Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michele M. Cudahy"'
Autor:
Mary L. Knechtel, Michael W. Wathen, Fred L. Homa, Janet L. Wieber, Michele M. Cudahy, Thomas W. Pitts, Roger A. Poorman, Nancee L. Oien, Mark E. Schnute, Todd A. Hopkins, Roger J. Brideau
Publikováno v:
Journal of Medicinal Chemistry. 48:5794-5804
A novel series of 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potential antivirals against human herpesvirus infections resulting from human cytomegalovirus (HCMV), herpes simplex virus type 1 (HSV-1), and varicella-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45b73ecc9d7de70e829ac53f7d84990
https://doi.org/10.1021/jm050162b
https://doi.org/10.1021/jm050162b
Autor:
Michele M. Cudahy, Edward W. Thomas
Publikováno v:
The Journal of Organic Chemistry. 58:1623-1627
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238e2db00dabc2e8efe73c6b161d99c5
https://doi.org/10.1021/jo00058a061
https://doi.org/10.1021/jo00058a061
Autor:
Mari L. Stephan, Michele M. Cudahy, Janet L. Wieber, Allen Scott, Sarah A. Collier, Robert S. Sackett, Mark E. Schnute, Roger J. Brideau, Todd A. Hopkins, Michael W. Wathen, Nancee L. Oien, Mary L. Knechtel
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(14)
A versatile synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxylate esters has been developed which has lead to the identification of a new series of non-nucleoside inhibitors of human herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e376eb4f4e4856fd6930c7111eb0f1
https://pubmed.ncbi.nlm.nih.gov/18595689
https://pubmed.ncbi.nlm.nih.gov/18595689
Autor:
Roger J. Brideau, David J. Anderson, Steven P. Tanis, Michael J. Genin, Euibong J. Kim, Nancee L. Oien, James A. Nieman, Mark E. Schnute, Valerie A. Vaillancourt, Allen Scott, Thomas M. Judge, Fred L. Ciske, Mary L. Knechtel, Sajiv Krishnan Nair, Marijean Eggen, Michele M. Cudahy, Sarah A. Collier, Janet L. Wieber, Michael W. Wathen, Todd A. Hopkins
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(12)
A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c003e07737e19e2a8033c8a023d0a5f
https://pubmed.ncbi.nlm.nih.gov/17434304
https://pubmed.ncbi.nlm.nih.gov/17434304
Autor:
J E Burr, Scott D. Larsen, Paul D. May, Steven P. Tanis, F C Stevens, Michele M. Cudahy, J H Yu, John A. Tucker, M D Meglasson, V A Vaillancourt, Thomas J. Vidmar, M A Connell, D D Robinson, P V Fisher, B R Evans
Publikováno v:
Journal of medicinal chemistry. 44(8)
3-Guanidinopropionic acid (1) has been demonstrated both to improve insulin sensitivity and to promote weight loss selectively from adipose tissue in animal models of non-insulin-dependent diabetes mellitus (NIDDM). However, 1 has also been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc99ed8c7655ca2625a9c74ec2d0c03
https://pubmed.ncbi.nlm.nih.gov/11312923
https://pubmed.ncbi.nlm.nih.gov/11312923
Autor:
W. Watt, Theresa J. O’Sullivan, Steven P. Tanis, J C Sih, J H Yu, Valerie A. Vaillancourt, M A Connell, Heinrich J. Schostarez, John A. Tucker, Thomas J. Vidmar, M D Meglasson, Michele M. Cudahy, C M Tegley, Scott D. Larsen, F C Stevens, Paul D. May, B R Evans
Publikováno v:
Journal of medicinal chemistry. 44(8)
3-Guanidinopropionic acid (1, PNU-10483) has been demonstrated to both improve insulin sensitivity and to promote weight loss selectively from adipose tissue in animal models of non-insulin-dependent diabetes mellitus (NIDDM). However, 1 has also bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a34af10b390522d35c0dea310dcc92
https://pubmed.ncbi.nlm.nih.gov/11312922
https://pubmed.ncbi.nlm.nih.gov/11312922