Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michele T, Hu"'
Autor:
Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met
Externí odkaz:
https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9
Autor:
Maria Bălăeţ, Falah Alhajraf, Niall J. Bourke, Jessica Welch, Jamil Razzaque, Paresh Malhotra, Michele T. Hu, Adam Hampshire
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundMetacognition is the ability to monitor and self-assess cognitive performance. It can be impaired in neurodegenerative diseases, with implications for daily function, and the ability of patients to reliably report their symptoms to health p
Externí odkaz:
https://doaj.org/article/b416828297a646b0aadeb2b42a1a3445
Publikováno v:
BioMedical Engineering OnLine, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Freezing-of-gait (FOG) and impaired walking are common features of Parkinson’s disease (PD). Provision of external stimuli (cueing) can improve gait, however, many cueing methods are simplistic, increase task loading or have limited utilit
Externí odkaz:
https://doaj.org/article/86a3b8c749244ed4969748380b81b8c1
Autor:
Cynthia Sandor, Stephanie Millin, Andrew Dahl, Ann-Kathrin Schalkamp, Michael Lawton, Leon Hubbard, Nabila Rahman, Nigel Williams, Yoav Ben-Shlomo, Donald G. Grosset, Michele T. Hu, Jonathan Marchini, Caleb Webber
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background There is large individual variation in both clinical presentation and progression between Parkinson’s disease patients. Generation of deeply and longitudinally phenotyped patient cohorts has enormous potential to identify diseas
Externí odkaz:
https://doaj.org/article/0f75466c5fac46a2b594aaac0a38583f
Autor:
Miriam Vignando, Dominic ffytche, Simon J. G. Lewis, Phil Hyu Lee, Seok Jong Chung, Rimona S. Weil, Michele T. Hu, Clare E. Mackay, Ludovica Griffanti, Delphine Pins, Kathy Dujardin, Renaud Jardri, John-Paul Taylor, Michael Firbank, Grainne McAlonan, Henry K. F. Mak, Shu Leong Ho, Mitul A. Mehta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Visual hallucinations are a prevalent symptom of Parkinson’s disease. Here the authors use a structural mega-analysis to show cortical regions and networks involved in visual hallucinations and associations with receptor density maps.
Externí odkaz:
https://doaj.org/article/fe02463e580e46439d4de51ce0f2d0bd
Autor:
Michael Lawton, Inga Liepelt-Scarfone, Rejko Krüger, Michele T Hu, Christine Lo, Charlotte Woodward, Francesca Bowring, Jessica Welch, Patricia Sulzer, Anne-Marie Hanff
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/12c311c829134c09bb37d22325e86475
Autor:
Diane Stephenson, Robert Alexander, Varun Aggarwal, Reham Badawy, Lisa Bain, Roopal Bhatnagar, Bastiaan R. Bloem, Babak Boroojerdi, Jackson Burton, Jesse M. Cedarbaum, Josh Cosman, David T. Dexter, Marissa Dockendorf, E. Ray Dorsey, Ariel V. Dowling, Luc J. W. Evers, Katherine Fisher, Mark Frasier, Luis Garcia-Gancedo, Jennifer C. Goldsack, Derek Hill, Janice Hitchcock, Michele T. Hu, Michael P. Lawton, Susan J. Lee, Michael Lindemann, Ken Marek, Nitin Mehrotra, Marjan J. Meinders, Michael Minchik, Lauren Oliva, Klaus Romero, George Roussos, Robert Rubens, Sakshi Sadar, Joseph Scheeren, Eiichi Sengoku, Tanya Simuni, Glenn Stebbins, Kirsten I. Taylor, Beatrice Yang, Neta Zach
Publikováno v:
Digital Biomarkers, Vol 4, Iss 1, Pp 28-49 (2020)
Innovative tools are urgently needed to accelerate the evaluation and subsequent approval of novel treatments that may slow, halt, or reverse the relentless progression of Parkinson disease (PD). Therapies that intervene early in the disease continuu
Externí odkaz:
https://doaj.org/article/02833b80db5e4df4916766e3401c1666
Autor:
Thomas R. Barber, Ludovica Griffanti, Kevin M. Bradley, Daniel R. McGowan, Christine Lo, Clare E. Mackay, Michele T. Hu, Johannes C. Klein
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 1, Pp 26-35 (2020)
Abstract Objectives Rapid eye movement sleep behavior disorder (RBD) patients have a high risk of developing a Parkinsonian disorder, offering an opportunity for neuroprotective intervention. Predicting near‐term conversion, however, remains a chal
Externí odkaz:
https://doaj.org/article/e49d2454783f4722939b38ae3e5f78eb
Autor:
Heather D.E. Booth, Frank Wessely, Natalie Connor-Robson, Federica Rinaldi, Jane Vowles, Cathy Browne, Samuel G. Evetts, Michele T. Hu, Sally A. Cowley, Caleb Webber, Richard Wade-Martins
Publikováno v:
Neurobiology of Disease, Vol 129, Iss , Pp 56-66 (2019)
Non-neuronal cell types such as astrocytes can contribute to Parkinson's disease (PD) pathology. The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) is one of the most common known causes of familial PD. To characterize its effect on astrocyt
Externí odkaz:
https://doaj.org/article/2c53914889f24f2e84b456f7cc9c2d65
Autor:
Christine Lo, Siddharth Arora, Fahd Baig, Michael A. Lawton, Claire El Mouden, Thomas R. Barber, Claudio Ruffmann, Johannes C. Klein, Peter Brown, Yoav Ben‐Shlomo, Maarten deVos, Michele T. Hu
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1498-1509 (2019)
Abstract Objective We recently demonstrated that 998 features derived from a simple 7‐minute smartphone test could distinguish between controls, people with Parkinson's and people with idiopathic Rapid Eye Movement sleep behavior disorder, with mea
Externí odkaz:
https://doaj.org/article/46807df211b8446fb949a678609719d6