Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Michelle, Willicombe"'
Publikováno v:
Transplant International, Vol 37 (2024)
Angiotensin II type-1 receptor antibody (AT1R-Ab) has been mooted as a potential effector of both acute and chronic antibody mediated rejection (AMR). A growing body of literature on the topic is now coming under scrutiny in the context of the evolvi
Externí odkaz:
https://doaj.org/article/32c1f2f59d094a1dacd39e745adfda02
Autor:
Jack S. Gisby, Norzawani B. Buang, Artemis Papadaki, Candice L. Clarke, Talat H. Malik, Nicholas Medjeral-Thomas, Damiola Pinheiro, Paige M. Mortimer, Shanice Lewis, Eleanor Sandhu, Stephen P. McAdoo, Maria F. Prendecki, Michelle Willicombe, Matthew C. Pickering, Marina Botto, David C. Thomas, James E. Peters
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
End-stage kidney disease confers a high risk for severe COVID-19 infection. Using an at-risk group (end-stage kidney disease patients with COVID-19), authors using RNA-sequencing of immune cells and plasma proteomic profiling to investigate the host
Externí odkaz:
https://doaj.org/article/6195c991b86743c2bc2cea16ffcb650a
Autor:
Sevda Hassan, Lisa Mumford, Susan Robinson, Dora Foukanelli, Nick Torpey, Rutger J. Ploeg, Nizam Mamode, Michael F. Murphy, Colin Brown, David J. Roberts, Fiona Regan, Michelle Willicombe
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
BackgroundPatient Blood Management (PBM), endorsed by the World Health Organisation is an evidence-based, multi-disciplinary approach to minimise inappropriate blood product transfusions. Kidney transplantation presents a particular challenge to PBM,
Externí odkaz:
https://doaj.org/article/d52319a301af444e911fac7f8425e290
Autor:
Sevda Hassan, Sarah Gleeson, Tina Thomson, Katrina J. Spensley, Frank Dor, Colin Brown, Fiona Regan, Liset H. M. Pengel, Michelle Willicombe, David J. Roberts
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionRed blood cell transfusions (RBCT) represent a potentially modifiable risk factor for HLA sensitisation and adverse outcomes post transplantation. Evidence of the clinical impact of post-transplant RBCT has been infrequently reported. Her
Externí odkaz:
https://doaj.org/article/d4f1a013299e45b68d0abdd523196d8d
Autor:
Amarpreet K. Thind, Annabel Rule, Dawn Goodall, Shuli Levy, Sarah Brice, Frank J. M. F. Dor, Nicola Evans, David Ospalla, Nicola Thomas, David Wellsted, Lina Johansson, Michelle Willicombe, Edwina A. Brown
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Kidney transplantation in older people has increased, however older transplant recipients experience mixed outcomes that invariably impacts on their quality of life. The increased vulnerability of older end stage kidney disease pa
Externí odkaz:
https://doaj.org/article/3058931262a04928844de9f68fc7bd0d
Autor:
Shenzhen Tempest-Roe, Maria Prendecki, Stephen P. McAdoo, Candice Clarke, Anisha Tanna, Tabitha Turner-Stokes, Esteban S. Masuda, Michelle Willicombe, H. Terence Cook, Candice Roufosse, David Taube, Charles D. Pusey, Frederick W. K. Tam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antibody mediated rejection is a major cause of renal allograft loss. Circulating preformed donor specific antibodies (DSA) can result as a consequence of blood transfusion, pregnancy or prior transplantation. Current treatment strategies ar
Externí odkaz:
https://doaj.org/article/657abd7f4c754b5aa4ed59b73337583f
Autor:
Ben Goldacre, Sam Harper, Alex J Walker, William J Hulme, Dorothea Nitsch, Laurie A Tomlinson, Bang Zheng, Helen J Curtis, Amir Mehrkar, Jonathan Cockburn, John Parry, Frank Hester, Retha Steenkamp, Elizabeth J Williamson, Shalini Santhakumaran, Jonathan AC Sterne, John Tazare, Michelle Willicombe, Fiona Loud, Viyaasan Mahalingasivam, Louis Fisher, Linda Nab, Christopher Bates, Edward PK Parker, Edward J Carr, Amelia CA Green, Elsie MF Horne, Susan Lyon
Publikováno v:
BMJ Open, Vol 13, Iss 1 (2023)
Objective To characterise factors associated with COVID-19 vaccine uptake among people with kidney disease in England.Design Retrospective cohort study using the OpenSAFELY-TPP platform, performed with the approval of NHS England.Setting Individual-l
Externí odkaz:
https://doaj.org/article/d5c90c1c59604401918c9f432f3d4164
Publikováno v:
Frontiers in Nephrology, Vol 2 (2023)
BackgroundOlder people with end-stage kidney disease (ESKD) are vulnerable to frailty, which impacts on clinical and experiential outcomes. With kidney transplantation in older people increasing, a better understanding of patient experiences is neces
Externí odkaz:
https://doaj.org/article/f537fc43a45f4b4c8f9405ae1bb35b9c
Autor:
Sarah Gleeson, Paul Martin, Tina Thomson, Katrina J. Spensley, Dawn Goodall, Rachna Bedi, Amarpreet Kaur Thind, Charlotte Seneschall, Jaslyn Gan, Stephen McAdoo, Liz Lightstone, Peter Kelleher, Maria Prendecki, Michelle Willicombe
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
SARS-CoV-2 vaccines are recommended pre-transplantation, however, waning immunity and evolving variants mandate booster doses. Currently there no data to inform the optimal timing of booster doses post-transplant, in patients primed pre-transplant. W
Externí odkaz:
https://doaj.org/article/c103d95d4bed4b4dadf29c874a37276e
Autor:
Tina Thomson, Maria Prendecki, Sarah Gleeson, Paul Martin, Katrina Spensley, Rute Cardoso De Aguiar, Bynvant Sandhu, Charlotte Seneschall, Jaslyn Gan, Candice L. Clarke, Shanice Lewis, Graham Pickard, David Thomas, Stephen P. McAdoo, Liz Lightstone, Alison Cox, Peter Kelleher, Michelle Willicombe
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101642- (2022)
Summary: Background: Solid organ transplant recipients have attenuated immune responses to SARS-CoV-2 vaccines. In this study, we report on immune responses to 3rd- (V3) and 4th- (V4) doses of heterologous and homologous vaccines in a kidney transpla
Externí odkaz:
https://doaj.org/article/4879b50c9f754096b64b6ff9caf5fbc2