Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Michele Migliore"'
Autor:
Federico Tesler, Roberta Maria Lorenzi, Adam Ponzi, Claudia Casellato, Fulvia Palesi, Daniela Gandolfi, Claudia A. M. Gandini Wheeler Kingshott, Jonathan Mapelli, Egidio D'Angelo, Michele Migliore, Alain Destexhe
Publikováno v:
Frontiers in Computational Neuroscience, Vol 18 (2024)
The development of biologically realistic models of brain microcircuits and regions constitutes currently a very relevant topic in computational neuroscience. One of the main challenges of such models is the passage between different scales, going fr
Externí odkaz:
https://doaj.org/article/08ffc0d9398e4549bf5000a8a21c1856
Autor:
Camille Mazzara, Michele Migliore
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Hippocampal Place Cells (PCs) are pyramidal neurons showing spatially localized firing when an animal gets into a specific area within an environment. Because of their obvious and clear relation with specific cognitive functions, Place Cells
Externí odkaz:
https://doaj.org/article/0835a151692d43fa97fd722f343cdece
Autor:
Laila Ananda Blömer, Elisabetta Giacalone, Fatima Abbas, Luiza Filipis, Domenico Tegolo, Michele Migliore, Marco Canepari
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The back-propagation of an action potential (AP) from the axon/soma to the dendrites plays a central role in dendritic integration. This process involves an intricate orchestration of various ion channels, but a comprehensive understanding of the con
Externí odkaz:
https://doaj.org/article/a672d584ea0f4396920981f2b531acdf
Specific patterns of neural activity in the hippocampus after massed or distributed spatial training
Autor:
Eleonora Centofante, Luca Fralleoni, Carmen A. Lupascu, Michele Migliore, Arianna Rinaldi, Andrea Mele
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Training with long inter-session intervals, termed distributed training, has long been known to be superior to training with short intervals, termed massed training. In the present study we compared c-Fos expression after massed and distribu
Externí odkaz:
https://doaj.org/article/d24175ca61b1439d988043a0105b59f3
Autor:
Justinas J. Dainauskas, Paola Vitale, Sebastien Moreno, Hélène Marie, Michele Migliore, Ausra Saudargiene
Publikováno v:
Frontiers in Computational Neuroscience, Vol 17 (2023)
Alzheimer's disease (AD) is a progressive memory loss and cognitive dysfunction brain disorder brought on by the dysfunctional amyloid precursor protein (APP) processing and clearance of APP peptides. Increased APP levels lead to the production of AD
Externí odkaz:
https://doaj.org/article/3fbeb9410990434bb3863503c3256ca1
Autor:
Paola Vitale, Fabio Librizzi, Andrea C. Vaiana, Elisa Capuana, Maurizio Pezzoli, Ying Shi, Armando Romani, Michele Migliore, Rosanna Migliore
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into individual output spikes. These spikes, in turn, act as inputs for other neurons in the network. Neurons must execute this functio
Externí odkaz:
https://doaj.org/article/02ad6e22254048d2aa16beb2b99abb6b
Autor:
Luca Leonardo Bologna, Antonino Tocco, Roberto Smiriglia, Armando Romani, Felix Schürmann, Michele Migliore
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
To build biophysically detailed models of brain cells, circuits, and regions, a data-driven approach is increasingly being adopted. This helps to obtain a simulated activity that reproduces the experimentally recorded neural dynamics as faithfully as
Externí odkaz:
https://doaj.org/article/361d5965719540b2982aa5b2162406ff
Autor:
Aleksandra Topczewska, Elisabetta Giacalone, Wendy S. Pratt, Michele Migliore, Annette C. Dolphin, Mala M. Shah
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112699- (2023)
Summary: Dorsal and ventral medial entorhinal cortex (mEC) regions have distinct neural network firing patterns to differentially support functions such as spatial memory. Accordingly, mEC layer II dorsal stellate neurons are less excitable than vent
Externí odkaz:
https://doaj.org/article/56be061d211b45108b9f50f0c695a6ac
Autor:
Daniela Gandolfi, Jonathan Mapelli, Sergio Solinas, Robin De Schepper, Alice Geminiani, Claudia Casellato, Egidio D’Angelo, Michele Migliore
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract The modeling of extended microcircuits is emerging as an effective tool to simulate the neurophysiological correlates of brain activity and to investigate brain dysfunctions. However, for specific networks, a realistic modeling approach base
Externí odkaz:
https://doaj.org/article/03a7982650ad4fe6be97df24858c00a1
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 3, p e1010942 (2023)
Phase amplitude coupling (PAC) between slow and fast oscillations is found throughout the brain and plays important functional roles. Its neural origin remains unclear. Experimental findings are often puzzling and sometimes contradictory. Most comput
Externí odkaz:
https://doaj.org/article/da86a7c6a1e04a27a0e615f25f2a1604