https://doaj.org/article/b1b3941c6d4048c08c34b0112955121c
Autor:
Amber S. Kleckner, Ian R. Kleckner, Charles S. Kamen, Mohamedtaki A. Tejani, Michelle C. Janelsins, Gary R. Morrow, Luke J. Peppone
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Cannabis has the potential to modulate some of the most common and debilitating symptoms of cancer and its treatments, including nausea and vomiting, loss of appetite, and pain. However, the dearth of scientific evidence for the effectiveness of cann
Externí odkaz:
https://doaj.org/article/5ee09d58cfa54d4ca0ab5bc97c5fd4cb
Autor:
Po-Ju Lin PhD, MPH, Ian R. Kleckner PhD, MPH, Kah Poh Loh MD, Julia E. Inglis PhD, Luke J. Peppone PhD, MPH, Michelle C. Janelsins PhD, MPH, Charles S. Kamen PhD, MPH, Charles E. Heckler PhD, MS, Eva Culakova PhD, Wilfred R. Pigeon PhD, Pavan S. Reddy MD, Michael J. Messino MD, Rakesh Gaur MD, MPH, Karen M. Mustian PhD, MPH
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
Background: Cancer-related fatigue (CRF) often co-occurs with sleep disturbance and is one of the most pervasive toxicities resulting from cancer and its treatment. We and other investigators have previously reported that yoga therapy can improve sle
Externí odkaz:
https://doaj.org/article/acd47490f30042b3a5328ff25f01b17d
Autor:
Jim, Aasha I. Hoogland, Brent J. Small, Laura B. Oswald, Crystal Bryant, Yvelise Rodriguez, Brian D. Gonzalez, Xiaoyin Li, Michelle C. Janelsins, Hailey W. Bulls, Brian W. James, Bianca Arboleda, Claudia Colon-Echevarria, Mary K. Townsend, Shelley S. Tworoger, Paulo C. Rodriguez, Julienne E. Bower, Sachin M. Apte, Robert M. Wenham, Heather S. L.
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3407
Previous research suggests that inflammation triggers cancer-treatment-related symptoms (i.e., fatigue, depression, and disruptions in sleep and physical activity), but evidence is mixed. This study examined relationships between inflammatory biomark