Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Michele Marcolongo"'
Publikováno v:
ACS Applied Bio Materials. 5:4493-4503
Bone is a complex tissue with robust mechanical and biological properties originating from its nanoscale composite structure. Although much research has been conducted on designing bioinspired artificial bone, the role of biological macromolecules su
Autor:
Beth A. Winkelstein, Evan R. Phillips, Michele Marcolongo, Melissa Franklin, Eric J. Granquist, Megan M. Sperry
Publikováno v:
J Orthop Res
Mechanical stress to the temporomandibular joint (TMJ) is an important factor in cartilage degeneration, with both clinical and preclinical studies suggesting that repeated TMJ overloading could contribute to pain, inflammation, and/or structural dam
Autor:
Michele Marcolongo, Elizabeth Datner, Randy Stevens, Pooja Menon, Scott Eichmann, Bryan Ferrick, Nathan Beatson, John McNamara, Amy L. Throckmorton, Arun Ramakrishnan, Bradley Eshelman, Erik Sundquist, Matthew Hirschhorn, Ellen J. Bass, Nicholas Catucci
Publikováno v:
Annals of Biomedical Engineering
The purpose of this article is to demonstrate how a new cross-community leadership team came together, collaborated, coordinated across academic units with external community partners, and executed a joint mission to address the unmet clinical need f
Publikováno v:
ACS Applied Bio Materials. 4:571-580
Recently, hierarchical polymer nanostructures called nanofiber shish-kebabs (NFSKs) have shown great potential in directing the distribution of minerals for biomineralization. In this work, we repo...
Autor:
Mitsuo Yamauchi, Michele Marcolongo, Kevt’her Hoxha, Becky K. Brisson, X. Sherry Liu, Chao Wang, Qing Li, Masahiko Terajima, Susan W. Volk, Motomi Enomoto-Iwamoto, Abby M. Goldberg, Biao Han, Lin Han
Publikováno v:
Matrix Biol
Despite the fact that type III collagen is the second most abundant collagen type in the body, its contribution to the physiologic maintenance and repair of skeletal tissues remains poorly understood. This study queried the role of type III collagen
Due to its unique and advantageous material properties, polyetheretherketone (PEEK) is an attractive biomaterial for implantable devices. Though concerns exist regarding PEEK for orthopaedic implants due to its bioinertness, the creation of porous ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721deb8ff3c508e725a0aa52d2eea90b
https://doi.org/10.1115/1.0004270v
https://doi.org/10.1115/1.0004270v
Autor:
Michele Marcolongo, Nicholas Bertha, Maria Lefchak, Brandon Shallop, Mary K. Mulcahey, Evan R. Phillips, Katsiaryna Prudnikova, Joseph Sincavage, Brett D. Haislup
Publikováno v:
Journal of Biomedical Materials Research Part A. 107:1977-1987
Biomimetic proteoglycan (BPG) diffusion into articular cartilage has the potential to restore the lost proteoglycan content in osteoarthritic cartilage given these molecules mimic the structure and properties of natural proteoglycans. We examined the
Publikováno v:
Journal of Structural Biology. 206:204-215
Collagen is one of the leading components in extracellular matrix (ECM), providing durability, structural integrity, and functionality for many tissues. Regulation of collagen fibrillogenesis and degradation is important for treating several diseases
Autor:
Katsiaryna Prudnikova, Evan R. Phillips, Diego A. Galindo, Adam J. Taylor, Michele Marcolongo, Mary K. Mulcahey, Richard B. Huneke, J. Steve Hou, Tuan Bui
Publikováno v:
Journal of Orthopaedic Research®. 37:403-411
Biomimetic proteoglycans (BPGs) have the potential to treat osteoarthritis (OA) given that these molecules mimic the structure and properties of natural proteoglycans, which are significantly reduced in OA. We examined the effects of BPGs injected in
Autor:
Mark Petrovic, Mark C. Staub, Tony Yu, Michele Marcolongo, Diego A. Galindo, Aria C. Attia, Christopher Y. Li, Seyong Kim
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterialsREFERENCES. 109(10)
Block copolymers (BCPs) are of growing interest because of their extensive utility in tissue engineering, particularly in biomimetic approaches where multifunctionality is critical. We synthesized polycaprolactone-polyacrylic acid (PCL-b-PAA) BCP and