Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Michelle Becker"'
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110687- (2024)
Summary: Chemical synaptic transmission is modulated to accommodate different activity levels, thus enabling homeostatic scaling in pre- and postsynaptic compartments. In nematodes, cholinergic neurons use neuropeptide signaling to modulate synaptic
Externí odkaz:
https://doaj.org/article/8a9822cab6a544b396e05fc3fadc6fc8
Autor:
Nancy D. Marin, Michelle Becker-Hapak, Wilbur M. Song, Quazim A. Alayo, Lynne Marsala, Naomi Sonnek, Melissa M. Berrien-Elliott, Mark Foster, Jennifer A. Foltz, Jennifer Tran, Pamela Wong, Celia C. Cubitt, Patrick Pence, Kimberly Hwang, Alice Y. Zhou, Miriam T. Jacobs, Timothy Schappe, David A. Russler-Germain, Ryan C. Fields, Matthew A. Ciorba, Todd A. Fehniger
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTMetastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient (dMMR)/microsatellit
Externí odkaz:
https://doaj.org/article/989a296ad9bc48bf902f4f5ef1d3f555
Autor:
Marcela Torikachvili, Mariana Soares Silva, Michelle Becker Petersen, Fabiana Quoos Mayer, Renata da Fontoura Budaszewski, Matheus Nunes Weber, João Antonio Tadeu Pigatto, Cláudio Wageck Canal, Franciele Maboni Siqueira
Publikováno v:
Ciência Animal Brasileira, Vol 25 (2024)
The conjunctiva plays an essential role in eye health and immunity and acts as a barrier to the entry of microorganisms. Conjunctival infections are common in dogs and result from both the invasion of pathogenic microorganisms and the uncontrolled gr
Externí odkaz:
https://doaj.org/article/470139fc3dc04819b9d7f284d4101d66
Autor:
Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Since the T-box transcription factors (TFs) T-BET and EOMES are necessary for initiation of NK cell development, their ongoing requirement for mature NK cell homeostasis, function, and molecular programming remains unclear. To address this, T-BET and
Externí odkaz:
https://doaj.org/article/74062db604294ed99bc9e3922c1fadcb
Autor:
Celia C. Cubitt, Ethan McClain, Michelle Becker-Hapak, Jennifer A. Foltz, Pamela Wong, Julia A. Wagner, Carly C. Neal, Nancy D. Marin, Lynne Marsala, Mark Foster, Timothy Schappe, Patrick Soon-Shiong, John Lee, Melissa M. Berrien-Elliott, Todd A. Fehniger
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 585-596 (2022)
Natural killer (NK) cells are cytotoxic innate lymphoid cells that are emerging as a cellular immunotherapy for various malignancies. NK cells are particularly dependent on interleukin (IL)-15 for their survival, proliferation, and cytotoxic function
Externí odkaz:
https://doaj.org/article/eae306c4582b4e83bf8e75562e6acbf7
Autor:
Marcele de Souza Muccillo, Alessandra Fernandez da Silva, Maiara Poersch Seibel, Renata Lima Baptista, Marcela Torikachvili, Michelle Becker Petersen, João Antonio Tadeu Pigatto
Publikováno v:
Ciência Rural, Vol 51, Iss 10 (2021)
ABSTRACT: The objective of this study was to evaluate the acute effects of ropivacaine hydrochloride on the corneal endothelium of horses. Forty-eight eyes were obtained from a commercial slaughterhouse and were randomly divided into three groups. In
Externí odkaz:
https://doaj.org/article/1913e70ffe204445bae1215c81e72e49
Publikováno v:
Animals, Vol 12, Iss 13, p 1728 (2022)
Background: Owners often feel the cost of veterinary care is too high, as there remains a limited understanding of the cost of health care in human and veterinary medicine alike. Pet health insurance is often seen as a universal solution. However, es
Externí odkaz:
https://doaj.org/article/7a4829edb6b64fb6af931e94d13a943e
Autor:
Li Li, Martin Treder, Mark Foster, Lucila Kerbauy, Nancy Marin, Mecit Kaplan, Pinaki Banerjee, Melissa Berrien-Elliott, Michelle Becker-Hapak, Rafet Basar, Luciana Garcia Melo, Carly Neal, Ethan McClain, May Daher, Ana Karen Nunez Cortes, Sweta Desai, Francesca Wei Inng Lim, Mayela Carolina Mendt, Timothy Schappe, Hila Shaim, Mayra Hernandez Sanabria, Pamela Wong, Enli Liu, Sonny Ang, Rong Cai, Vandana Nandivada, Vakul Mohanty, Yifei Shen, Natalia Baran, Natalie Fowlkes, Ken Chen, Luis Muniz-Feliciano, Joachim Koch, Wolfgang Fischer, Oswaldo Keith Okamoto, Yago Nieto, Richard Champlin, Elizabeth Shpall, Todd Fehniger, Katy Rezvani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/5b9f3404348e403bad3e294fdcc2c3ea
Autor:
Sheena Crosby, Michael J Schuh, Michelle Becker, Marina Ivanov, Freddy Caldera, Francis A Farraye
Publikováno v:
Inflammatory Bowel Diseases. 29:661-664
Patients with inflammatory bowel disease (IBD) are at a high risk of developing invasive pneumococcal infection both before and after they are diagnosed. The Advisory Committee on Immunization Practices now endorses use of 2 new pneumococcal conjugat
Autor:
Abhinav Vasudevan, Vivek Tharayil, Laura H Raffals, David H Bruining, Michelle Becker, Mohammad Hassan Murad, Edward V Loftus
Publikováno v:
Inflammatory Bowel Diseases.
Background Optimizing therapy and monitoring response are integral aspects of inflammatory bowel disease treatment. We conducted a systematic review and meta-analysis to determine whether serum ustekinumab trough concentrations during maintenance the