Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michelle B. Nadler"'
Autor:
Coralea Kappel, Mitchell J. Elliott, Vikaash Kumar, Michelle B. Nadler, Alexandra Desnoyers, Eitan Amir
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Individual trials of abemaciclib, palbociclib, and ribociclib show a similar impact on progression-free survival yet differing statistical significance for overall survival (OS). A robust comparative evaluation of OS, safety, and tolerabilit
Externí odkaz:
https://doaj.org/article/997bc7afc1c34d8484e22a43f20d8e39
Autor:
Michelle B. Nadler, Brooke E. Wilson, Alexandra Desnoyers, Consolacion Molto Valiente, Ramy R. Saleh, Eitan Amir
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Approval of drugs is based on randomized trials observing statistically significant superiority of an experimental agent over a standard. Statistical significance results from a combination of effect size and sampling, with larger effect siz
Externí odkaz:
https://doaj.org/article/ad2621f4f2e041a0828784637ed92982
Autor:
Michelle B. Nadler, Ann Marie Corrado, Brooke E. Wilson, Alexandra Desnoyers, Eitan Amir, Noah Ivers, Laura Desveaux
Publikováno v:
BMC Women's Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Canadian and US Task Forces recommend against routine mammography screening for women age 40–49 at average breast cancer risk as harms outweigh benefits. Both suggest individualized decisions based on the relative value women pl
Externí odkaz:
https://doaj.org/article/974b1ba604e4489eb02ed66b2503465c
Autor:
Michelle B. Nadler, Brooke E. Hofbauer, Melinda Wu, Susan Hum, Christine Elser, Joyce Nyhof-Young
Publikováno v:
Current Oncology, Vol 29, Iss 9, Pp 6485-6495 (2022)
Background: Family physicians have low knowledge and preparedness to manage patients with cancer. A breast oncology clinical rotation was developed for family medicine residents to address this gap in medical education. Objectives and Methods: A brea
Externí odkaz:
https://doaj.org/article/29aa1c413ef74c1685aee949f5e637e4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Disease-free survival (DFS) comprises both breast cancer and non-breast cancer events. DFS has not been validated as a surrogate endpoint for overall survival (OS) in most breast cancer subtypes. We assessed changes to the type of events con
Externí odkaz:
https://doaj.org/article/53f8d1a009264e47a7bfc96b3408925c
Publikováno v:
Journal of the National Comprehensive Cancer Network. 19:1433-1440
Background: Censoring due to early drug discontinuation (EDD) or withdrawal of consent or loss to follow-up (WCLFU) can result in postrandomization bias. In oncology, censoring rules vary with no defined standards. In this study, we sought to describ
Autor:
Michelle B. Nadler, Ann Marie Corrado, Laura Desveaux, Sarah E. Neil-Sztramko, Brooke E. Wilson, Alexandra Desnoyers, Eitan Amir, Noah Ivers
Publikováno v:
CMAJ open. 10(4)
Although the current Canadian Task Force on Preventive Health Care guideline recommends that physicians should inform women aged 40-49 years of the potential benefits and harms of screening mammography to support individualized decisions, previous re
Autor:
Brooke E Wilson, Aisha Lofters, Alexandra Desnoyers, Eitan Amir, Alex Marchand-Austin, Noah Ivers, Michelle B. Nadler, Peter C. Austin
Publikováno v:
Breast Cancer Research and Treatment. 189:631-640
Canadian breast cancer screening guidelines state that mammography screening for women 40–49 should be individualized based on risk assessment and preferences. This retrospective cohort study describes the frequency of screening in women aged 40–
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5405-5414 (2021)
Cancer Medicine
Cancer Medicine
Background It has been suggested that the results from fragile trials are less likely to translate into benefit in routine clinical practice. Methods We searched the Food and Drug Administration (FDA) archives to identify drug approvals for solid org
Autor:
Rodrigo A Carrasco, Husam Abdel-Qadir, Sanjog Kalra, Paaladinesh Thavendiranathan, David Bobrowski, Montserrat Carrillo-Estrada, Michelle B. Nadler
Publikováno v:
Current Opinion in Cardiology. 36:597-608
Purpose of review Coronary artery disease (CAD) is a common comorbidity in patients with cancer. We review shared risk factors between the two diseases and cancer treatments that increase the risk of CAD. We also discuss outcomes and management consi