Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michelle A. Hartman"'
Autor:
Michelle L Hartman, Hardy Kornfeld
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27972 (2011)
A high intracellular bacillary load of Mycobacterium tuberculosis in macrophages induces an atypical lysosomal cell death with early features of apoptosis that progress to necrosis within hours. Unlike classical apoptosis, this cell death mode does n
Externí odkaz:
https://doaj.org/article/fe2f3f9629bc4f549c7055a77ff57431
Autor:
Crystal Jaing, Shea Gardner, Kevin McLoughlin, Nisha Mulakken, Michelle Alegria-Hartman, Phillip Banda, Peter Williams, Pauline Gu, Mark Wagner, Chitra Manohar, Tom Slezak
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2163 (2008)
Emerging known and unknown pathogens create profound threats to public health. Platforms for rapid detection and characterization of microbial agents are critically needed to prevent and respond to disease outbreaks. Available detection technologies
Externí odkaz:
https://doaj.org/article/e22c83e6c86a44558a049c5b58680793
Publikováno v:
FEBS Journal. 276:1915-1929
The mannose 6-phosphate/insulin-like growth factor II receptor has diverse ligand-binding properties contributing to its roles in lysosome biogenesis and growth suppression. Optimal receptor binding and internalization of mannose 6-phosphate (Man-6-P
Autor:
Santosh S. Arcot, Lesley Bennett, Prescott L. Deininger, David O. Nelson, Tamim H. Shaikh, Michelle Alegria-Hartman, Joomyeong Kim, Mark A. Batzer
Publikováno v:
Gene. 163:273-278
Members of the recently inserted human-specific (HS)/predicted variant (PV) subfamily of Alu elements were sequenced. A number of these Alu elements share greater than 98% sequence identity with the subfamily consensus sequence, and they are flanked
Dispersion and Insertion Polymorphism in Two Small Subfamilies of Recently Amplified HumanAluRepeats
Autor:
Mark A. Batzer, Esther P. Leeflang, Hernan A. Bazan, Carol M. Rubin, Carl W. Schmid, Michelle Alegria-Hartman, Joshua D. Stern, Prescott L. Deininger, Utha Hellmann-Blumberg, Tamim H. Shaikh
Publikováno v:
Journal of Molecular Biology. 247:418-427
Newly isolated members of two recently propagated (young) Alu subfamilies were examined for sequence diversity and insertion polymorphism in primate genomes. The smaller subfamily (termed HS-2) is comprised of approximately 5 to 25 members, while the
Autor:
W D Scheer, Gabriel E. Novick, Rene J. Herrera, David H. Kass, Michelle Alegria-Hartman, Mark A. Batzer, Tamim H. Shaikh, Mark Stoneking, Panayiotis A. Ioannou, Hernan A. Bazan
Publikováno v:
Proceedings of the National Academy of Sciences. 91:12288-12292
Alu elements are a family of interspersed repeats that have mobilized throughout primate genomes by retroposition from a few "master" genes. Among the 500,000 Alu elements in the human genome are members of the human-specific subfamily that are not f
Publikováno v:
Genetic Analysis: Biomolecular Engineering. 11:34-38
Physical mapping of the human genome involves a variety of complex hybridization-based procedures, some of which rely upon the ability to separate human clones derived from human-rodent hybrid cell lines from those that contain background rodent-deri
Autor:
Emma M. Creagh, Hardy Kornfeld, Amy O'Shea, Katherine A. Fitzgerald, Ed C. Lavelle, Shijuan Grace Zeng, Fiona A. Sharp, James Harris, Jürg Tschopp, Caitrionna Jane Roche, Douglas T. Golenbock, Eimear M Lambe, Michelle L Hartman
Autophagy is a key regulator of cellular homeostasis that can be activated by pathogen-associated molecules and recently has been shown to influence IL-1β secretion by macrophages. However, the mechanisms behind this are unclear. Here, we describe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bc019cc36c1e26f2a6f6473d1a1f2f
https://europepmc.org/articles/PMC3058966/
https://europepmc.org/articles/PMC3058966/
Autor:
Phillip Banda, Pauline Gu, Michelle Alegria-Hartman, Tom Slezak, Shea N. Gardner, Peter Williams, Chitra Manohar, Kevin McLoughlin, Nisha Mulakken, Crystal Jaing, Mark C. Wagner
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2163 (2008)
PLoS ONE
PLoS ONE
Emerging known and unknown pathogens create profound threats to public health. Platforms for rapid detection and characterization of microbial agents are critically needed to prevent and respond to disease outbreaks. Available detection technologies
Autor:
Michelle Alegria-Hartman, David O. Nelson, Todd H. Corzett, Kristin Robbins, Imola K. Fodor, Richard G. Langlois, Kenneth W. Turteltaub, Sandra L. McCutchen-Maloney
Publikováno v:
Bioinformatics (Oxford, England). 21(19)
Motivation: The DeCyder software (GE Healthcare) is the current state-of-the-art commercial product for the analysis of two-dimensional difference gel electrophoresis (2D DIGE) experiments. Analyses complementing DeCyder are suggested by incorporatin