Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michele Hinerasky da Silva"'
Autor:
Hellen Marianne de Oliveira Costa, Wagner Seixas da-Silva, Michele Hinerasky da Silva, Camila Lüdke Rossetti, Denise P. Carvalho, Clarissa Souza Barthem
Publikováno v:
Experimental Physiology. 104:677-690
NEW FINDINGS What is the central question of this study? Is there sexual dimorphism in the occurrence of hepatic endoplasmic reticulum stress? What is the main finding and its importance? The transition from prepubertal to the adult age is associated
Autor:
Wagner Seixas da-Silva, Aline Machado de Oliveira, Michele Hinerasky da Silva, Flavia Letícia Martins Peçanha
Publikováno v:
Life Sciences. 179:98-102
Hexokinase (HK) is the first enzyme in the glycolytic pathway and is responsible for glucose phosphorylation and fixation into the cell. HK (HK-II) is expressed in skeletal muscle and can be found in the cytosol or bound mitochondria, where it can pr
Autor:
Guilherme Pires Amaral, Nelson Rodrigues de Carvalho, Michele Hinerasky da Silva, Glaecir Roseni Mundstock Dias, Félix Alexandre Antunes Soares, Thiago Henrique Lugokenski, Roselei Fachinetto, Rômulo Pillon Barcelos, Fernando Dobrachinski, Rafael de Lima Portella
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 98
The high levels of oxidative stress and inflammation can be present in the etiology of degenerative intestinal pathologies associated with ethanol ingestion. The Rosmarinus officinalis L. has exhibited several physiological and medicinal activities.
Autor:
João Rocha, Fernando Dobrachinski, Élgion Lúcio da Silva Loreto, Cintia C. Tassi, Nelson Rodrigues de Carvalho, Michele Rechia Fighera, Ronaldo Medeiros Golombieski, Glaecir Roseni Mundstock Dias, Félix Alexandre Antunes Soares, Michele Hinerasky da Silva
Publikováno v:
Neurotoxicity Research. 26:317-330
Acute stroke is a major risk for morbidity and mortality in aging population. Mitochondrion has been the focus of a wide stroke-related research. This study investigated if treatment or pre-treatment with diphenyl diselenide (PhSe)2 can prevent mitoc
Autor:
Fernando Dobrachinski, Nelson Rodrigues de Carvalho, José L. Mauriz, Edovando José Flores da Rosa, Félix Alexandre Antunes Soares, João Rocha, Javier González-Gallego, Michele Hinerasky da Silva
Publikováno v:
Neurotoxicity Research. 21:334-344
Organoselenium compounds exhibit antioxidant activity, as well as a variety of biological activities, with potential pharmacological and therapeutic applications. The aim of this study was to investigate the effect of diphenyl diselenide (PhSe)(2) in
Autor:
Edovando José Flores da Rosa, Cristiane Lenz Dalla Corte, José L. Mauriz, Félix Alexandre Antunes Soares, Cintia C. Tassi, Javier González-Gallego, Nelson Rodrigues de Carvalho, Sara Carbajo-Pescador, Michele Hinerasky da Silva
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81961 (2013)
PLoS ONE
PLoS ONE
The acute liver failure (ALF) induced by acetaminophen (APAP) is closely related to oxidative damage and depletion of hepatic glutathione, consequently changes in cell energy metabolism and mitochondrial dysfunction have been observed after APAP over
Autor:
Fernando Dobrachinski, Guilherme Pires Amaral, Nelson Rodrigues de Carvalho, Sônia Cristina Almeida da Luz, Rômulo Pillon Barcelos, Thiago Henrique Lugokenski, Glaecir Roseni Mundstock Dias, Roselei Fachinetto, Félix Alexandre Antunes Soares, Marcos A. Villetti, Aline Augusti Boligon, Michele Hinerasky da Silva, Rafael de Lima Portella, Margareth Linde Athayde
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 55
The pathology of a gastric ulcer is complex and multifactorial. Gastric ulcers affect many people around the world and its development is a result of the imbalance between aggressive and protective factors in the gastric mucosa. In this study, we eva
Autor:
João Rocha, Edovando José Flores da Rosa, Nelson Rodrigues de Carvalho, Javier González-Gallego, José L. Mauriz, Sara Carbajo-Pescador, Michele Hinerasky da Silva, Félix Alexandre Antunes Soares, Jessika Cristina Bridi
Publikováno v:
Toxicologic pathology. 40(4)
In this study, the authors evaluated the ability of diphenyl diselenide (PhSe)2 to reverse acute hepatic failure induced by acetaminophen (APAP) in mice. The animals received an APAP dose of 600 mg/kg intraperitoneally (i.p.), and then 1 hour later,