Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Michele Rubini"'
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-12 (2023)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder that impairs normal brain development and socio-cognitive abilities. The pathogenesis of this condition points out the involvement of genetic and environmental factors during in
Externí odkaz:
https://doaj.org/article/15261d0bf2874170a99286b453bbc324
Autor:
Silvia Buonaiuto, Immacolata Di Biase, Valentina Aleotti, Amin Ravaei, Adriano De Marino, Gianluca Damaggio, Marco Chierici, Madhuri Pulijala, Palmira D’Ambrosio, Gabriella Esposito, Qasim Ayub, Cesare Furlanello, Pantaleo Greco, Antonio Capalbo, Michele Rubini, Sebastiano Di Biase, Vincenza Colonna
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Miscarriage is the spontaneous termination of a pregnancy before 24 weeks of gestation. We studied the genome of euploid miscarried embryos from mothers in the range of healthy adult individuals to understand genetic susceptibility to miscar
Externí odkaz:
https://doaj.org/article/97530b1c29e640a5ba409b91d6359007
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A long-shared evolutionary history is congruent with the multiple roles played by purinergic signaling in viral infection, replication and host responses that can assist or hinder viral functions. An overview of the involvement of purinergic signalin
Externí odkaz:
https://doaj.org/article/0808011f36e04f6ba0559a70adc921fe
Autor:
Leila Mazdai, Matteo Fabbri, Micaela Tirri, Giorgia Corli, Raffaella Arfè, Beatrice Marchetti, Sabrine Bilel, Eva Bergamin, Rosa Maria Gaudio, Michele Rubini, Fabio De-Giorgio, Matteo Marti
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1398 (2022)
In the recent decade, numerous new psychoactive substances (NPSs) have been added to the illicit drug market. These are synthetized to mimic the effects of classic drugs of abuse (i.e., cannabis, cocaine, etc.), with the purpose of bypassing substanc
Externí odkaz:
https://doaj.org/article/9f5aa959ee4e40a5bfcb83667003f9b7
Autor:
Kerstin U Ludwig, Syeda Tasnim Ahmed, Anne C Böhmer, Nasim Bahram Sangani, Sheryil Varghese, Johanna Klamt, Hannah Schuenke, Pinar Gültepe, Andrea Hofmann, Michele Rubini, Khalid Ahmed Aldhorae, Regine P Steegers-Theunissen, Augusto Rojas-Martinez, Rudolf Reiter, Guntram Borck, Michael Knapp, Mitsushiro Nakatomi, Daniel Graf, Elisabeth Mangold, Heiko Peters
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005914 (2016)
Nonsyndromic orofacial clefts are common birth defects with multifactorial etiology. The most common type is cleft lip, which occurs with or without cleft palate (nsCLP and nsCLO, respectively). Although genetic components play an important role in n
Externí odkaz:
https://doaj.org/article/86fcbe5b9eae4ed2819aa96fe4a4aa5d
Autor:
Francesco Parmeggiani, Francesco S. Sorrentino, Mario R. Romano, Ciro Costagliola, Francesco Semeraro, Carlo Incorvaia, Sergio D'Angelo, Paolo Perri, Katia De Nadai, Elia Bonomo Roversi, Paola Franceschelli, Adolfo Sebastiani, Michele Rubini
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment among people over 50 years of age, accounting for up to 50% of all cases of legal blindness in Western countries. Although the aging represents the main
Externí odkaz:
https://doaj.org/article/3aba3cd3f992420d98de1afc73898483
Autor:
Lijuan Wang, Xue Li, Azita Montazeri, Amanda J. MacFarlane, Franco Momoli, Susan Duthie, Marjanne Senekal, Ines Mesa Eguiagaray, Ron Munger, Derrick Bennett, Harry Campbell, Michele Rubini, Helene McNulty, Julian Little, Evropi Theodoratou
Publikováno v:
Wang, L, Li, X, Montazeri, A, MacFarlane, A J, Momoli, F, Duthie, S J, Senekal, M, Mesa Eguiagaray, I, Munger, R G, Bennett, D, Campbell, H, Rubini, M, McNulty, H, Little, J & Theodoratou, E 2023, ' Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes : analysis of the UK Biobank ', The American Journal of Clinical Nutrition (AJCN), vol. 117, no. 3, pp. 564-575 . https://doi.org/10.1016/j.ajcnut.2023.01.005
Am J Clin Nutr
Am J Clin Nutr
BACKGROUND: Although a number of health outcomes such as cardiovascular diseases, metabolic-related outcomes, neurological disorders, pregnancy outcomes and cancers have been identified in relation to B vitamins, evidence is of uneven quality and vol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092e27e6ee9a555a07597251892ff333
https://www.pure.ed.ac.uk/ws/files/321393440/Phenome_wide_association_study_of_genetically_predicted_B_vitamins_and_homocysteine_biomarkers_with_multiple_health_and_disease_outcomes_analysis_of_the_UK_Biobank.pdf
https://www.pure.ed.ac.uk/ws/files/321393440/Phenome_wide_association_study_of_genetically_predicted_B_vitamins_and_homocysteine_biomarkers_with_multiple_health_and_disease_outcomes_analysis_of_the_UK_Biobank.pdf
Autor:
Amin Ravaei, Lia Pulsatelli, Elisa Assirelli, Riccardo Meliconi, Jacopo Ciaffi, Elisa Gremese, Barbara Tolusso, Carlo Salvarani, Marcello Govoni, Michele Rubini
Publikováno v:
Genes; Volume 13; Issue 11; Pages: 2012
Background: Methotrexate (MTX) is considered the first choice among disease-modifying anti-rheumatic drugs (DMARDs) for rheumatoid arthritis (RA) treatment. However, response to it varies as approximately 40% of the patients do not respond and would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7eeeede5fb8a85e58911cb59788403
Autor:
Amin Ravaei, Michele Rubini
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 115
Rheumatoid Arthritis (RA) is an inflammatory autoimmune disease that affects women three times more than men. Epidemiological studies found that the incidence of Autism Spectrum Disorder (ASD), a neurological and developmental disorder, in children b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8859dd9c5affe58d3dc6615146fa9281
https://pubmed.ncbi.nlm.nih.gov/36402436
https://pubmed.ncbi.nlm.nih.gov/36402436
Publikováno v:
Progress in biophysics and molecular biology. 175
Long noncoding RNAs (lncRNAs) are a regulatory class of noncoding RNAs with a wide range of activities such as transcriptional and post-transcriptional regulations. Emerging evidence has demonstrated that various lncRNAs contribute to the initiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b106cd72929b7271a1c53885cba53b95
https://pubmed.ncbi.nlm.nih.gov/36126801
https://pubmed.ncbi.nlm.nih.gov/36126801