Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michelle, Kuzma"'
Autor:
Vijaya L. Damaraju, Maral Aminpour, Michelle Kuzma, Philip Winter, Jordane Preto, Jack Tuszynski, Alexander B.J. McEwan, Michael B. Sawyer
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 847-858 (2021)
Positron emission tomography (PET) using 2‐deoxy‐2‐[18F]fluoro‐d‐glucose ([18F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growt
Externí odkaz:
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
Autor:
Jack A. Tuszynski, Michael B. Sawyer, Vijaya L. Damaraju, Philip Winter, Jordane Preto, Alexander B.J. McEwan, Maral Aminpour, Michelle Kuzma
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 847-858 (2021)
Positron emission tomography (PET) using 2-deoxy-2-[18 F]fluoro-d-glucose ([18 F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be13eae69e629421eb604d42b7b91acc
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
https://doaj.org/article/0ee71f90bba14c2d88d2155aa4242963
Autor:
Vijaya L, Damaraju, Maral, Aminpour, Michelle, Kuzma, Philip, Winter, Jordane, Preto, Jack, Tuszynski, Alexander B J, McEwan, Michael B, Sawyer
Publikováno v:
Clinical and Translational Science
Positron emission tomography (PET) using 2‐deoxy‐2‐[18F]fluoro‐d‐glucose ([18F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba771999241a73038912720f62827bfe
https://pubmed.ncbi.nlm.nih.gov/33278334
https://pubmed.ncbi.nlm.nih.gov/33278334
Publikováno v:
Biochemical Pharmacology. 155:162-171
Tyrosine kinase inhibitors (TKIs) have advanced cancer treatment and prognosis but have also resulted in adverse effects such as fatigue, diarrhea, hypothyroidism, and other toxicities. We investigated TKI effects on skeletal muscle as a possible exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d76bafe7363028facba2acb584107d5
https://doi.org/10.1016/j.bcp.2018.07.001
https://doi.org/10.1016/j.bcp.2018.07.001
Publikováno v:
Journal of Biological Chemistry. 291:18809-18817
Human nucleoside transporters (hNTs) mediate cellular influx of anticancer nucleoside drugs, including cytarabine, cladribine, and fludarabine. BCR-ABL tyrosine kinase inhibitors (TKIs) imatinib and dasatinib inhibit fludarabine and cytarabine uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bfc23e0a152203b184ce8f67fde99f
https://doi.org/10.1074/jbc.m116.741074
https://doi.org/10.1074/jbc.m116.741074
Publikováno v:
Cancer Chemotherapy and Pharmacology. 76:1093-1098
Effects of tyrosine kinase inhibitors (TKIs) on equilibrative nucleobase transport (ENBT) and sodium-dependent nucleobase transport (SNBT) activities were investigated in normal human renal proximal tubule epithelial cells (hRPTECs) and in pig kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d9e954f7c6f7eaf1888ce04eaf6c9b
https://doi.org/10.1007/s00280-015-2859-8
https://doi.org/10.1007/s00280-015-2859-8
Autor:
Michelle Kuzma, Anderson J. Ryan, Carol E. Cass, Tara Scriver, Delores Mowles, Michael B. Sawyer, Vijaya L. Damaraju
Publikováno v:
Clinical Cancer Research. 20:176-186
Purpose: Combinations of tyrosine kinase inhibitors (TKI) with gemcitabine have been attempted with little added benefit to patients. We hypothesized that TKIs designed to bind to ATP-binding pockets of growth factor receptors also bind to transporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61aff54f02549dec30791b53889f025d
https://doi.org/10.1158/1078-0432.ccr-13-2293
https://doi.org/10.1158/1078-0432.ccr-13-2293
Autor:
Michelle Kuzma, Carol E. Cass, Vijaya L. Damaraju, Marnie Wilson, Michael B. Sawyer, Delores Mowles
Publikováno v:
Biochemistry and Cell Biology. 91:419-427
The goal of this study was to understand roles of nucleoside and nucleobase transport processes in capecitabine pharmacology in cells derived from human renal proximal tubule cells (hRPTCs) and three human renal cell carcinoma (RCC) cell lines, A498,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b5fa0adc42e779370dd9675e8d9246
https://doi.org/10.1139/bcb-2013-0041
https://doi.org/10.1139/bcb-2013-0041
Publikováno v:
The Journal of biological chemistry. 291(36)
Human nucleoside transporters (hNTs) mediate cellular influx of anticancer nucleoside drugs, including cytarabine, cladribine, and fludarabine. BCR-ABL tyrosine kinase inhibitors (TKIs) imatinib and dasatinib inhibit fludarabine and cytarabine uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e73d5e184ceaf9b32f82a9799b6ef84b
https://pubmed.ncbi.nlm.nih.gov/27432881
https://pubmed.ncbi.nlm.nih.gov/27432881
Autor:
Vickie E. Baracos, Vijaya L. Damaraju, Linda J. McCargar, Tony Reiman, Michelle Kuzma, Carla M. Prado, Michael B. Sawyer, John R. Mackey, Isac S. F. Lima, Robert R. Bies
Publikováno v:
Cancer Chemotherapy and Pharmacology. 67:93-101
Although body composition has emerged as an important predictor of drug efficacy and toxicity, explanations for this association are unclear. Our goal was to investigate relationships between lean body mass (LBM), liver size/function and epirubicin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96e68977999f5e21d88ad5c9605657a
https://doi.org/10.1007/s00280-010-1288-y
https://doi.org/10.1007/s00280-010-1288-y