Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michelle, Nilsson"'
Publikováno v:
Biophysical Journal. 122:310a-311a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50ffefb5c790a0b08cb7a2587bf7142
https://doi.org/10.1016/j.bpj.2022.11.1745
https://doi.org/10.1016/j.bpj.2022.11.1745
Autor:
Michelle, Nilsson, Sarah H, Lindström, Maki, Kaneko, Kaiqian, Wang, Teresa, Minguez-Viñas, Marina, Angelini, Federica, Steccanella, Deborah, Holder, Michela, Ottolia, Riccardo, Olcese, Antonios, Pantazis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(17)
We report on a heterozygous KCNA2 variant in a child with epilepsy. KCNA2 encodes KV1.2 subunits, which form homotetrameric potassium channels and participate in heterotetrameric channel complexes with other KV1-family subunits, regulating neuronal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0708e9176527c83c310a90c770b7567f
https://pubmed.ncbi.nlm.nih.gov/35439054
https://pubmed.ncbi.nlm.nih.gov/35439054
Autor:
Maki Kaneko, Lucie Delemotte, Antonios Pantazis, Sulagna C. Saitta, Marina Angelini, Federica Steccanella, Sarah H. Lindstrom, Riccardo Olcese, Annie M. Westerlund, Michelle Nilsson
Publikováno v:
The Journal of Physiology. 598:5245-5269
KEY POINTS KV 1.2 channels, encoded by the KCNA2 gene, regulate neuronal excitability by conducting K+ upon depolarization. A new KCNA2 missense variant was discovered in a patient with epilepsy, causing amino acid substitution F302L at helix S4, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::854bfaf78db77703da057546c194b6f5
https://doi.org/10.1113/jp280438
https://doi.org/10.1113/jp280438
Publikováno v:
Biophysical Journal. 122:104a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cc1dbadbbd0a7087c9c8354fa6975d7
https://doi.org/10.1016/j.bpj.2022.11.749
https://doi.org/10.1016/j.bpj.2022.11.749
Autor:
Nina E, Ottosson, Malin, Silverå Ejneby, Xiongyu, Wu, Argel, Estrada-Mondragón, Michelle, Nilsson, Urban, Karlsson, Melanie, Schupp, Salomé, Rognant, Thomas Andrew, Jepps, Peter, Konradsson, Fredrik, Elinder
Publikováno v:
EpilepsiaREFERENCES. 62(7)
About one third of all patients with epilepsy have pharmacoresistant seizures. Thus there is a need for better pharmacological treatments. The human voltage-gated potassium (hKIon channels were expressed in Xenopus oocytes or mammalian cell lines and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dea4348710abf810491400b825565ccf
https://pubmed.ncbi.nlm.nih.gov/34085706
https://pubmed.ncbi.nlm.nih.gov/34085706
Autor:
Peter Konradsson, Michelle Nilsson, Malin Silverå Ejneby, Xiongyu Wu, Thomas A. Jepps, Urban Karlsson, Argel Estrada-Mondragón, Fredrik Elinder, Salomé Rognant, Melanie Schupp, Nina E. Ottosson
Publikováno v:
Ottosson, N E, Ejneby, M S, Wu, X, Estrada-Mondragon, A, Nilsson, M, Karlsson, U, Schupp, M, Rognant, S, Jepps, T A, Konradsson, P & Elinder, F 2021, ' Synthetic resin acid derivatives selectively open the hK(V)7.2/7.3 channel and prevent epileptic seizures ', Epilepsia, vol. 62, no. 7, pp. 1744-1758 . https://doi.org/10.1111/epi.16932
Objective About one third of all patients with epilepsy have pharmacoresistant seizures. Thus there is a need for better pharmacological treatments. The human voltage-gated potassium (hK(V)) channel hK(V)7.2/7.3 is a validated antiseizure target for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b80e815713c1101190996e21db2cc8
https://curis.ku.dk/ws/files/272246120/Synthetic_resin_acid_derivatives_selectively_open.pdf
https://curis.ku.dk/ws/files/272246120/Synthetic_resin_acid_derivatives_selectively_open.pdf
Autor:
Antonios, Pantazis, Maki, Kaneko, Marina, Angelini, Federica, Steccanella, Annie M, Westerlund, Sarah H, Lindström, Michelle, Nilsson, Lucie, Delemotte, Sulagna C, Saitta, Riccardo, Olcese
Publikováno v:
J Physiol
An exome-based diagnostic panel in an infant with epilepsy revealed a previously unreported de novo missense variant in KCNA2, which encodes voltage-gated K(+) channel K(V)1.2. This variant causes substitution F302L, in helix S4 of the K(V)1.2 voltag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b833116bb6cbc340383374702a8866f6
https://pubmed.ncbi.nlm.nih.gov/32833227
https://pubmed.ncbi.nlm.nih.gov/32833227
Autor:
Michelle Nilsson, Sarah H. Lindström, Maki Kaneko, Kaiqian Wang, Teresa Minguez Vinas, Marina Angelini, Federica Steccanella, Deborah Holder, Michela Ottolia, Riccardo Olcese, Antonios Pantazis
Publikováno v:
Biophysical Journal. 121:390a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a38a93c2ac2aa20b4f00662b5cb88e7
https://doi.org/10.1016/j.bpj.2021.11.811
https://doi.org/10.1016/j.bpj.2021.11.811
Autor:
Riccardo Olcese, Marina Angelini, Michelle Nilsson, Deborah Holder, Michela Ottolia, Antonios Pantazis, Federica Steccanella, Sarah H. Lindstrom, Maki Kaneko
Publikováno v:
Biophysical Journal. 120:288a-289a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b9903490be51fa5d054b9a4ab63cba
https://doi.org/10.1016/j.bpj.2020.11.1849
https://doi.org/10.1016/j.bpj.2020.11.1849
Autor:
Xiongyu Wu, Fredrik Elinder, Malin Silverå Ejneby, Melanie Schupp, Peter Konradsson, Nina E. Ottosson, Urban Karlsson, Michelle Nilsson
Publikováno v:
Biophysical Journal. 118:264a-265a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de3c0c7c2e15671ace80579866e0a313
https://doi.org/10.1016/j.bpj.2019.11.1531
https://doi.org/10.1016/j.bpj.2019.11.1531