Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study.

Autor: Jeffrey J Szymanski, R Taylor Sundby, Paul A Jones, Divya Srihari, Noah Earland, Peter K Harris, Wenjia Feng, Faridi Qaium, Haiyan Lei, David Roberts, Michele Landeau, Jamie Bell, Yi Huang, Leah Hoffman, Melissa Spencer, Matthew B Spraker, Li Ding, Brigitte C Widemann, Jack F Shern, Angela C Hirbe, Aadel A Chaudhuri

Publikováno v: PLoS Medicine, Vol 18, Iss 8, p e1003734 (2021)

BackgroundThe leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of N

Externí odkaz: https://doaj.org/article/c4e51b3f384e4d0d940d39076a2a352f

Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study

Autor: Wenjia Feng, Jack F. Shern, R. Taylor Sundby, Divya Srihari, Noah Earland, Yi Huang, Paul Jones, David D. Roberts, Melissa Spencer, Faridi Qaium, Brigitte C. Widemann, Leah Hoffman, Jamie Bell, Peter K. Harris, Li Ding, Aadel A. Chaudhuri, Jeffrey J. Szymanski, Matthew B. Spraker, Michele Landeau, Haiyan Lei, Angela C. Hirbe

Publikováno v: PLoS Medicine
PLoS medicine, 18(8):e1003734
PLoS Medicine, Vol 18, Iss 8, p e1003734 (2021)

Background The leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e23e4617fd9614615fab2f5926f8b6
https://doi.org/10.1371/journal.pmed.1003734

Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations

Autor: Iris Lee, Indira U. Mysorekar, Michele Landeau, George A. Macones, Carolyn Bower, Bridget Conlon, Kimberly A. Roehl, Qiuhong Zhao, Molly J. Stout, D. Michael Nelson

Objective Bacteria have been identified in different regions of the placenta. Here, we tested the hypothesis that the maternal basal plate of the placenta harbors microbes that may be associated with adverse pregnancy outcomes. Study Design We perfor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6649f584f5746853a1a94c94e16e7933
https://europepmc.org/articles/PMC3740162/

Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study.

Autor: Szymanski, Jeffrey J.¹ (AUTHOR), Sundby, R. Taylor² (AUTHOR), Jones, Paul A.^1,3 (AUTHOR), Srihari, Divya⁴ (AUTHOR), Earland, Noah^1,3 (AUTHOR), Harris, Peter K.¹ (AUTHOR), Feng, Wenjia¹ (AUTHOR), Qaium, Faridi¹ (AUTHOR), Lei, Haiyan² (AUTHOR), Roberts, David⁴ (AUTHOR), Landeau, Michele⁴ (AUTHOR), Bell, Jamie⁴ (AUTHOR), Huang, Yi¹ (AUTHOR), Hoffman, Leah² (AUTHOR), Spencer, Melissa² (AUTHOR), Spraker, Matthew B.^1,5 (AUTHOR), Ding, Li^4,5,6,7 (AUTHOR), Widemann, Brigitte C.² (AUTHOR), Shern, Jack F.² (AUTHOR) john.shern@nih.gov, Hirbe, Angela C.^3,4,5,8 (AUTHOR) john.shern@nih.gov

Publikováno v: PLoS Medicine. 8/31/2021, Vol. 18 Issue 8, p1-23. 23p. 1 Diagram, 7 Graphs.

Increased human leukocyte antigen-G expression at the maternal-fetal interface is associated with preterm birth.

Autor: Stout, Molly J., Cao, Bin, Landeau, Michele, French, Jacob, Macones, George A., Mysorekar, Indira U.

Publikováno v: Journal of Maternal-Fetal & Neonatal Medicine; Mar2015, Vol. 28 Issue 4, p454-459, 6p