Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Michelle A. Hook"'
Autor:
Corinne E. Metzger, Robert C. Moore, Alexander S. Pirkle, Landon Y. Tak, Josephina Rau, Jessica A. Bryan, Alexander Stefanov, Matthew R. Allen, Michelle A. Hook
Publikováno v:
Bone Reports, Vol 21, Iss , Pp 101761- (2024)
Spinal cord injury (SCI) leads to significant sublesional bone loss and high fracture rates. While loss of mechanical loading plays a significant role in SCI-induced bone loss, animal studies have demonstrated mechanical loading alone does not fully
Externí odkaz:
https://doaj.org/article/5453a134865147b6a3e4a6e66d13a86f
Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury
Autor:
Mabel N. Terminel, Carla Bassil, Josephina Rau, Amanda Trevino, Cristina Ruiz, Robert Alaniz, Michelle A. Hook
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). However, morphine administration in the early phase of SCI undermines locomotor recovery, incr
Externí odkaz:
https://doaj.org/article/bba5874b543c42c892903b550b34cd87
Autor:
Corinne E, Metzger, Josephina, Rau, Alexander, Stefanov, Rose M, Joseph, Heather C M, Allaway, Matthew R, Allen, Michelle A, Hook
Publikováno v:
Journal of Neurotrauma. 40:901-917
Spinal cord injury (SCI) results in significant loss of sublesional bone, adding to the comorbidity of SCI with an increased risk of fracture and post-fracture complications. Unfortunately, the effect of SCI on skeletal health is also likely to rise,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6398a406c36b6b9cd8495e1ed76e28
https://doi.org/10.1089/neu.2022.0342
https://doi.org/10.1089/neu.2022.0342
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Spinal cord injury research in experimental animals aims to define mechanisms of tissue damage and identify interventions that can be translated into effective clinical therapies. Highly reliable models of injury and outcome measurement are essential
Externí odkaz:
https://doaj.org/article/6f4fb77dc2ad4094ad61d179ef7b8031
Autor:
Michelle A. Hook, Alyssa Falck, Ravali Dundumulla, Mabel Terminel, Rachel Cunningham, Arthur Sefiani, Kayla Callaway, Dana Gaddy, Cédric G. Geoffroy
Publikováno v:
Biology, Vol 11, Iss 2, p 189 (2022)
After spinal cord injury (SCI), 80% of individuals are diagnosed with osteopenia or osteoporosis. The dramatic loss of bone after SCI increases the potential for fractures 100-fold, with post-fracture complications occurring in 54% of cases. With the
Externí odkaz:
https://doaj.org/article/8de778be49974f218b42beea2b8bb319
Autor:
Josephina Rau, Annebel Hemphill, Kendall Araguz, Rachel Cunningham, Alexander Stefanov, Lara Weise, Michelle A. Hook
Publikováno v:
Journal of neurotrauma.
Immediately following spinal cord injury (SCI) patients experience pain associated with injury to the spinal cord and nerves as well as with accompanying peripheral injuries. This pain is usually treated with opioids, and most commonly with morphine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e903d90bd9a8a15b67e43ab0f945c3d3
https://pubmed.ncbi.nlm.nih.gov/35996351
https://pubmed.ncbi.nlm.nih.gov/35996351
Publikováno v:
IEEE Transactions on Biomedical Circuits and Systems. 15:326-338
Plantar cutaneous feedback plays an important role in stable and efficient gait, by modulating the activity of ankle dorsi- and plantar-flexor muscles. However, central and peripheral nervous system trauma often decrease plantar cutaneous feedback an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e704829b833e07ef564d72611c15d7
https://doi.org/10.1109/tbcas.2021.3072894
https://doi.org/10.1109/tbcas.2021.3072894
Autor:
Nihal A. Salem, Eric A Bancroft, Michelle A. Hook, Gauri Pandey, Brittany Cude, Sara M Zarate, Shannon Storey, Rahul Srinivasan, Jose A Garcia, Sunanda Chilukuri
Publikováno v:
J Neurochem
Apoptotic endoplasmic reticulum (ER) stress is a major mechanism for dopaminergic (DA) loss in Parkinson's disease (PD). We assessed if low doses of the partial α4β2 nicotinic acetylcholine receptor agonist, cytisine attenuates apoptotic ER stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7993657c68ce63490c4bfdb58d1d2c63
https://doi.org/10.1111/jnc.15282
https://doi.org/10.1111/jnc.15282
Autor:
Argyrios Stampas, Claudia Pedroza, Michelle A. Hook, Jennifer N. Bush, John L.K. Kramer, Adam R. Ferguson
Publikováno v:
Spinal Cord. 58:1080-1089
Retrospective chart review. The objective of this study was to characterize opioid administration in people with acute SCI and examine the association between opioid dose and (1) changes in motor/functional scores from hospital to rehabilitation disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d51ccd3b2d6ac914b738f218b2de1eb
https://doi.org/10.1038/s41393-020-0483-x
https://doi.org/10.1038/s41393-020-0483-x
Autor:
Mabel N. Terminel, Carla Bassil, Josephina Rau, Amanda Trevino, Cristina Ruiz, Robert Alaniz, Michelle A. Hook
Background Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). However, morphine administration in the early phase of SCI undermines locomotor recovery, increases cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f0e375092a792ac63f2521db6f7a2e7
https://doi.org/10.21203/rs.3.rs-1303819/v1
https://doi.org/10.21203/rs.3.rs-1303819/v1
