Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michelle Aszterbaum"'
Autor:
Ervin H. Epstein, David R. Bickers, Levy Kopelovich, Charles E. McCulloch, Michael A. Kohn, Xiuwei Tang, Po-Lin So, Ying Lu, Arianna Kim, Yefim Khaimskiy, Jimmy Hwang, Jennifer Hebert, Nini Estevez, Carol Cappola, Franco Barsanti, Mohammad Athar, Michelle Aszterbaum, Jean Y. Tang
Perspectives on this Article from Basal Cell Carcinoma Chemoprevention with Nonsteroidal Anti-inflammatory Drugs in Genetically Predisposed PTCH1+/− Humans and Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9421bb386601f08e973c39cb40e49e4d
https://doi.org/10.1158/1940-6207.22525689
https://doi.org/10.1158/1940-6207.22525689
Autor:
Ervin H. Epstein, David R. Bickers, Levy Kopelovich, Charles E. McCulloch, Michael A. Kohn, Xiuwei Tang, Po-Lin So, Ying Lu, Arianna Kim, Yefim Khaimskiy, Jimmy Hwang, Jennifer Hebert, Nini Estevez, Carol Cappola, Franco Barsanti, Mohammad Athar, Michelle Aszterbaum, Jean Y. Tang
In vitro and epidemiologic studies favor the efficacy of nonsteroidal anti-inflammatory drugs (NSAID) in preventing skin squamous photocarcinogenesis, but there has been relatively little study of their efficacy in preventing the more common skin bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6077cd339a6e4259602160c0ccd67b39
https://doi.org/10.1158/1940-6207.c.6544860
https://doi.org/10.1158/1940-6207.c.6544860
Autor:
Griffin Lentsch, Erica G. Baugh, Bonnie Lee, Michelle Aszterbaum, Christopher B. Zachary, Kristen M. Kelly, Mihaela Balu
Publikováno v:
The Journal of investigative dermatology. 142(5)
Over the past few years, high-resolution optical imaging technologies such as optical coherence tomography (OCT), reflectance confocal microscopy (RCM), and multiphoton microscopy (MPM) have advanced significantly as new methodologies for clinical re
Autor:
Jean Y. Tang, Ervin H. Epstein, Melika Rezaee, Michelle Aszterbaum, David R. Bickers, Anita M. Chanana, Mina S. Ally, Joselyn Lindgren, Charlotte Clark, Jackleen Marji, Ginny Gildengorin, Grace Ulerio, Julian Mackay-Wiggan
Publikováno v:
The Lancet. Oncology. 17(12)
Aberrant hedgehog signalling underlies the development of basal-cell carcinomas. We previously reported the interim analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial in patients with the basal-cell nevus (Gorlin)
Autor:
Ervin H. Epstein, Po-Lin So, Yefim Khaimskiy, Michelle Aszterbaum, Nancy Daniallinia, Jennifer Hebert, Alexander W. Langston, Michele A. Fujimoto
Publikováno v:
Experimental Dermatology. 15:742-750
There have been few reports of successful long-term culture of cells established from cutaneous basal cell carcinoma (BCC) tumors. Here, we describe techniques that have enabled us to establish three long-term cultures of BCC cells isolated from BCC
Autor:
Lela A. Lee, Michelle Aszterbaum, Patrick Walsh, Lih-Jen Su, Kristi Penheiter, Eva R. Parker, Angela Marchbank, Robert P. Dellavalle, Ervin H. Epstein, Timothy B.E. Grayson, James DeGregori
Publikováno v:
Experimental Dermatology. 11:203-208
Chronic ulcerative stomatitis protein (CUSP), the most abundant cutaneous isoform of p63, is a p53-related gene essential for epithelial development. CUSP lacks the N-terminal transactivation domain found on other p53 family members and has been show
Autor:
David R. Bickers, Joselyn Lindgren, Julian Mackay-Wiggan, Ervin H. Epstein, Michelle Aszterbaum, Maria Acosta Raphael, Bobbye J. Thompson, Anita M. Chanana, Albert S. Chiou, Jean Y. Tang, Wayne Lee
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 7(3)
Sporadic human basal cell carcinomas (BCCs) are generally well managed with current surgical modalities. However in the subset of high-risk patients predisposed to developing large numbers of BCCs, there is an unmet need for effective, low morbidity
Autor:
Christopher B. Zachary, Xiaoli Zhang, Jeannette M. Bonifas, Ervin H. Epstein, Michelle Aszterbaum, Frank McCormick, Jingwu Xie
Publikováno v:
Proceedings of the National Academy of Sciences. 98:9255-9259
Activation of the hedgehog pathway, through the loss of patched (PTC) or the activation of smoothened (SMO), occurs frequently in basal cell carcinoma (BCC), the most common human cancer. However, the molecular basis of this neoplastic effect is not
Autor:
Kathy P. An, Arianna L. Kim, Michelle Aszterbaum, David R. Bickers, Jack Longley, Ervin H. Epstein, Kimberly D. Morel, Mohammad Athar
Publikováno v:
Biochemical and Biophysical Research Communications. 280:1042-1047
Cyclooxygenase (COX) is the rate-limiting enzyme in the production of prostaglandins from arachidonic acid. This enzyme exists in at least two isoforms, COX-1 and COX-2. COX-1 is constitutively expressed in most tissues and plays various physiologica
Autor:
Farishta Khugyani, Mohammad Athar, Jennifer Hebert, Michelle Aszterbaum, Levy Kopelovich, Ervin H. Epstein
Publikováno v:
Skin Pharmacology and Physiology. 14:358-362
Skin cancers are a rising menace as their incidence increases, attributed in part to increasing ultraviolet radiation exposure. This increasing problem has stimulated efforts to devise useful preventive approaches. The uncertain efficacy of exhortati