Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michele L Archibald"'
Autor:
Balwantray C Chauhan, Kelly T Stevens, Julie M Levesque, Andrea C Nuschke, Glen P Sharpe, Neil O'Leary, Michele L Archibald, Xu Wang
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40352 (2012)
Retinal ganglion cells (RGCs) die in sight-threatening eye diseases. Imaging RGCs in humans is not currently possible and proof of principle in experimental models is fundamental for future development. Our objective was to quantify RGC density and r
Externí odkaz:
https://doaj.org/article/a761a4de37c94de591cdf4e3a997b469
Publikováno v:
British Journal of Ophthalmology. 94:1233-1238
Aim To characterise the influence of endothelin-1 (ET-1), a vasoactive peptide, and its receptors (endothelin B (ETB) and endothelin A (ETA)) on rat optic nerve head astrocyte (ONHA) proliferation. Methods ONHAs were isolated from adult Brown Norway
Publikováno v:
Neuroscience Letters. 468:110-114
We investigated the specificity of cyan fluorescent protein (CFP) expression in retinal ganglion cells (RGCs) of the transgenic Thy1-CFP (B6.Cg-Tg(Thy1-CFP)23Jrs/J) mouse line, and the characteristics of these cells after optic nerve injury. RGCs of
Publikováno v:
Clinical & Experimental Ophthalmology. 37:299-307
We wanted to investigate whether heat shock protein (HSP) 27 and HSP 72 are induced in retinal ganglion cells (RGCs) after acute intraocular pressure (IOP)-induced ischaemia.Retinal ischaemia was induced by acutely increasing IOP to 100-110 mmHg for
Publikováno v:
Experimental Eye Research. 88:378-385
The purpose of this study was to determine whether endothelin B (ETB) receptor levels in the optic nerve are related to retinal ganglion cell (RGC) loss in a model of chronic endothelin-1 (ET-1) induced optic neuropathy. RGCs of adult Brown Norway ra
Publikováno v:
Brain Research. 1063:114-120
A subpopulation of neurons in the inner nuclear layer (INL) of the rat retina were labeled 9-13 weeks after application of Fluorogold (FG) to the superior colliculus. Neurobiotin injection of FG-labeled cells in the INL of flatmounted living retina r
Autor:
Balwantray C. Chauhan, Michele L. Archibald, George S. Robertson, Terry L. LeVatte, Darryl C. Baptiste, Melanie E. M. Kelly, K.J. Powell, C.M. Hamilton, Christine A. B. Jollimore
Publikováno v:
Neuroscience. 134:575-582
In the present study, we compared the in vivo neuroprotective efficacy of intraperitoneally administered tetracycline and minocycline to enhance the survival of retinal ganglion cells (RGCs) following unilateral axotomy of the adult rat optic nerve.
Autor:
Michele L. Archibald, Melanie E. M. Kelly, Alexander Y Tan, François Tremblay, Balwantray C. Chauhan, Terry L. LeVatte
Publikováno v:
Journal of Glaucoma. 11:134-142
Purpose Topical beta-blockers, such as timolol, have been used extensively in the medical treatment of glaucoma to lower intraocular pressure (IOP). Recently, these drugs have been shown to have effects on the retinal and optic nerve circulation as w
Autor:
Xu Wang, Balwantray C. Chauhan, Neil O'Leary, Michele L. Archibald, Glen P. Sharpe, Kelly Stevens, Andrea C. Nuschke, Julie M. Levesque
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40352 (2012)
PLoS ONE
PLoS ONE
Background: Retinal ganglion cells (RGCs) die in sight-threatening eye diseases. Imaging RGCs in humans is not currently possible and proof of principle in experimental models is fundamental for future development. Our objective was to quantify RGC d
Publikováno v:
Investigative ophthalmologyvisual science. 52(10)
To characterize the influence of endothelin-1 (ET-1) on optic nerve head astrocyte (ONHA) proliferation and Ca²⁺ signaling in ONHAs lacking functional endothelin B (ETB) receptors.ONHAs were isolated from adult wild type (WT) and transgenic spotti