Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C

Autor: Aline B. Maddux, Cameron C. Young, Suden Kucukak, Laura D. Zambrano, Margaret M. Newhams, Caitlin K. Rollins, Natasha B. Halasa, Shira J. Gertz, Elizabeth H. Mack, Stephanie Schwartz, Michele Kong, Laura L. Loftis, Katherine Irby, Courtney M. Rowan, Keiko M. Tarquinio, Matt S. Zinter, Hillary Crandall, Natalie Z. Cvijanovich, Jennifer E. Schuster, Julie C. Fitzgerald, Mary A. Staat, Charlotte V. Hobbs, Ryan A. Nofziger, Steven Shein, Heidi Flori, Melissa L. Cullimore, Brandon M. Chatani, Emily R. Levy, Katri V. Typpo, Janet R. Hume, Angela P. Campbell, Adrienne G. Randolph, the Overcoming COVID-19 Investigators, Meghan Murdock, Heather Kelley, Candice Colston, Mary Glas Gaspers, Ronald C. Sanders, Emily Port, Rachel Mansour, Sara Shankman, Kaitlin Jones, Caitlin Rollins, Tanya Novak, Janet Chou, Mary Beth Son, Julia Clarke, Brooke Sens, Eve Listerud, Sabrina Chen, Kasey Stewart, Heidi R. Flori, Mary K. Dahmer, Supriya Behl, Noelle M. Drapeau, Lora Martin, Lacy Malloch, Maygan Martin, Kayla Patterson, Cameron Sanders, Kengo Inagaki, Sarah McGraw, Anita Dhanrajani, Abigail Kietzman, Shannon Hill, Russell J. McCulloh, Stephanie P. Schwartz, Tracie C. Walker, Mary Allen Staat, Rajashri Rasal, Ryan Burnett, Jenny Bush, Meena Golcha, Laura Stewart, Krow Ampofo, Manish M. Patel, Leora R. Feldstein, Mark W. Tenforde, Ashley M. Jackson, Angela Campbell

Publikováno v: Frontiers in Pediatrics, Vol 11 (2023)

ObjectiveTo identify risk factors for persistent impairments after pediatric hospitalization for acute coronavirus disease 2019 (COVID-19) or multisystem inflammatory syndrome in children (MIS-C) during the SARS-CoV-2 pandemic.MethodsAcross 25 U.S. O

Externí odkaz: https://doaj.org/article/1e2f7cbc16d047dbab50b8aeff084f5e

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C

Autor: Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as chi

Externí odkaz: https://doaj.org/article/e95d32cb646c4ee9abe90f1a0721b0aa

On Heidis, Howards, and Hierarchies: Gender Gap in Medicine

Autor: Michele Kong

Publikováno v: Frontiers in Pediatrics, Vol 10 (2022)

Externí odkaz: https://doaj.org/article/db239647ed6a4936a94af83840e4cc7c

Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents

Autor: Alon Geva, Manish M. Patel, Margaret M. Newhams, Cameron C. Young, Mary Beth F. Son, Michele Kong, Aline B. Maddux, Mark W. Hall, Becky J. Riggs, Aalok R. Singh, John S. Giuliano, Charlotte V. Hobbs, Laura L. Loftis, Gwenn E. McLaughlin, Stephanie P. Schwartz, Jennifer E. Schuster, Christopher J. Babbitt, Natasha B. Halasa, Shira J. Gertz, Sule Doymaz, Janet R. Hume, Tamara T. Bradford, Katherine Irby, Christopher L. Carroll, John K. McGuire, Keiko M. Tarquinio, Courtney M. Rowan, Elizabeth H. Mack, Natalie Z. Cvijanovich, Julie C. Fitzgerald, Philip C. Spinella, Mary A. Staat, Katharine N. Clouser, Vijaya L. Soma, Heda Dapul, Mia Maamari, Cindy Bowens, Kevin M. Havlin, Peter M. Mourani, Sabrina M. Heidemann, Steven M. Horwitz, Leora R. Feldstein, Mark W. Tenforde, Jane W. Newburger, Kenneth D. Mandl, Adrienne G. Randolph

Publikováno v: EClinicalMedicine, Vol 40, Iss , Pp 101112- (2021)

Background: Multisystem inflammatory syndrome in children (MIS-C) consensus criteria were designed for maximal sensitivity and therefore capture patients with acute COVID-19 pneumonia. Methods: We performed unsupervised clustering on data from 1,526

Externí odkaz: https://doaj.org/article/0da407d35ec1438f995441c601ff9850

Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza

Autor: Michaël S. Sauthier, MD MBI, Philippe A. Jouvet, MD, PhDMBA, Margaret M. Newhams,, MPH, Adrienne G. Randolph, MD, MSc, for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Pediatric Intensive Care Influenza (PICFLU) Network Investigators, Michele Kong, Ronald C. Sanders, Jr, Olivia K. Irby, David Tellez, Katri Typpo, Barry Markovitz, Natalie Cvijanovich, Heidi Flori, Adam Schwarz, Nick Anas, Patrick McQuillen, Peter Mourani, John S. Giuliano, Jr., Gwenn McLaughlin, Matthew Paden, Keiko Tarquinio, Bria M. Coates, Neethi Pinto, Juliane Bubeck Wardenburg, Janice Sullivan, Vicki Montgomery, Adrienne G. Randolph, Anna A. Agan, Tanya Novak, Margaret M. Newhams, Melania Bembea, Sapna R. Kudchadkar, Stephen C. Kurachek, Mary E. Hartman, Edward J. Truemper, Sidharth Mahapatra, Sholeen Nett, Daniel L. Levin, Kate G. Ackerman, Ryan Nofziger, Steven L. Shein, Mark W. Hall, Neal Thomas, Scott L. Weiss, Julie Fitzgerald, Renee Higgerson, Laura L. Loftis, Rainer G. Gedeit

Publikováno v: Critical Care Explorations, Vol 2, Iss 8, p e0175 (2020)

Background:. Influenza virus is a major cause of acute hypoxemic respiratory failure. Early identification of patients who will suffer severe complications can help stratify patients for clinical trials and plan for resource use in case of pandemic.

Externí odkaz: https://doaj.org/article/ca6d7df3e8c14e91a9b1f188a01d97ae