Výsledky vyhledávání - "Michelle A. Mulcahey"

Effect of epinephrine deficiency on cold tolerance and on brown adipose tissue

Autor: Maria Joachim, Michelle A. Mulcahey, Rana Sharara-Chami, Joseph A. Majzoub, Steven N. Ebert

Publikováno v: Molecular and Cellular Endocrinology. 328:34-39

Catecholamines are involved in thermogenesis. We investigated the specific role of epinephrine in regulation of temperature homeostasis in mice. We subjected adult wildtype (WT) and phenylethanolamine N-methyl transferase knock out mice (Pnmt(-/-)) l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf26d7fdbd42bcf8ede499a2e1640912
https://doi.org/10.1016/j.mce.2010.06.019

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Type 2 Deiodinase Expression Is Induced by Peroxisomal Proliferator-Activated Receptor-γ Agonists in Skeletal Myocytes

Autor: Matthew L. Rosene, Brian W. Kim, Scott Ribich, Michelle A. Mulcahey, Antonio C. Bianco, Mary Elizabeth Patti, Renata Grozovsky, Stephen A. Huang

Publikováno v: Endocrinology. 150:1976-1983

The thyroid hormone activating type 2 deiodinase (D2) is known to play a role in brown adipose tissue-mediated adaptive thermogenesis in rodents, but the finding of D2 in skeletal muscle raises the possibility of a broader metabolic role. In the curr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f5df2e6168a7d1db3ab2d65806a4fb
https://doi.org/10.1210/en.2008-0938

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Consumptive hypothyroidism resulting from hepatic vascular tumors in an athyreotic adult

Autor: Joshua P. Klopper, Domenico Salvatore, Michael Wachs, Stephen A. Huang, Francisco G. La Rosa, Jennifer Sang-Lee, Michelle A. Mulcahey, David J. Howard

Publikováno v: The Journal of clinical endocrinology and metabolism. 96(7)

Consumptive hypothyroidism is a rare syndrome resulting from increased catabolism of T(4) and T(3) by increased type 3 iodothyronine deiodinase (D3) activity. Consumptive hypothyroidism has primarily been described as a paraneoplastic syndrome in inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f53b9e78a6c8d481818f3919205964f
https://pubmed.ncbi.nlm.nih.gov/21508133

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TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine

Autor: Xin Zhang, Erin A. Clark, Yujiang Geno Shi, Michelle A. Mulcahey, Stephen A. Huang, Haikuo Zhang

Publikováno v: Cell research. 20(12)

TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab4b7a8846466ff68842be4300be7ab
https://pubmed.ncbi.nlm.nih.gov/21079648

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Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism

Autor: P. Reed Larsen, Luciana A. Castroneves, Waile Ramadan Md, Domenico Salvatore, John W. Harney, Monica Dentice, Ann Marie Zavacki, J. Enrique Silva, Ana Luiza Maia, Simone Magagnin Wajner, Michelle A. Mulcahey, Iuri Martin Goemann, Alessandro Marsili, Stephen A. Huang

Publikováno v: Endocrinology. 151(12)

Because of its large mass, relatively high metabolic activity and responsiveness to thyroid hormone, skeletal muscle contributes significantly to energy expenditure. Despite the presence of mRNA encoding the type 2 iodothyronine-deiodinase (D2), an e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a464dc78c9e4ec6ee7c193df5c5036
https://pubmed.ncbi.nlm.nih.gov/20881246

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D3 Expression And Activation Are Increased In ARDS With Decreased Tissue T3 In Human Lungs

Autor: Stephen A. Huang, Timothy P. Rich, Thomas W. Bastian, Thomas J. Groppoli, Michelle A. Mulcahey, Grant W. Anderson, David H. Ingbar

Publikováno v: B29. GENETICS AND MOLECULAR MECHANISMS OF ACUTE LUNG INJURY.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20a765dc67af4d4ea8426db0b9fe8917
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2716

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Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells

Autor: Eva Sammels, Veerle Darras, Ann Marie Zavacki, Gert Van den Bergh, Michelle A. Mulcahey, Goele Aerts, Serge Van der Geyten, Balázs Gereben, Stijn Van Herck, Delphine Mirebeau-Prunier, Rafael Arrojo e Drigo, John W. Harney, Anikó Zeöld, Lut Arckens, Stephen A. Huang

Publikováno v: Endocrinology. 150(11)

The type 3 iodothyronine deiodinase (D3) is the primary deiodinase that inactivates thyroid hormone. Immunoprecipitation of D3, followed by fluorescent two-dimensional difference gel electrophoresis and mass spectrometry, identified peroxiredoxin 3 (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6a17da7b7dc8f82bc429c77220b06d
https://pubmed.ncbi.nlm.nih.gov/19819956

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THE THYROID HORMONE INACTIVATING DEIODINASE FUNCTIONS AS HOMODIMER

Autor: Cyntia Curcio-Morelli, Cristina Luongo, G. D.Vivek Sagar, Michelle A. Mulcahey, Stephen A. Huang, Isabelle Callebaut, John W. Harney, Jean-Paul Mornon, P. Reed Larsen, Balázs Gereben, Anikó Zeöld, Antonio C. Bianco

Publikováno v: Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2008, accepté. ⟨10.1210/me.2007-0490⟩
Molecular Endocrinology-Baltimore-, 2008, accepté. ⟨10.1210/me.2007-0490⟩

The type 3 deiodinase (D3) inactivates thyroid hormone action by catalyzing tissue-specific inner ring deiodination, predominantly during embryonic development. D3 has gained much attention as a player in the euthyroid sick syndrome, given its robust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c25db5c3da40b28d9c80b218cb0696
https://hal.archives-ouvertes.fr/hal-00266622

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