Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michele M. Nava"'
Autor:
Sophie Herzog, Gotthold Fläschner, Ilaria Incaviglia, Javier Casares Arias, Aaron Ponti, Nico Strohmeyer, Michele M. Nava, Daniel J. Müller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The regulation of mass is essential for the development and homeostasis of cells and multicellular organisms. However, cell mass is also tightly linked to cell mechanical properties, which depend on the time scales at which they are measured
Externí odkaz:
https://doaj.org/article/723f03e636b040cca6c4ed2d83c701ef
Autor:
Chen Jiang, Ahsan Javed, Laura Kaiser, Michele M. Nava, Rui Xu, Dominique T. Brandt, Dandan Zhao, Benjamin Mayer, Javier Fernández-Baldovinos, Luping Zhou, Carsten Höß, Kovilen Sawmynaden, Arkadiusz Oleksy, David Matthews, Lee S. Weinstein, Heidi Hahn, Hermann-Josef Gröne, Peter L. Graumann, Carien M. Niessen, Stefan Offermanns, Sara A. Wickström, Thomas Worzfeld
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
It is unclear how epithelial tissues adjust cell division rates to cell density. Here, the authors show that Plexin-B1 and Plexin-B2 sense mechanical compression (crowding) of epidermal stem cells, resulting in inactivation of YAP and suppression of
Externí odkaz:
https://doaj.org/article/c31e77abae1d4cc9839c925693d0c2fb
Autor:
Manuela T. Raimondi, Michele M. Nava, Shane M. Eaton, Arianna Bernasconi, Krishna C. Vishnubhatla, Giulio Cerullo, Roberto Osellame
Publikováno v:
Micromachines, Vol 5, Iss 2, Pp 341-358 (2014)
We applied two-photon polymerization to fabricate 3D synthetic niches arranged in complex patterns to study the effect of mechano-topological parameters on morphology, renewal and differentiation of rat mesenchymal stromal cells. Niches were formed i
Externí odkaz:
https://doaj.org/article/0ec4922ef76a4033b3c3d5876d5a40fa
Autor:
Davide Ricci, Michele M. Nava, Tommaso Zandrini, Giulio Cerullo, Manuela T. Raimondi, Roberto Osellame
Publikováno v:
Materials, Vol 10, Iss 1, p 66 (2017)
Stem-cell-based therapies require a high number (106–109) of cells, therefore in vitro expansion is needed because of the initially low amount of stem cells obtainable from human tissues. Standard protocols for stem cell expansion are currently bas
Externí odkaz:
https://doaj.org/article/9edcf3d65c544a2d9e6949da0dc0a419
Autor:
Sara A. Wickström, Katsuko S. Furukawa, Michele M. Nava, Clémentine Villeneuve, Minki Chang, Takashi Ushida, Koichiro Maki
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
J Cell Sci
article-version (VoR) Version of Record
J Cell Sci
Articular cartilage protects and lubricates joints for smooth motion and transmission of loads. Owing to its high water content, chondrocytes within the cartilage are exposed to high levels of hydrostatic pressure, which has been shown to promote cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d71434c858c80cab25653acf715b8
http://europepmc.org/articles/PMC7860130
http://europepmc.org/articles/PMC7860130
Autor:
Hermann-Josef Groene, Dominique T. Brandt, Stefan Offermanns, Chen Jiang, Lee S. Weinstein, Arkadiusz Oleksy, David A. Matthews, Javier Fernandez-Baldovinos, Carsten Hoess, Carien M. Niessen, Laura Kaiser, Sara A. Wickström, Ahsan Javed, Thomas Worzfeld, Kovilen Sawmynaden, Luping Zhou, Dandan Zhao, Michele M. Nava
The precise spatiotemporal control of cell proliferation is key to the morphogenesis of epithelial tissues. Epithelial cell divisions lead to tissue crowding and local changes in force distribution, which in turn suppress the rate of cell divisions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980562200bf0b0fd3f38d22aad2a3634
https://doi.org/10.1101/2020.04.30.070359
https://doi.org/10.1101/2020.04.30.070359
Autor:
Giuseppe M. Peretti, Cinzia Domeneghini, Chiara Scandone, Matteo Laganà, Alessandro Sannino, D. Deponti, Federica Boschetti, Manuela Teresa Raimondi, Claudio Conci, Alessia Di Giancamillo, Michele M. Nava, Michele Crestani, Francesca Gervaso
Publikováno v:
The International Journal of Artificial Organs. 41:400-412
Introduction: An innovative approach to the treatment of tendon injury or degeneration is given by engineered grafts, made available through the development of bioreactors that generate tendon tissue in vitro, by replicating in vivo conditions. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50a3a45c440fd422daf08111dbed5a4
https://doi.org/10.1177/0391398818774496
https://doi.org/10.1177/0391398818774496
Autor:
Hadis Eghbali, Manuela Teresa Raimondi, Davod Mohebbi-Kalhori, Gabriella Leonardi, Michele M. Nava, Roberto Sebastiano, Abdolreza Samimi
Publikováno v:
The International Journal of Artificial Organs
Introduction Perfused bioreactors have been demonstrated to be effective in the delivery of nutrients and in the removal of waste products to and from the interior of cell-populated three-dimensional scaffolds. In this paper, a perfused bioreactor ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0f2c21a9db835c21a7ba69592bea2e
https://doi.org/10.5301/ijao.5000554
https://doi.org/10.5301/ijao.5000554
Publikováno v:
Journal of Applied Biomaterials & Functional Materials. 14:e223-e229
Introduction The effect of scaffold pore size and interconnectivity is undoubtedly a crucial factor for most tissue engineering applications. The aim of this study was to examine the effect of pore size and porosity on cartilage construct development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22e47c67af9cafbee8ef620b62a423d
https://doi.org/10.5301/jabfm.5000302
https://doi.org/10.5301/jabfm.5000302
Autor:
Tommaso Zandrini, Roberto Osellame, Giulio Cerullo, Ivan Martin, Michele M. Nava, Manuela Teresa Raimondi, Nunzia Di Maggio
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:2836-2845
The present study reports on the development of an innovative culture substrate, micro-fabricated by two-photon laser polymerization (2PP) in a hybrid organic–inorganic photoresin. It was previously demonstrated that this substrate is able to guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b718334f96f27a6faa035e7fe5cedc17
https://doi.org/10.1002/term.2187
https://doi.org/10.1002/term.2187