Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Michelle A. Sahai"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Stimulant drugs, including novel psychoactive substances (NPS, formerly “legal highs”) have addictive potential which their users may not realize. Stimulants increase extracellular dopamine levels in the brain, including the reward and addiction
Externí odkaz:
https://doaj.org/article/c22f8b634c564bc9a5f45b09c0923a32
Autor:
Karen Handschuh, Jennifer Feenstra, Matthew Koss, Elisabetta Ferretti, Maurizio Risolino, Rediet Zewdu, Michelle A. Sahai, Jean-Denis Bénazet, Xiao P. Peng, Michael J. Depew, Laura Quintana, James Sharpe, Baolin Wang, Heather Alcorn, Roberta Rivi, Stephen Butcher, J. Robert Manak, Thomas Vaccari, Harel Weinstein, Kathryn V. Anderson, Elizabeth Lacy, Licia Selleri
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 674-687 (2014)
Sorting and degradation of receptors and associated signaling molecules maintain homeostasis of conserved signaling pathways during cell specification and tissue development. Yet, whether machineries that sort signaling proteins act preferentially on
Externí odkaz:
https://doaj.org/article/fac2dc6a120c4b5a81b814c1c6b66887
Publikováno v:
Brain Sciences, Vol 8, Iss 4, p 63 (2018)
Novel psychoactive substances (NPS) may have unsuspected addiction potential through possessing stimulant properties. Stimulants normally act at the dopamine transporter (DAT) and thus increase dopamine (DA) availability in the brain, including nucle
Externí odkaz:
https://doaj.org/article/27191e0b28b042129dbc93d9b9297fdf
Publikováno v:
Neuronal Signaling
Drug misuse is a significant social and public health problem worldwide. Misused substances exert their neurobehavioural effects through changing neural signalling within the brain, many of them leading to substance dependence and addiction in the lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaf09fb3eaa3f4f30647614a4d857f5
https://doi.org/10.1042/ns20210006
https://doi.org/10.1042/ns20210006
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Stimulant drugs, including novel psychoactive substances (NPS, formerly "legal highs") have addictive potential which their users may not realize. Stimulants increase extracellular dopamine levels in the brain, including the reward and addiction path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0e665d0e4fcccea7db2f6c9d62275c
http://europepmc.org/articles/PMC7289955
http://europepmc.org/articles/PMC7289955
Autor:
Denise Hernandez-Hopkins, Kenneth M. Kaye, Yifang Liu, J. David Warren, Jennifer Totonchy, Ethel Cesarman, Ruben Niesvizky, Ilaria Guasparri, Peter Barelli, David Jayabalan, Hufeng Zhou, Olivier Elemento, Duane C. Hassane, Michelle A. Sahai, Robert H. Shoemaker, Gunkut Akar, Utthara Nayar, Shizuko Sei, Jonathan Reichel, Jouliana Sadek
Publikováno v:
Journal of Clinical Investigation. 127:2066-2080
Primary effusion lymphoma (PEL) is a largely incurable malignancy of B cell origin with plasmacytic differentiation. Here, we report the identification of a highly effective inhibitor of PEL. This compound, 6-ethylthioinosine (6-ETI), is a nucleoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a8b8524ba3f0393b11c0ead03b0737
https://doi.org/10.1172/jci83936
https://doi.org/10.1172/jci83936
Publikováno v:
Methods
Molecular dynamics (MD) simulations have developed into an invaluable tool in bimolecular research, due to the capability of the method in capturing molecular events and structural transitions that describe the function as well as the physiochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c352bec6784c86fe8d4c120cb6a618
https://pubmed.ncbi.nlm.nih.gov/32081744
https://pubmed.ncbi.nlm.nih.gov/32081744
Autor:
Oliver Beckstein, Stephen A. Baldwin, Florian Brueckner, Arwen R. Pearson, Peter J. F. Henderson, Antonio N. Calabrese, Scott M. Jackson, Ekaterina Ivanova, Alison E. Ashcroft, Alexander D. Cameron, Edmund R.S. Kunji, Maria Kokkinidou, Tatsuro Shimamura, So Iwata, David Sharples, Simone Weyand, Irshad Ahmad, Michelle A. Sahai, Katie J. Simmons, Shunichi Suzuki, Homa Majd, Anna Polyakova
Publikováno v:
Encyclopedia of Biophysics ISBN: 9783642359439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b01547867432ad4404e80da8992c55a
https://doi.org/10.1007/978-3-642-35943-9_10091-2
https://doi.org/10.1007/978-3-642-35943-9_10091-2
Publikováno v:
Biophysical Journal. 120:123a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c14e1c7a0551e8ef6cc15c5b3f33170e
https://doi.org/10.1016/j.bpj.2020.11.957
https://doi.org/10.1016/j.bpj.2020.11.957
Publikováno v:
Brain Sciences; Volume 8; Issue 4; Pages: 63
Brain Sciences
Brain Sciences, Vol 8, Iss 4, p 63 (2018)
Brain Sciences
Brain Sciences, Vol 8, Iss 4, p 63 (2018)
Novel psychoactive substances (NPS) may have unsuspected addiction potential through possessing stimulant properties. Stimulants normally act at the dopamine transporter (DAT) and thus increase dopamine (DA) availability in the brain, including nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c0a9df8c290abdb3e2250bc4eb5602