Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Michele R Richards"'
Autor:
Lieke B van Alphen, Cory Q Wenzel, Michele R Richards, Christopher Fodor, Roger A Ashmus, Martin Stahl, Andrey V Karlyshev, Brendan W Wren, Alain Stintzi, William G Miller, Todd L Lowary, Christine M Szymanski
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87051 (2014)
Campylobacter jejuni is a major cause of bacterial gastroenteritis worldwide, and the capsular polysaccharide (CPS) of this organism is required for persistence and disease. C. jejuni produces over 47 different capsular structures, including a unique
Externí odkaz:
https://doaj.org/article/748b570f2d624c9ba8ec4b84dd8038a2
Autor:
Christine M. Szymanski, Harald Nothaft, Rajinder K Dubb, Michele R. Richards, Bernadette Beadle
Publikováno v:
Glycobiology. 30:105-119
Campylobacter jejuni is a prevalent gastrointestinal pathogen associated with increasing rates of antimicrobial resistance development. It was also the first bacterium demonstrated to possess a general N-linked protein glycosylation pathway capable o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8806c83eca2c544e36ce932168d31bb0
https://doi.org/10.1093/glycob/cwz082
https://doi.org/10.1093/glycob/cwz082
Autor:
Gour Chand Daskhan, Michele R. Richards, Christopher W. Cairo, Tianlin Guo, Carmanah D. Hunter
Publikováno v:
Chemical Reviews. 118:8188-8241
The plasma membrane of cells contains a diverse array of lipids that provide important structural and biological features. Glycolipids are typically a minor component of the cell membrane and consist primarily of glycosphingolipids (GSLs). GSLs in ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f075e9c972dd2c72eb9b1d74b587c4c
https://doi.org/10.1021/acs.chemrev.8b00070
https://doi.org/10.1021/acs.chemrev.8b00070
Autor:
Iain D. G. Campuzano, Elena N. Kitova, Gilbert G. Privé, Michele R. Richards, John S. Klassen, Zi Jian Xiong, Dhanashri Bagal, Jun Li
Publikováno v:
Analytical Chemistry. 88:9524-9531
Saposin A (SapA) lipoprotein discs, also known as picodiscs (PDs), represent an attractive method to solubilize glycolipids for protein interaction studies in aqueous solution. Recent electrospray ionization mass spectrometry (ESI-MS) data suggest th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b0535db91ccf22abb0b5ab4adf5d3d
https://doi.org/10.1021/acs.analchem.6b02097
https://doi.org/10.1021/acs.analchem.6b02097
Autor:
Todd L. Lowary, Justin B. Renaud, Michele R. Richards, Elena N. Kitova, Paul M. Mayer, John S. Klassen, Lan Liu, D. Peter Tieleman, Iwona Siuda
Publikováno v:
ChemBioChem. 17:1571-1578
We report a detailed study of the structure and stability of carbohydrate-lipid interactions. Complexes of a methylmannose polysaccharide (MMP) derivative and fatty acids (FAs) served as model systems. The dependence of solution affinities and gas-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3818dee1f47ad4350ed0b48960dda493
https://doi.org/10.1002/cbic.201600123
https://doi.org/10.1002/cbic.201600123
Publikováno v:
Journal of the American Society for Mass Spectrometry. 27:498-506
The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein-ligand affinities are described. Binding measurements carried out on f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a1e85ca12ce30b93dc40c57671c825
https://doi.org/10.1007/s13361-015-1312-x
https://doi.org/10.1007/s13361-015-1312-x
Publikováno v:
Bioorganicmedicinal chemistry. 26(19)
Inhibitors of viral neuraminidase enzymes have been previously developed as therapeutics. Humans can express multiple forms of neuraminidase enzymes (NEU1, NEU2, NEU3, NEU4) that share a similar active site and enzymatic mechanism with their viral co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563099d52979fc7d06b95d57f53e9a83
https://pubmed.ncbi.nlm.nih.gov/29903413
https://pubmed.ncbi.nlm.nih.gov/29903413
Autor:
Peng Ge, Christopher W. Cairo, Philipp Dätwyler, Michele R. Richards, Chunxia Zou, Ekaterina P. Demina, Alexey V. Pshezhetsky, Tianlin Guo, Ruixiang Blake Zheng, Beat Ernst, Anne Fougerat
Publikováno v:
Journal of medicinal chemistry. 61(5)
Human neuraminidases (NEU) are associated with human diseases including cancer, atherosclerosis, and diabetes. To obtain small molecule inhibitors as research tools for the study of their biological functions, we designed a library of 2-deoxy-2,3-did
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84719e6f1a73560f30fe37f473db9d61
https://pubmed.ncbi.nlm.nih.gov/29425031
https://pubmed.ncbi.nlm.nih.gov/29425031
Autor:
Carmanah D. Hunter, Michele R. Richards, Neha Khanna, Reza Rezaei Darestani, John S. Klassen, Christopher W. Cairo, Chunxia Zou
Publikováno v:
ACS chemical biology. 13(4)
Recognition of terminal sialic acids is central to many cellular processes, and structural modification of sialic acid can disrupt these interactions. A prominent, naturally occurring, modification of sialic acid is 9- O-acetylation (9- O-Ac). Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07250f1eac0a3609254f3ca85aaae293
https://pubmed.ncbi.nlm.nih.gov/29341588
https://pubmed.ncbi.nlm.nih.gov/29341588
Autor:
Elena N. Kitova, Xi Jiang, Ling Han, Ming Tan, Michele R. Richards, John S. Klassen, Ruixiang Zheng
Publikováno v:
Glycobiology. 28(7)
Human noroviruses (HuNoVs) are a major cause of acute gastroenteritis. Many HuNoVs recognize histo-blood group antigens (HBGAs) as cellular receptors or attachment factors for infection. It was recently proposed that HuNoV recognition of HBGAs involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb968911e776546c366436b120bfc179
https://pubmed.ncbi.nlm.nih.gov/29562255
https://pubmed.ncbi.nlm.nih.gov/29562255