Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michele M. Temple-Wong"'
Autor:
Aimee R. Raleigh, Michele M. Temple-Wong, David D. Frisbie, Robert L. Sah, C. Wayne McIlwraith
Publikováno v:
American Journal of Veterinary Research. 82:611-618
OBJECTIVE To assess whether the combination of hyaluronan, sodium chondroitin sul-fate, and N-acetyl-d-glucosamine (HCSG) lubricates articular cartilage in vitro and modulates joint lubrication in vivo. ANIMALS 16 healthy adult horses. PROCEDURES The
Autor:
Robert L. Sah, Andrea L. Pallante-Kichura, Albert C. Chen, William D. Bugbee, Michele M. Temple-Wong
Publikováno v:
Journal of Orthopaedic Research. 31:880-886
The long-term efficacy of osteochondral allografts is due to the presence of viable chondrocytes within graft cartilage. Chondrocytes in osteochondral allografts, especially those at the articular surface that normally produce the lubricant proteogly
Autor:
Shuwen Ren, Michele M. Temple-Wong, Albert C. Chen, James A. Koziol, Akihiko Hasegawa, Robert L. Sah, Koichi Masuda, Martin Lotz, Phu Quach, Darryl D. D'Lima, Bradley C. Hansen
Publikováno v:
Arthritis research & therapy, vol 18, iss 1
Arthritis Research & Therapy
Arthritis Research & Therapy
BackgroundOne potential mechanism for early superficial cartilage wear in normal joints is alteration of the lubricant content and quality of synovial fluid. The purpose of this study was to determine if the concentration and quality of the lubricant
Wear-lines and split-lines of human patellar cartilage: relation to tensile biomechanical properties
Autor:
Gayle E. Nugent-Derfus, Megan E. Blewis, Robert L. Sah, Jennifer M. Antonacci, Jennifer Hwang, Van W. Wong, Won C. Bae, Michele M. Temple-Wong
Publikováno v:
Osteoarthritis and Cartilage. 16:841-845
SummaryBackgroundArticular cartilage undergoes age-associated degeneration, resulting in both structural and functional biomechanical changes. At early stages of degeneration, wear-lines develop in the general direction of joint movement. With aging,
Autor:
Alexander Y. Hui, Michele M. Temple-Wong, William D. Bugbee, Paul J. Girard, Jennifer M. Antonacci, Robert L. Sah, Brooke L. Ballard, Barbara L. Schumacher, Alexandra K. Schwartz
Publikováno v:
The Journal of bone and joint surgery. American volume. 94(10)
Traumatic intra-articular fractures, such as those of the tibial plateau, are at risk of joint degeneration and posttraumatic arthritis even when treated according to traditional orthopaedic principles to restore articular congruency and anatomic ali
Autor:
Andrea L, Pallante-Kichura, Albert C, Chen, Michele M, Temple-Wong, William D, Bugbee, Robert L, Sah
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 31(6)
The long-term efficacy of osteochondral allografts is due to the presence of viable chondrocytes within graft cartilage. Chondrocytes in osteochondral allografts, especially those at the articular surface that normally produce the lubricant proteogly
Autor:
Robert L. Sah, Nick Steklov, Won C. Bae, Darryl D. D'Lima, Benjamin J. Fregly, Michele M. Temple-Wong, Lingmin Li, Shantanu Patil
Though changes in normal joint motions and loads (e.g., following anterior cruciate ligament injury) contribute to the development of knee osteoarthritis, the precise mechanism by which these changes induce osteoarthritis remains unknown. As a first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0108ab2ef164b29d90b60b520ff3dfcd
https://europepmc.org/articles/PMC3119794/
https://europepmc.org/articles/PMC3119794/
Autor:
Lingmin Li, Won C. Bae, Shantanu Patil, Benjamin J. Fregly, Robert L. Sah, Michele M. Temple-Wong, Nick Steklov, Darryl D. D'Lima
Publikováno v:
ASME 2010 Summer Bioengineering Conference, Parts A and B.
The mechanism by which altered knee joint motions and loads (e.g., following anterior cruciate ligament (ACL) injury) contribute to the development of knee osteoarthritis (OA) is not well understood. One mechanobiological hypothesis is that articular
Autor:
Gregory M. Williams, Robert L. Sah, William D. Bugbee, Koichi Masuda, Michele M. Temple-Wong, Elaine F. Chan, Won C. Bae
Publikováno v:
Journal of biomechanics. 43(1)
With continued development and improvement of tissue engineering therapies for small articular lesions, increased attention is being focused on the challenge of engineering partial or whole synovial joints. Joint-scale constructs could have applicati
Autor:
H.H. Harith, Michele M. Temple-Wong, Van W. Wong, K.M. Keifer, Martin Lotz, William D. Bugbee, Q.T. Nguyen, Robert L. Sah
Publikováno v:
Osteoarthritis and Cartilage. 16
CTS-induced RAS activation resulted in c-Raf phosphorylation. However, c-Raf activation was not mediated via PAK phosphorylation and was not inhibited by LY294002. These results suggested that RAS activated c-Raf directly without PI-3-kinase mediated