Magnetic nanoparticle hyperthermia for treating locally advanced unresectable and borderline resectable pancreatic cancers: the role of tumor size and eddy-current heating

Autor: Haoming Zhou, Theodore L. DeWeese, Michele Wabler, Anilchandra Attaluri, Sri Kamal Kandala, Robert Ivkov

Publikováno v: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
International Journal of Hyperthermia, Vol 37, Iss 3, Pp 108-119 (2020)

Purpose: Tumor volume largely determines the success of local control of borderline resectable and locally advanced pancreatic cancer with current therapy. We hypothesized that a tumor-mass normalized dose of magnetic nanoparticle hyperthermia (MNPH)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea9b509ff182ab0242e27c1f54f4bcd
https://pubmed.ncbi.nlm.nih.gov/33426990

An optimised spectrophotometric assay for convenient and accurate quantitation of intracellular iron from iron oxide nanoparticles

Autor: Michele Wabler, Haoming Zhou, Arsalan Nejad, Mohammad Hedayati, Robert Ivkov, Cordula Gruettner, Allen Razavi, Jana N. Mihalic, Isa Mohammed, Theodore L. DeWeese, Mohamed H. Khattab, Bedri Abubaker-Sharif

Publikováno v: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

We report the development and optimisation of an assay for quantitating iron from iron oxide nanoparticles in biological matrices by using ferene-s, a chromogenic compound. The method is accurate, reliable and can be performed with basic equipment co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e34580bee0e443c045983ffcdad712
https://pubmed.ncbi.nlm.nih.gov/28758530

Magnetic nanoparticle hyperthermia enhances radiation therapy: A study in mouse models of human prostate cancer

Autor: Cila Herman, Christine Cornejo, Anilchandra Attaluri, Haoming Zhou, Theodore L. DeWeese, Mohammad Hedayati, Sri Kamal Kandala, Robert Ivkov, Michael Armour, Yonggang Zhang, Michele Wabler

We aimed to characterise magnetic nanoparticle hyperthermia (mNPH) with radiation therapy (RT) for prostate cancer.Human prostate cancer subcutaneous tumours, PC3 and LAPC-4, were grown in nude male mice. When tumours measured 150 mm3 magnetic iron o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ef4b84857cfd85c53807371bc740e1
https://europepmc.org/articles/PMC4696027/

Characterization of intratumor magnetic nanoparticle distribution and heating in a rat model of metastatic spine disease

Autor: Patricia L, Zadnik, Camilo A, Molina, Rachel, Sarabia-Estrada, Mari L, Groves, Michele, Wabler, Jana, Mihalic, Edward F, McCarthy, Ziya L, Gokaslan, Robert, Ivkov, Daniel, Sciubba

Publikováno v: Journal of neurosurgery. Spine. 20(6)

The goal of this study was to optimize local delivery of magnetic nanoparticles in a rat model of metastatic breast cancer in the spine for tumor hyperthermia while minimizing systemic exposure.A syngeneic mammary adenocarcinoma was implanted into th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37ce6e3fe983dd6a7b9836ef4cb3a86f
https://pubmed.ncbi.nlm.nih.gov/24702509

Calibration of a Quasi-Adiabatic Magneto-Thermal Calorimeter Used to Characterize Magnetic Nanoparticle Heating

Autor: Michele Wabler, Anilchandra Attaluri, Robert Ivkov, Charlie Nusbaum

Publikováno v: Journal of Nanotechnology in Engineering and Medicine. 4

To assess and validate temperature measurement and data analysis techniques for a quasi-adiabatic calorimeter used to measure amplitude-dependent loss power of magnetic nanoparticles exposed to an alternating magnetic field (AMF) at radiofrequencies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a36d99dd34085f08f66d3911afa6f0a
https://doi.org/10.1115/1.4024273