Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michell M Reimer"'
Autor:
Jamie McQueen, Michell M Reimer, Philip R Holland, Yasmina Manso, Mark McLaughlin, Jill H Fowler, Karen Horsburgh
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87227 (2014)
Chronic cerebral hypoperfusion, a sustained modest reduction in cerebral blood flow, is associated with damage to myelinated axons and cognitive decline with ageing. Oligodendrocytes (the myelin producing cells) and their precursor cells (OPCs) may b
Externí odkaz:
https://doaj.org/article/2cb44815c5c14670820d6e19fbe5aa82
Autor:
Lydia Reinhardt, Susanne Kordes, Peter Reinhardt, Michael Glatza, Matthias Baumann, Hannes C.A. Drexler, Sascha Menninger, Gunther Zischinsky, Jan Eickhoff, Claudia Fröb, Prabesh Bhattarai, Guruchandar Arulmozhivarman, Lara Marrone, Antje Janosch, Kenjiro Adachi, Martin Stehling, Eric N. Anderson, Masin Abo-Rady, Marc Bickle, Udai Bhan Pandey, Michell M. Reimer, Caghan Kizil, Hans R. Schöler, Peter Nussbaumer, Bert Klebl, Jared L. Sterneckert
Publikováno v:
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Summary: Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neu
Externí odkaz:
https://doaj.org/article/d6324808720f45358bb83abf2c104f0a
Autor:
Daniel Wehner, Themistoklis M. Tsarouchas, Andria Michael, Christa Haase, Gilbert Weidinger, Michell M. Reimer, Thomas Becker, Catherina G. Becker
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Following spinal injury in zebrafish, non-neural cells establish an extracellular matrix to promote axon re-growth but how this is regulated is unclear. Here, the authors show that Wnt/β-catenin signaling in fibroblast-like cells at a lesion activat
Externí odkaz:
https://doaj.org/article/c3ca8d8280e24c85b351e0dcdd875413
Autor:
Vasiliki Tsata, Volker Kroehne, Susanne Reinhardt, Ali El-Armouche, Michael Brand, Michael Wagner, Michell M. Reimer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Low remyelination efficiency after spinal cord injury (SCI) is a major restraint to successful axonal and functional regeneration in mammals. In contrast, adult zebrafish can: (i) regenerate oligodendrocytes and myelin sheaths within 2 weeks post les
Externí odkaz:
https://doaj.org/article/1122657f38e2401c8eb874a7d877775b
Autor:
Antón Barreiro-Iglesias, Karolina S. Mysiak, Angela L. Scott, Michell M. Reimer, Yujie Yang (杨宇婕), Catherina G. Becker, Thomas Becker
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 924-932 (2015)
In contrast to mammals, zebrafish regenerate spinal motor neurons. During regeneration, developmental signals are re-deployed. Here, we show that, during development, diffuse serotonin promotes spinal motor neuron generation from pMN progenitor cells
Externí odkaz:
https://doaj.org/article/888bb4194ec4419c8d207364770b5d58
Autor:
Michael Brand, Thomas Kurth, Markus Loeffler, Christian Lange, Michell M. Reimer, Fabian Rost, Daniel Wehner, Cornelia Hoppe, Volker Kroehne, Susanne Reinhardt, Vasiliki Tsata, Andreas Dahl, Andreas Petzold
Publikováno v:
Development (Cambridge, England). 147(24)
Spinal cord injury (SCI) results in loss of neurons, oligodendrocytes and myelin sheaths, all of which are not efficiently restored. The scarcity of oligodendrocytes in the lesion site impairs re-myelination of spared fibres, which leaves axons denud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0725bfae90c5d7472d99c9165a845a04
https://pubmed.ncbi.nlm.nih.gov/33158923
https://pubmed.ncbi.nlm.nih.gov/33158923
Autor:
