Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michele Nutini"'
Autor:
Daniela Francesca Angelini, Federica De Angelis, Valentina Vacca, Eleonora Piras, Chiara Parisi, Michele Nutini, Alida Spalloni, Francesca Pagano, Patrizia Longone, Luca Battistini, Flaminia Pavone, Sara Marinelli
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/a6a6ed83765d45e688c25c58ca120d5f
Autor:
Daniela Francesca Angelini, Federica De Angelis, Valentina Vacca, Eleonora Piras, Chiara Parisi, Michele Nutini, Alida Spalloni, Francesca Pagano, Patrizia Longone, Luca Battistini, Flaminia Pavone, Sara Marinelli
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent preclinical and clinical evidence suggest that immune system has a role in the progression and prognosis of Amyotrophic Lateral Sclerosis (ALS), but the identification of a clear mechanism and immune players remains to be elucidated. Here, we
Externí odkaz:
https://doaj.org/article/394d1a1af048412ab1b5250ff4608787
Autor:
Michela Ferrucci, Alida Spalloni, Alessia Bartalucci, Emanuela Cantafora, Federica Fulceri, Michele Nutini, Patrizia Longone, Antonio Paparelli, Francesco Fornai
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 2, Pp 370-383 (2010)
Transgenic mice expressing the human superoxide dismutase 1 (SOD-1) mutant at position 93 (G93A) develop a phenotype resembling amyotrophic lateral sclerosis (ALS). In fact, G93A mice develop progressive motor deficits which finally lead to motor pal
Externí odkaz:
https://doaj.org/article/fc0a6f47a78348cb820d15c3bf9bb377
Autor:
Stefano Farioli-Vecchioli, Daniele Saraulli, Marco Costanzi, Luca Leonardi, Irene Cinà, Laura Micheli, Michele Nutini, Patrizia Longone, S Paul Oh, Vincenzo Cestari, Felice Tirone
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8339 (2009)
Neurogenesis in the dentate gyrus of the adult hippocampus has been implicated in neural plasticity and memory, but the molecular mechanisms controlling the proliferation and differentiation of newborn neurons and their integration into the synaptic
Externí odkaz:
https://doaj.org/article/a49877fa8e204add946ce5fe8c9c7ded
Publikováno v:
Pathology, Prevention and Therapeutics of Neurodegenerative Disease ISBN: 9789811309434
Since the seminal research that in the early 1990s determined that ALS patients have augmented levels of glutamate in the cerebral spinal fluid bathing the brain and spinal cord, glutamatergic excitotoxicity has been investigated in Amyotrophic Later
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ba996eab836f8b4b4d63355ce3614f
https://doi.org/10.1007/978-981-13-0944-1_6
https://doi.org/10.1007/978-981-13-0944-1_6
Autor:
Patrizia Longone, Alida Spalloni, Stefano L. Sensi, Michele Nutini, Claudia Marini, Valerio Frazzini
Publikováno v:
Neuropharmacology. 60:1200-1208
Zn²+ is co-released at glutamatergic synapses throughout the central nervous system and acts as a neuromodulator for glutamatergic neurotransmission, as a key modulator of NMDA receptor functioning. Zn²+ is also implicated in the neurotoxicity asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47209a05eb4e9b40170e3821014ab987
https://doi.org/10.1016/j.neuropharm.2010.11.001
https://doi.org/10.1016/j.neuropharm.2010.11.001
Autor:
Giorgio Bernardi, Fulvio Florenzano, Michele Nutini, Ruth E. Westenbroek, Patrizia Longone, Alida Spalloni, William A. Catterall, Claudia Marini
Publikováno v:
Molecular and Cellular Neuroscience. 47:108-118
Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the progressive degeneration of motoneurons (MNs). Altered electrical properties have been described in familial and sporadic ALS patients. Cortical and spinal neurons cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2106e070290de3ce8ec5378170c5f0
https://doi.org/10.1016/j.mcn.2011.03.005
https://doi.org/10.1016/j.mcn.2011.03.005
Autor:
Giovanni Davì, Michele Nutini, Angela Falco, Stefania Basili, Maria Teresa Guagnano, Maria Rosaria Manigrasso, Marina Marinopiccoli, Mario R. Romano
Publikováno v:
Journal of Thrombosis and Haemostasis. 1:2330-2334
Summary. Background: Leptin, a hormone secreted by the adipose tissue, might be a link between obesity and increased morbidity for cardiovascular disease. Leptin exerts proinflammatory, pro-angiogenic actions by activating a specific receptor (Ob-Rb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ca5756a355f43b5e38f3d277cf11ca
https://doi.org/10.1046/j.1538-7836.2003.00445.x
https://doi.org/10.1046/j.1538-7836.2003.00445.x
Autor:
Roberta Libner, Joan Clària, Alfonso Catalano, Mario R. Romano, Carlo Crescenzi, Giovanni Davì, Michele Nutini, Antonio Domenico Procopio, Etrusca D'Urbano
Publikováno v:
The FASEB Journal. 15:2326-2336
Evidence indicates that lipoxygenases (LO) may play a role in cancer cell survival. We show that human malignant pleural mesothelial (MM) cells, but not normal mesothelial (NM) cells, express a catalytically active 5-LO. Pharmacological or genetic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96a46e0c0f0d264a6280c270e42760c
https://doi.org/10.1096/fj.01-0150com
https://doi.org/10.1096/fj.01-0150com
Publikováno v:
Proceedings of the National Academy of Sciences. 91:5833-5837
We tested the hypothesis that different genes can have different abilities to be amplified after transfection under comparable selection conditions. DNA from human lymphoid or choriocarcinoma cell lines was transfected into L cells. Transfectants for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef03e69059dae192cf181aa7fcdde777
https://doi.org/10.1073/pnas.91.13.5833
https://doi.org/10.1073/pnas.91.13.5833