Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Michelle A Kelliher"'
Autor:
Amit K Pandey, Yibin Yang, Zhaozhao Jiang, Sarah M Fortune, Francois Coulombe, Marcel A Behr, Katherine A Fitzgerald, Christopher M Sassetti, Michelle A Kelliher
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000500 (2009)
While the recognition of microbial infection often occurs at the cell surface via Toll-like receptors, the cytosol of the cell is also under surveillance for microbial products that breach the cell membrane. An important outcome of cytosolic recognit
Externí odkaz:
https://doaj.org/article/50db0e43d14e43cf97950e9df7c26790
Autor:
Tianyi Ye, Alok K. Mishra, Shahid Banday, Rui Li, Kai Hu, Madison M. Coleman, Yi Shan, Shreya Roy Chowdhury, Lin Zhou, Magnolia L. Pak, Tessa M. Simone, Sunil K. Malonia, Lihua Julie Zhu, Michelle A. Kelliher, Michael R. Green
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114211- (2024)
Summary: Multiple myeloma (MM) remains an incurable hematological malignancy demanding innovative therapeutic strategies. Targeting MYC, the notorious yet traditionally undruggable oncogene, presents an appealing avenue. Here, using a genome-scale CR
Externí odkaz:
https://doaj.org/article/cbacef1a6c3c4564a194c75094fa53fc
Autor:
Alok K. Mishra, Tianyi Ye, Shahid Banday, Ritesh P. Thakare, Chinh Tran-To Su, Ngoc N.H. Pham, Amjad Ali, Ankur Kulshreshtha, Shreya Roy Chowdhury, Tessa M. Simone, Kai Hu, Lihua Julie Zhu, Birgit Eisenhaber, Sara K. Deibler, Karl Simin, Paul R. Thompson, Michelle A. Kelliher, Frank Eisenhaber, Sunil K. Malonia, Michael R. Green
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114041- (2024)
Summary: CD24 is frequently overexpressed in ovarian cancer and promotes immune evasion by interacting with its receptor Siglec10, present on tumor-associated macrophages, providing a “don’t eat me” signal that prevents targeting and phagocytos
Externí odkaz:
https://doaj.org/article/51c10ad4e53242b1b570a3e817e3e103
Publikováno v:
BioTech, Vol 13, Iss 3, p 30 (2024)
RNA sequencing (RNA-seq) has become a standard method for profiling gene expression, yet genomic DNA (gDNA) contamination carried over to the sequencing library poses a significant challenge to data integrity. Detecting and correcting this contaminat
Externí odkaz:
https://doaj.org/article/329f560b61cf4ce69837e9795689dd25
Autor:
Nicholas Chun, Rosalind L. Ang, Mark Chan, Robert L. Fairchild, William M. Baldwin III, Julian K. Horwitz, Jesse D. Gelles, Jerry Edward Chipuk, Michelle A. Kelliher, Vasile I. Pavlov, Yansui Li, Dirk Homann, Peter S. Heeger, Adrian T. Ting
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
TNF ligation of TNF receptor 1 (TNFR1) promotes either inflammation and cell survival by (a) inhibiting RIPK1’s death-signaling function and activating NF-κB or (b) causing RIPK1 to associate with the death-inducing signaling complex to initiate a
Externí odkaz:
https://doaj.org/article/1cef15809b5044ec872dc4819293a566
Publikováno v:
Trends in Immunology. 44:156-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5986bd017598f3226440a8d233bd7230
https://doi.org/10.1016/j.it.2023.01.009
https://doi.org/10.1016/j.it.2023.01.009
Supplementary Table 8 from TYK2–STAT1–BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
XLSX file - 24K, PCR Primer sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae008c7ad8c7be73a678ff7d8315a28b
https://doi.org/10.1158/2159-8290.22528985.v1
https://doi.org/10.1158/2159-8290.22528985.v1
Autor:
Anthony Letai, Michelle A. Kelliher, Alejandro Gutierrez, Marian Harris, Richard Stone, Daniel J. DeAngelo, Brent Wood, Stephen P. Hunger, Mignon L. Loh, Lewis B. Silverman, Stephen E. Sallan, Jeremy Ryan, Cian Glenfield, Justine E. Roderick, Triona Ni Chonghaile
NSG mice were injected in the tail with either ETP-ALL (TALL-x-11) or typical T-ALL (TALL-x-2) 1X106 cells and following engraftment to 65% the mice were randomized to receive vehicle, ABT-199 or ABT-263 treatment for two-weeks. The spleen weights (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420fd463af5ed6dbbe884834272bae70
https://doi.org/10.1158/2159-8290.22531948.v1
https://doi.org/10.1158/2159-8290.22531948.v1
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
PDF file - 113K, Bcl2 protein expression in wild-type and Tyk2 knockout mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ba7b281b9141533ece67a5eca0d6a5
https://doi.org/10.1158/2159-8290.22529012
https://doi.org/10.1158/2159-8290.22529012
Autor:
A. Thomas Look, Brian J. Druker, Louis M. Staudt, Andrew P. Weng, Catriona H.M. Jamieson, Nathanael S. Gray, Mathias Müller, Richard Moriggl, Ross L. Levine, Donna S. Neuberg, Michelle A. Kelliher, Jessica Tatarek, Yebin Ahn, Maria Kleppe, Yandan Yang, Wenjun Zhou, Angela G. Fleischman, Wenxue Ma, Arla Yost, Bill H. Chang, Jason Glover, Vu N. Ngo, Alejandro Gutierrez, Jeffrey W. Tyner, Takaomi Sanda
PDF file - 74K, Knockdown efficiency and BCL2 expression in JURKAT cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6781de9ba400c8ef69fbe3a4df74155e
https://doi.org/10.1158/2159-8290.22529027
https://doi.org/10.1158/2159-8290.22529027