Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Michele Schuler"'
Autor:
Kevin J Lee, Griffin Wright, Hannah Bryant, Leigh Ann Wiggins, Valeria L. Dal Zotto, Michele Schuler, Christopher Malozzi, Michael V Cohen, Natalie R Gassman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7439 (2021)
Background: Doxorubicin (Dox) is a first-line treatment for triple negative breast cancer (TNBC), but its use may be limited by its cardiotoxicity mediated by the production of reactive oxygen species. We evaluated whether vitamin D may prevent Dox-i
Externí odkaz:
https://doaj.org/article/811c525e37404c55a7176a0cde63f3c3
Autor:
Claire V. Cawthon, Kathryn Cooper, Clifton Huett, Alyssa Lloret, Estefanny Villar-Matamoros, Lauren Stokes, Uwe Christians, Michele Schuler, Saami K. Yazdani
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 434 (2020)
The purpose of this pilot study was to investigate the feasibility of a perfusion catheter to deliver liquid paclitaxel into arterial segments. A clinically relevant rabbit ilio-femoral injury model was utilized to determine the impact of liquid pacl
Externí odkaz:
https://doaj.org/article/af816e45211543229f612fc0b2257a49
Autor:
Buckley, Colin T., Lee, Yannleei L., Michele Schuler, A., Langley, Raymond J., Kutcher, Matthew E., Barrington, Robert, Audia, Jonathon P., Simmons, Jon D.
Publikováno v:
In Injury May 2024 55(5)
Autor:
Christopher Malozzi, Hannah Bryant, Leigh Ann Wiggins, Michele Schuler, Valeria L Dal Zotto, Griffin Wright, Natalie R. Gassman, Kevin Lee, Michael V. Cohen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7439, p 7439 (2021)
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7439, p 7439 (2021)
Volume 22
Issue 14
Background: Doxorubicin (Dox) is a first-line treatment for triple negative breast cancer (TNBC), but its use may be limited by its cardiotoxicity mediated by the production of reactive oxygen species. We evaluated whether vitamin D may prevent Dox-i
Autor:
Andrea G. Kahn, Glenn L. Wilson, Ritu Arora, Lyudmila I. Rachek, Ming Tan, Larysa V. Yuzefovych, Michele Schuler, Lars Eide
Publikováno v:
Cancer research. 81(11)
Production of mitochondrial reactive oxygen species and integrity of mitochondrial DNA (mtDNA) are crucial in breast cancer progression and metastasis. Therefore, we evaluated the role of mtDNA damage in breast cancer by genetically modulating the DN
Autor:
Leigh Ann Wiggins, Hannah Bryant, Griffin Wright, Michele Schuler, Kevin Lee, Natalie R. Gassman
Publikováno v:
Cancer drug resistance (Alhambra, Calif.). 3(4)
Autor:
Clifton Huett, Estefanny Villar-Matamoros, Lauren Stokes, Claire V. Cawthon, Uwe Christians, Kathryn Cooper, Alyssa Lloret, Saami K. Yazdani, Michele Schuler
Publikováno v:
Pharmaceuticals, Vol 13, Iss 434, p 434 (2020)
Pharmaceuticals
Volume 13
Issue 12
Pharmaceuticals
Volume 13
Issue 12
The purpose of this pilot study was to investigate the feasibility of a perfusion catheter to deliver liquid paclitaxel into arterial segments. A clinically relevant rabbit ilio-femoral injury model was utilized to determine the impact of liquid pacl
Autor:
Larysa V. Yuzefovych, Ritu Arora, Michele Schuler, Lars Eide, Ming Tan, Glenn L. Wilson, Lyudmila I. Rachek, Andrea G. Kahn
Publikováno v:
Cancer Research. 76:30-34
Production of mitochondrial reactive oxygen species and integrity of mitochondrial DNA (mtDNA) are crucial in breast cancer progression and metastasis. Therefore, we evaluated the role of mtDNA damage in breast cancer by genetically modulating the DN
Publikováno v:
Cancer Research. 80:3464-3464
Doxorubicin (Dox) is a first-line treatment for triple negative breast cancer (TNBC), which lacks the molecular targets for hormone or growth factor therapy. Although highly effective as a chemotherapeutic agent, Dox induces severe side effects inclu
Autor:
Michele Schuler, Hye Lim Noh, Sujin Suk, Lyudmila I. Rachek, Larysa V. Yuzefovych, Jason K. Kim
Publikováno v:
Diabetes. 67
Mitochondrial DNA (mtDNA) damage has been implicated in the development of insulin resistance. The mtDNA is highly specialized and encodes for proteins essential for energy metabolism. Also, mtDNA damage heightens mitochondrial oxidative stress, whic