Bert Klebl, Martin Stehling, Lara Marrone, Peter Nussbaumer, Masin Abo-Rady, Antje Janosch, Jan Eickhoff, Matthias Baumann, Eric N. Anderson, Guruchandar Arulmozhivarman, Gunther Zischinsky, Kenjiro Adachi, Sascha Menninger, Marc Bickle, Peter Reinhardt, Claudia Fröb, Hannes C.A. Drexler, Michell M. Reimer, Jared Sterneckert, Michael Glatza, Susanne Kordes, Prabesh Bhattarai, Udai Bhan Pandey, Caghan Kizil, Lydia Reinhardt, Hans R. Schöler
Publikováno v:
Stem Cell Reports
Stem cell reports 12(3), 502-517 (2019). doi:10.1016/j.stemcr.2019.01.015
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Stem cell reports 12(3), 502-517 (2019). doi:10.1016/j.stemcr.2019.01.015
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Summary Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a62262d3eda3ad763fb4978fc17dde
Autor:
Thomas Becker, Antón Barreiro-Iglesias, Michell M. Reimer, Karolina S. Mysiak, Catherina G. Becker, Yujie Yang, Angela L. M. Scott
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 924-932 (2015)
Cell Reports
Barreiro-Iglesias, A, Mysiak, K S, Scott, A L, Reimer, M M, Yang, Y, Becker, C G & Becker, T 2015, ' Serotonin promotes development and regeneration of spinal motor neurons in zebrafish ', Cell Reports, vol. 13, no. 5, pp. 924-932 . https://doi.org/10.1016/j.celrep.2015.09.050
Cell Reports
Barreiro-Iglesias, A, Mysiak, K S, Scott, A L, Reimer, M M, Yang, Y, Becker, C G & Becker, T 2015, ' Serotonin promotes development and regeneration of spinal motor neurons in zebrafish ', Cell Reports, vol. 13, no. 5, pp. 924-932 . https://doi.org/10.1016/j.celrep.2015.09.050
Summary In contrast to mammals, zebrafish regenerate spinal motor neurons. During regeneration, developmental signals are re-deployed. Here, we show that, during development, diffuse serotonin promotes spinal motor neuron generation from pMN progenit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0f79b17e0f783025856a17232471ee
http://www.sciencedirect.com/science/article/pii/S221112471501075X
http://www.sciencedirect.com/science/article/pii/S221112471501075X
Autor:
Volker Kroehne, Vasiliki Tsata, Lara Marrone, Claudia Froeb, Susanne Reinhardt, Anne Gompf, Andreas Dahl, Jared Sterneckert, Michell M. Reimer
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Endogenous oligodendrocyte progenitor cells (OPCs) are a promising target to improve functional recovery after spinal cord injury (SCI) by remyelinating denuded, and therefore vulnerable, axons. Demyelination is the result of a primary insult and sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136d27063935789c9fea0a43003cdb98
https://doi.org/10.3389/fncel.2017.00284
https://doi.org/10.3389/fncel.2017.00284
Autor:
Rickie Patani, Zhen Zhong, Pertti Panula, Jochen Ohnmacht, E. Elizabeth Patton, Anneliese Norris, Veronika Kuscha, Michell M. Reimer, Sarah Louise Frazer, Cameron Wyatt, Thomas Becker, Shin-ichi Higashijima, Siddharthan Chandran, Yu-Chia Chen, Angela L. M. Scott, S. V. Rozov, Tatyana B. Dias, Catherina G. Becker
Publikováno v:
Developmental Cell, 25(5), 478-491. Elsevier Science (2013).
SummaryCoordinated development of brain stem and spinal target neurons is pivotal for the emergence of a precisely functioning locomotor system. Signals that match the development of these far-apart regions of the central nervous system may be redepl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed328f994d57813ae057c6b75a9b440
https://doi.org/10.1016/j.devcel.2013.04.012
https://doi.org/10.1016/j.devcel.2013.04.012