Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michele Raviscioni"'
Autor:
Daniel H. Morgan, Austin J. Cooney, Minawar Sattar, Olivier Lichtarge, Eping Xu, Peili Gu, Ryan T. Wagner, Michele Raviscioni
Publikováno v:
Journal of Biological Chemistry. 280:31818-31829
Germ cell nuclear factor (GCNF) is an orphan nuclear receptor that plays important roles in development and reproduction, by repressing the expression of essential genes such as Oct4, GDF9, and BMP15, through binding to DR0 elements. Surprisingly, wh
Publikováno v:
Journal of Molecular Biology. 350:402-415
Understanding the molecular mechanisms of the specific interaction between transcription factor proteins and DNA is key to comprehend the regulation of gene expression and to develop technologies to engineer transcription factors. Thus far, although
Autor:
Paolo Ciana, Michele Raviscioni, Paola Mussi, Elisabetta Vegeto, Malcolm G Parker, Clemens W.G.M. Löwik, Ivo Que, Adriana Maggi
Publikováno v:
Nature Medicine. 9:82-86
Through intracellular receptors, estrogens control growth, differentiation and function of not only reproductive tissues, but also other systems. Estrogen receptors are ligand-dependent transcription factors whose activity is modulated either by estr
Autor:
Jonathan Lindzey, Michele Raviscioni, Richard P. DiAugustine, Julie F. Foley, Paolo Ciana, Diane M. Klotz, Kenneth S. Korach, Sylvia C. Hewitt, Adriana Maggi
Publikováno v:
Journal of Biological Chemistry. 277:8531-8537
In the uterus insulin-like growth factor-1 (IGF-1) signaling can be initiated by estradiol acting through its nuclear receptor (estrogen receptor (ER)) to stimulate the local synthesis of IGF-1. Conversely, in vitro studies have demonstrated that est
Publikováno v:
Proteins. 64(4)
Nuclear receptors are ubiquitous eukaryotic ligand-activated transcription factors that modulate gene expression through varied interactions. However, the highly conserved functional sites known today seem insufficient to explain receptor specific re
Autor:
Paola Mussi, Adriana Maggi, Michele Raviscioni, E. Agradi, Paolo Ciana, S. Regondi, R. Villa, D. Di Lorenzo
Publikováno v:
Brain research bulletin. 65(3)
The insecticide dichlorodiphenyltrichloroethane (DDT) interferes with physiological endocrine processes modulating estrogens receptor activity. Most of the data describing the DDT mechanism of action have been collected in vitro or in reproductive ti
Autor:
Andrea Biserni, Luisa Ottobrini, Adriana Maggi, Michele Raviscioni, Elisabetta Vegeto, Paola Mussi, Paolo Ciana
Publikováno v:
New Molecular Mechanisms of Estrogen Action and Their Impact on Future Perspectives in Estrogen Therapy ISBN: 9783662053881
Estrogens, by signaling through two nuclear receptors (ERs), ERα and ERβ), can control specific gene networks and modulate target cell activities. In the last decade, cell-based approaches have provided major insights into the transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb934e0304ff06f00451d3f2808b5e3
https://doi.org/10.1007/978-3-662-05386-7_10
https://doi.org/10.1007/978-3-662-05386-7_10
Autor:
Giuseppina Ruggeri, Michele Raviscioni, D. Di Lorenzo, Paolo Ciana, Adriana Maggi, Giorgio Biasiotto, Pietro Apostoli, R. Villa, Silvana Belloli, Alberto Albertini
Publikováno v:
Endocrinology. 143(12)
We investigated the tissue-specific effects of dichlorodyphenyltrichloroethane (DDT) isomers in adult and suckling newborn mice, using a novel mouse line engineered to express a reporter of estrogen receptor transcriptional activity (ERE-tkLUC mouse)