Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michele M Kosiewicz"'
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/0993825a5bb7447e918d126374a20fa1
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Our immune system has evolved to recognize and eradicate pathogenic microbes. However, we have a symbiotic relationship with multiple species of bacteria that occupy the gut and comprise the natural commensal flora or microbiota. The microbiota is cr
Externí odkaz:
https://doaj.org/article/d927126ba25545a8a5437122d8a3626a
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3739 (2008)
BACKGROUND: Defects in APC and regulatory cells are associated with diabetes development in NOD mice. We have shown previously that NOD APC are not effective at stimulating CD4(+)CD25(+) regulatory cell function in vitro. We hypothesize that failure
Externí odkaz:
https://doaj.org/article/ed2fd53f6af84befb4be0229b3da1966
Autor:
Evan P. Williams, Aadrita Nandi, Victoria Nam, Linda J. S. Allen, A. Alexandre Trindade, Michele M. Kosiewicz, Colleen B. Jonsson
Publikováno v:
Viruses, Vol 15, Iss 9, p 1806 (2023)
Hantaviruses, genus Orthohantavirus, family Hantaviridae, order Bunyavirales, are negative-sense, single-stranded, tri-segmented RNA viruses that persistently infect rodents, shrews, and moles. Of these, only certain virus species harbored by rodents
Externí odkaz:
https://doaj.org/article/e516786b00634e1989470c412b42e2f0
Publikováno v:
Autoimmunity, Vol 53, Iss 6, Pp 323-332 (2020)
Although the relationship between autoimmunity and microorganisms is complex, there is evidence that microorganisms can prevent the development of various autoimmune diseases. Lactobacilli are beneficial gut bacteria that play an important role in im
Externí odkaz:
https://doaj.org/article/8be6ea4948814559a97e33211c2da488
Autor:
James W Harder, Jing Ma, Pascale Alard, Kevin J Sokoloski, Edith Mathiowitz, Stacia Furtado, Nejat K Egilmez, Michele M Kosiewicz
Publikováno v:
Journal of Leukocyte Biology. 113:41-57
Systemic lupus erythematosus development is influenced by both sex and the gut microbiota. Metabolite production is a major mechanism by which the gut microbiota influences the immune system, and we have previously found differences in the fecal meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5102cfbc1696245e7a2e9ae7c564685
https://doi.org/10.1093/jleuko/qiac002
https://doi.org/10.1093/jleuko/qiac002
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17c0c6b63f7f7efa38919d3bf67d046
https://doi.org/10.1136/lupus-2021-lupus21century.82
https://doi.org/10.1136/lupus-2021-lupus21century.82
Publikováno v:
The Journal of Immunology. 208:158.11-158.11
Hormones and gut microbiota affect lupus. In female NZBxNZW1(BWF1) mice, androgen treatment abrogates lupus; castration/treatment with androgen receptor blocker (flutamide) induces disease in BWF1 male mice. Gut microbiota alterations have been repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c9f30883ac54a3c6b997b58c3f7673
https://doi.org/10.4049/jimmunol.208.supp.158.11
https://doi.org/10.4049/jimmunol.208.supp.158.11
Publikováno v:
Autoimmunity. 53(6)
Although the relationship between autoimmunity and microorganisms is complex, there is evidence that microorganisms can prevent the development of various autoimmune diseases. Lactobacilli are beneficial gut bacteria that play an important role in im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61909c59333defd7cdbd1e3880a0bda7
https://pubmed.ncbi.nlm.nih.gov/32552071
https://pubmed.ncbi.nlm.nih.gov/32552071
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
Dendritic cells (DCs) from NOD mice produced high levels of IL-12 that induce IFNγ-producing T cells involved in diabetes development. We propose to utilize the microorganism ability to induce tolerogenic DCs to abrogate the proinflammatory process
Externí odkaz:
https://doaj.org/article/2b00b80485ad44f5930b0c2fbab45849