Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michele L. Parry"'
Autor:
Nicolette M. Clark, Carlos A. Garcia Galindo, Vandan K. Patel, Michele L. Parry, Rebecca J. Stoll, John M. Yavorski, Elizabeth P. Pinkason, Edna M. Johnson, Chelsea M. Walker, Joseph Johnson, Wade J. Sexton, Domenico Coppola, George Blanck
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that
Externí odkaz:
https://doaj.org/article/31bde621267a46e3812b11b3a79e3623
Autor:
Elizabeth P. Pinkason, Vandan K. Patel, Joseph O. Johnson, Edna M. Johnson, Chelsea Walker, John M. Yavorski, Michele L. Parry, Wade J. Sexton, Rebecca J. Stoll, Domenico Coppola, Nicolette M. Clark, Carlos A. Garcia Galindo, George Blanck
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 17, Iss 1, Pp 1-9 (2017)
Cancer Cell International, Vol 17, Iss 1, Pp 1-9 (2017)
Background Forty years ago the actin cytoskeleton was determined to be disrupted in fibroblasts from persons with DNA repair-defective, hereditary colon cancer, with no clear connection between the cytoskeleton and DNA repair defects at that time. Re
Publikováno v:
Cancer Letters. 356:479-482
We determined the most commonly mutated genes in five cancer genome atlas (TCGA) datasets. Many of these genes were extraordinarily large, as are many cancer fusion gene partners. And many of these genes had cytoskeletal related functions. We further
Publikováno v:
Cancer genomicsproteomics. 12(6)
Oncoprotein genes are over-represented in statically defined, low mutation-frequency fractions of cancer genome atlas (TCGA) datasets, consistent with a higher driver mutation density.We developed a "continuously variable fraction" (CVF) approach to