Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michele M, Skopec"'
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 95
The vast diversity of cytochrome P450 enzymes in mammals has been proposed to result in large measure from plant-animal warfare, whereby evolution of chemical defenses such as phenolics and terpenoids in plants led to duplication and divergence of P4
Publikováno v:
The Journal of Wildlife Management. 84:1306-1314
Autor:
M. Denise Dearing, P. Ross Wilderman, Michele M. Skopec, James R. Halpert, Katharina Schramm, Teri J. Orr, Smiljka Kitanovic
Publikováno v:
Molecular Ecology. 29:1674-1683
Although herbivory is widespread among mammals, few species have adopted a strategy of dietary specialization. Feeding on a single plant species often exposes herbivores to high doses of plant secondary metabolites (PSMs), which may exceed the animal
Publikováno v:
Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary ISBN: 9780323911092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81afa3ebfc9b83f13fa1402225de4800
https://doi.org/10.1016/bs.apha.2022.05.002
https://doi.org/10.1016/bs.apha.2022.05.002
Publikováno v:
Journal of Chemical Ecology. 45:993-1003
Terpenes, volatile plant secondary compounds produced by woody plants, have historically been thought to act as feeding deterrents for mammalian herbivores. However, three species of woodrats, Neotoma stephensi, N. lepida, and N. albigula, regularly
Autor:
Tyson Sandoval, Clint Wirick, Sheila Murray, Valerie C. Pence, Jennifer Lewinsohn, Linda Whitham, Michele M. Skopec
Publikováno v:
Restoration Ecology. 26:629-635
Autor:
Masako N. Wright, Samuel I. Zeveloff, Barbara A. Wachocki, Michele M. Skopec, Jennifer M. Schmalz
Publikováno v:
Western North American Naturalist. 74:456-466
The pygmy rabbit (Brachylagus idahoensis), the world's smallest rabbit, has a limited distribution due to its year round dependence on sagebrush (Artemisia tridentata) for food and shelter. Due to accelerating habitat loss from fragmentation, develop
Publikováno v:
Physiological and Biochemical Zoology. 86:593-601
An in vivo assay using the cytochrome P450 (P450) suicide inhibitor 1-aminobenzotriazole (ABT) and 24 hour food intake was developed to determine the relative importance of P450s in two populations of Neotoma lepida with respect to biotransformation
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 157:72-79
When herbivores come in contact with volatile plant secondary compounds (PSC) that enter the nasal passages the only barrier between the nasal cavity and the brain is the nasal epithelium and the biotransformation enzymes present there. The expressio
Autor:
Michele M. Skopec, M. Denise Dearing
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 154:383-390
Mammalian herbivores, particularly dietary specialists must have an efficient means to metabolize the high doses of plant secondary compounds they consume. We found previously that Neotoma stephensi, a juniper specialist, upregulated catechol-O-methy