Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle A. Bartholomew"'
Autor:
Bernhard Kerscher, Jillian L. Barlow, Batika M. Rana, Helen E. Jolin, Mayuri Gogoi, Michelle A. Bartholomew, Deepali Jhamb, Ashutosh Pandey, David F. Tough, Antoon J. M. van Oosterhout, Andrew N. J. McKenzie
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Group 2 innate lymphoid cells (ILC2) increase in frequency in eczema and allergic asthma patients, and thus represent a new therapeutic target cell for type-2 immune-mediated disease. The bromodomain and extra-terminal (BET) protein family of epigene
Externí odkaz:
https://doaj.org/article/cf45591004b94bc9b5c1e9eac52d646f
Autor:
Christopher R. Wellaway, Ian R. Baldwin, Paul Bamborough, Daniel Barker, Michelle A. Bartholomew, Chun-wa Chung, Birgit Dümpelfeld, John P. Evans, Neal J. Fazakerley, Paul Homes, Steven P. Keeling, Xiao Q. Lewell, Finlay W. McNab, Joanne Morley, Deborah Needham, Margarete Neu, Antoon J. M. van Oosterhout, Anshu Pal, Friedrich B. M. Reinhard, Francesco Rianjongdee, Craig M. Robertson, Paul Rowland, Rishi R. Shah, Emma B. Sherriff, Lisa A. Sloan, Simon Teague, Daniel A. Thomas, Natalie Wellaway, Justyna Wojno-Picon, James M. Woolven, Diane M. Coe
Publikováno v:
Journal of Medicinal Chemistry. 65:633-664
The Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and TYK2) play an essential role in the receptor signaling of cytokines that have been implicated in the pathogenesis of severe asthma, and there is emerging interest in the development of small
Autor:
Andrew N. J. McKenzie, Ashutosh K. Pandey, Deepali Jhamb, Bernhard Kerscher, Batika M. J. Rana, Mayuri Gogoi, Michelle Anne Bartholomew, Helen E. Jolin, Antoon J. M. van Oosterhout, Jillian L. Barlow, David F. Tough
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Group 2 innate lymphoid cells (ILC2) increase in frequency in eczema and allergic asthma patients, and thus represent a new therapeutic target cell for type-2 immune-mediated disease. The bromodomain and extra-terminal (BET) protein family of epigene
Autor:
Michelle L. Bartholomew, Sharon Wray
Publikováno v:
The International Journal of Aging and Society. 6:35-49
This article considers older international migrant women’s reflexive engagement with religion. The article is based on a sub-sample of data from an ESRC research study that set out to explore the ethnically diverse experiences of older women. In th
Autor:
Diane M. Coe, Andrei Mihut, Michelle Anne Bartholomew, Joanna M. Redmond, John P. Evans, Rishi R. Shah, John A. Murphy, Malini Menon
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115326
PROTACs have recently emerged as a novel paradigm in drug discovery. They can hijack existing biological machinery to selectively degrade proteins of interest, in a catalytic fashion. Here we describe the design, optimisation and biological activity
Autor:
Sharon Wray, Michelle L. Bartholomew
Publikováno v:
MIGRATION LETTERS. 7:7-16
This article explores some of the methodological issues relating to outsider and insider identities in ethnic and migrant qualitative research. It draws upon two qualitative research studies that set out to examine older (55-75 years) migrant African
Autor:
Peter H. Howarth, Pandurangan Vijayanand, Karl J. Staples, Michelle Anne Bartholomew, Kesta Durkin, Peter S. Friedmann, Grégory Seumois, Jaymin B. Morjaria, David A. Hall, Christina M. Bessant, Ratko Djukanovic, Guido Hartmann
Publikováno v:
The Journal of Immunology. 184:4568-4574
T lymphocytes of the Th2 type are central orchestrators of airway inflammation in asthma. The mechanisms that regulate their accumulation in the asthmatic airways remains poorly understood. We tested the hypothesis that CCR4, preferentially expressed