Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Micheline Federman"'
Autor:
Sidney Levitsky, James D. McCully, Julia Thom Oxford, Mohamad Navab, Constantine E. Anagnostopoulos, Themistocles P. Chamogeorgakis, Maria Ericsson, Richard J. Shemin, Micheline Federman, Douglas B. Cowan, Chris K. Rokkas, Ioannis K. Toumpoulis, Dimitrios C. Angouras
Publikováno v:
The Annals of Thoracic Surgery. 88:506-513
The molecular mechanisms leading to ascending thoracic aortic aneurysms (ATAAs) remain unknown. We hypothesized that alterations in expression levels of specific fibrillar collagens occur during the aneurysmal process.Surgical samples from ascending
Autor:
James D. McCully, Bradford M. Stadler, Sidney Levitsky, Jonathan A. Phillips, Micheline Federman, Yoshiya Toyoda
Publikováno v:
The Annals of Thoracic Surgery. 72:555-563
Adenosine-enhanced ischemic preconditioning extends the protection of ischemic preconditioning by both significantly decreasing infarct size and significantly enhancing postischemic functional recovery.The effects of adenosine-enhanced ischemic preco
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 112(1):175-184
Objective: The effect of cardioplegic solutions with high concentrations of potassium or magnesium (or both) on cytosolic calcium accumulation was investigated with fura-2 in isolated perfused mature (n = 24) and aged (n = 24) rabbit hearts. Methods:
Autor:
Elizabeth A. Faulk, Narelle C. Hadlow, Irvin B. Krukenkamp, Takuro Tsukube, Sidney Levitsky, James D. McCully, Micheline Federman
Publikováno v:
Circulation. 92:405-412
Background The aged myocardium accumulates significantly more cytosolic calcium [Ca 2+ ] i during ischemia, and functional recovery is more severely compromised as compared with the mature heart. Cardioplegia ameliorates these phenomena. The mechanis
Autor:
Micheline Federman, Geoffrey H. Tofler, Otavio Gebara, Paulo D. Picon, George S. Abela, Akira Miyamoto, James E. Muller, Stephan E. Friedl
Publikováno v:
Circulation. 91:776-784
Background It is now recognized that plaque disruption and thrombosis, a process often triggered by activities of the patient, is generally the cause of the onset of acute coronary syndromes. Understanding of disease onset could be greatly enhanced b
Publikováno v:
Ultrastructural Pathology. 17:593-598
Intracytoplasmic inclusion bodies with an unusual immunohistochemical profile, histologically similar to alpha 1 antitrypsin globules and megamitochondria, were seen within hepatocytes in a liver allograft biopsy. Electron microscopy revealed that th
Autor:
Manjula Bansal, Barbara D. Boyan, Micheline Federman, Clare M. Rimnac, Adele L. Boskey, Jane B. Lian
Publikováno v:
Journal of Orthopaedic Research. 10:774-783
Magnesium is known to have an essential role in determining the properties of bone, but the way in which Mg exerts its actions remains unclear. Although long-term Mg deficiency is known to produce osteopenia, the effects of short-term Mg deficiency h
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 287(5)
Previously, we have shown that the pharmacological opening of the mitochondrial ATP-sensitive K channels with diazoxide (DZX) enhances the cardioprotection afforded by magnesium-supplemented potassium (K/Mg) cardioplegia. To determine the mechanisms
Autor:
Sidney Levitsky, Robert A. Parker, Douglas B. Cowan, James D. McCully, Hidetaka Wakiyama, Micheline Federman
Publikováno v:
The Annals of thoracic surgery. 74(6)
Recently, we have shown that the selective opening of mitochondrial ATP-sensitive potassium channels with diazoxide significantly decreases myocardial injury. The purpose of this study was to determine the effects of diazoxide on apoptosis and the me
Autor:
Thomas S. Thornhill, John J. Godleski, Myron Spector, Benjamin E. Bierbaum, Micheline Federman, Eric B. Benz
Publikováno v:
Biomaterials. 22(21)
The objectives of this transmission electron microscopy study of peri-implant tissues retrieved at revision arthroplasty were to (1) determine the size distribution of intracellular polyethylene particles, and (2) assess the cellular response to phag