Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michele Pozzoli"'
Autor:
Adryana Rocha Clementino, Cinzia Marchi, Michele Pozzoli, Franco Bernini, Francesca Zimetti, Fabio Sonvico
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Nasal delivery has been indicated as one of the most interesting alternative routes for the brain delivery of neuroprotective drugs. Nanocarriers have emerged as a promising strategy for the delivery of neurotherapeutics across the nasal epithelia. I
Externí odkaz:
https://doaj.org/article/94bb85708ed14a39892ef522626c656a
Autor:
Arianna Fallacara, Filippo Marchetti, Michele Pozzoli, Ugo Raffaello Citernesi, Stefano Manfredini, Silvia Vertuani
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 254 (2018)
The present work evaluates for the first time the use of urea-crosslinked hyaluronic acid (HA-CL), a novel derivative of native hyaluronic acid (HA), to produce microspheres (MS) by emulsification-solvent evaporation, for dermal delivery of sodium as
Externí odkaz:
https://doaj.org/article/62edb53e56884a4facbb0417050d34f9
Autor:
Gabriela Garrastazu Pereira, Tristan Rawling, Michele Pozzoli, Curtis Pazderka, Yongjuan Chen, Colin R. Dunstan, Michael Murray, Fabio Sonvico
Publikováno v:
Nanomaterials, Vol 8, Iss 10, p 825 (2018)
Lipid-based drugs are emerging as an interesting class of novel anticancer drugs with the potential to target specific cancer cell metabolic pathways linked to their proliferation and invasiveness. In particular, ω-3 polyunsaturated fatty acids (PUF
Externí odkaz:
https://doaj.org/article/d8d95d17ca09435d9abe6060a9aad003
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 156:121-130
Cystic fibrosis (CF) is a disease that most commonly affects the lungs and is characterized by mucus retention and a continuous cycle of bacterial infection and inflammation. Current CF treatment strategies are focused on targeted drug delivery to th
Autor:
Paul M. Young, Tristan A. Reekie, Daniela Traini, Hui Xin Ong, Peta Bradbury, Michael Kassiou, Zara Sheikh, Paul Robinson, Michele Pozzoli
Publikováno v:
European journal of pharmacology. 902
Current cystic fibrosis (CF) treatment strategies are primarily focused on oral/inhaled anti-inflammatories and antibiotics, resulting in a considerable treatment burden for CF patients. Therefore, combination treatments consisting of anti-inflammato
Autor:
Hui Xin Ong, Daniela Traini, Paul M. Young, Laura Busato, Arianna Fallacara, Michele Pozzoli, Maliheh Ghadiri, Stefano Manfredini
Publikováno v:
European Journal of Pharmaceutical Sciences. 120:96-106
This in vitro study evaluated, for the first time, the safety and the biological activity of a novel urea-crosslinked hyaluronic acid component and sodium ascorbyl phosphate (HA-CL - SAP), singularly and/or in combination, intended for the treatment
Publikováno v:
Expert Opinion on Orphan Drugs. 6:69-84
Introduction: Cystic fibrosis (CF) is a congenital life-limiting, orphan disease affecting 1/2500 – 1/3000 people worldwide with the greatest prevalence in Europe, North America and Australia. The ...
Autor:
Elisa Messerotti, Shaokoon Cheng, Hui Xin Ong, Agisilaos Kourmatzis, Hanieh Gholizadeh, Michele Pozzoli, Carla Caramella, Paul M. Young, Daniela Traini
Publikováno v:
AAPS PharmSciTech. 20(7)
The integrity of the nasal epithelium plays a crucial role in the airway defence mechanism. The nasal epithelium may be injured as a result of a large number of factors leading to nose bleeds, also known as epistaxis. However, local measures commonly
Autor:
Paul M. Young, Shaokoon Cheng, Agisilaos Kourmatzis, Elisa Messerotti, Michele Pozzoli, Hui Xin Ong, Daniela Traini, Hanieh Gholizadeh
Publikováno v:
Expert opinion on drug delivery. 16(4)
The in-situ gelation of thermosensitive nasal formulations with desirable spray characteristics at room temperature and ability to undergo a phase change to a semi-solid state with mucoadhesive behavior at physiological temperature has the potential
Autor:
Michele Pozzoli, Wing-Hin Lee, Santo Scalia, Valentina Trotta, Paul M. Young, Daniela Traini, Ching-Yee Loo, Isabella Martignoni
Publikováno v:
Journal of Microencapsulation. 33:735-742
© 2016 Informa UK Limited, trading as Taylor & Francis Group. This study focuses on development and in vitro characterisation of a nasal delivery system based on uncoated or chitosan-coated solid lipid microparticles (SLMs) containing resveratrol, a