Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michelle B. Miranda"'
Autor:
Rongxiu Li, Amanda L. Boehm, Michelle B. Miranda, Sanjeev Shangary, Jennifer R. Grandis, Daniel E Johnson
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 10, Pp 801-811 (2007)
Head, neck squamous cell carcinomas (HNSCCs) are frequently characterized by chemotherapy, radiation resistance, by overexpression of Bcl-XL, an antiapoptotic member of the Bcl-2 protein family. In this report, we examined whether cell-permeable pept
Externí odkaz:
https://doaj.org/article/6399e6065d584a95809896390bb0ce7b
Autor:
Cecilia L. Llave, Maria Esterlita V. Uy, Hilton Y. Lam, Josephine G. Aldaba, Clarence C. Yacapin, Michelle B. Miranda, Haidee A. Valverde, Wilda T. Silva, Saira Nawaz, Rose C. Slavkovsky, Jessica Mooney, Elisabeth L. Vodicka
Publikováno v:
Vaccine. 40(27)
Cervical cancer is the second most common cancer among women in the Philippines. Human papillomavirus (HPV) vaccination provides protection from the most common cancer-causing HPV types. This analysis used a proportionate outcomes model to estimate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a1b9b271046832cb6b5db080096e3f
https://pubmed.ncbi.nlm.nih.gov/35606237
https://pubmed.ncbi.nlm.nih.gov/35606237
Autor:
Jennifer R. Grandis, R Duan, Sufi M. Thomas, Daniel Johnson, Robert L. Redner, Michelle B. Miranda, J E Jones
Publikováno v:
Leukemia. 22:1624-1627
Acute myeloid leukemias (AMLs) are characterized by a variety of genetic defects that contribute to the failure of these cells to undergo differentiation to mature granulocytes or monocytes/macrophages. A primary consequence of this failure to differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3ef52c28fcd6c2386022a3138ded17
https://doi.org/10.1038/leu.2008.28
https://doi.org/10.1038/leu.2008.28
Publikováno v:
Molecular Cancer Therapeutics. 6:3081-3090
Treatment of acute promyelocytic leukemia with retinoic acid (RA) results in differentiation of the leukemic cells and clinical remission. However, the cellular factors that regulate RA-induced myeloid differentiation are largely unknown, and other f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd1aeaf28e737314eeef0fff0aeca1b
https://doi.org/10.1158/1535-7163.mct-07-0514
https://doi.org/10.1158/1535-7163.mct-07-0514
Autor:
Lori A. Emert-Sedlak, Sanjeev Shangary, Daniel Johnson, Michelle B. Miranda, Asaf Rabinovitz, Scott M. Delach
Publikováno v:
Molecular Cancer Therapeutics. 4:733-742
Treatment of cells with chemotherapy drugs activates the intrinsic mitochondrial pathway of apoptosis and the caspase protease cascade. Recently, the lysosomal protease cathepsin D has been implicated in apoptosis caused by oxidative stress, inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6de75432ad694a231fb1f246b69e28
https://doi.org/10.1158/1535-7163.mct-04-0301
https://doi.org/10.1158/1535-7163.mct-04-0301
Autor:
Christopher L. Oliver, Michelle B. Miranda, Sanjeev Shangary, Stephanie Land, Shaomeng Wang, Daniel E. Johnson
Publikováno v:
Molecular Cancer Therapeutics. 4:23-31
Aberrant overexpression of antiapoptotic members of the Bcl-2 protein family, including Bcl-2 and Bcl-XL, contributes to malignant transformation and subsequent resistance to traditional chemotherapeutics. Thus, these proteins represent attractive ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbff6349f3bf40f14a2931748c82fa0
https://doi.org/10.1158/1535-7163.23.4.1
https://doi.org/10.1158/1535-7163.23.4.1
Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines
Publikováno v:
Leukemia. 16:683-692
Activation of the MEK/ERK/MAP kinase signaling pathway promotes the proliferation and survival of hematopoietic cells. The kinases MEK-1, MEK-2, ERK-1/MAPK and ERK-2/MAPK are activated by phosphorylation at specific sites, and these events can be mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70eddc20c64f8d85b43a1cc144427a2
https://doi.org/10.1038/sj.leu.2402400
https://doi.org/10.1038/sj.leu.2402400
Autor:
Michelle B. Miranda, Daniel Johnson
Publikováno v:
Leukemia. 21(7)
The production of mature, differentiated myeloid cells is regulated by the action of hematopoietic cytokines on progenitor cells in the bone marrow. Cytokines drive the process of myeloid differentiation by binding to specific cell-surface receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9984ef9dd0af9646f398d487683ac535
https://pubmed.ncbi.nlm.nih.gov/17443228
https://pubmed.ncbi.nlm.nih.gov/17443228
Autor:
Christopher L, Oliver, Michelle B, Miranda, Sanjeev, Shangary, Stephanie, Land, Shaomeng, Wang, Daniel E, Johnson
Publikováno v:
Molecular cancer therapeutics. 4(1)
Aberrant overexpression of antiapoptotic members of the Bcl-2 protein family, including Bcl-2 and Bcl-X(L), contributes to malignant transformation and subsequent resistance to traditional chemotherapeutics. Thus, these proteins represent attractive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b874385e74e6eecbe97b9a82a0bfb1eb
https://pubmed.ncbi.nlm.nih.gov/15657350
https://pubmed.ncbi.nlm.nih.gov/15657350
Publikováno v:
Leukemia research. 29(11)
The intracellular signaling pathways that mediate cytokine-induced granulocytic and monocytic differentiation are incompletely understood. In this study, we examined the importance of the MEK/ERK signal transduction pathway in granulocyte-colony stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbded6937219ff10a89ee43df1b6e95
https://pubmed.ncbi.nlm.nih.gov/16098586
https://pubmed.ncbi.nlm.nih.gov/16098586