Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michele Giovinazzo"'
Publikováno v:
European Respiratory Review, Vol 31, Iss 163 (2022)
Pulmonary arterial pressure rises minimally during exercise. The pulmonary microcirculation accommodates increasing blood flow via recruitment of pulmonary capillaries and, at higher flows, by distention of already perfused capillaries. The flow tran
Externí odkaz:
https://doaj.org/article/16ba19bd2dcc49638575c8a7d73dd39b
Autor:
David, Langleben, Stylianos E, Orfanos, Benjamin D, Fox, Nathan, Messas, Michele, Giovinazzo, John D, Catravas
Publikováno v:
Journal of clinical medicine. 11(15)
Exercise-induced increases in pulmonary blood flow normally increase pulmonary arterial pressure only minimally, largely due to a reserve of pulmonary capillaries that are available for recruitment to carry the flow. In pulmonary arterial hypertensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::464559e4cfa2f772d85758fdb77c3306
https://pubmed.ncbi.nlm.nih.gov/35956182
https://pubmed.ncbi.nlm.nih.gov/35956182
Autor:
David, Langleben, Benjamin D, Fox, Stylianos E, Orfanos, Michele, Giovinazzo, John D, Catravas
Publikováno v:
European respiratory review : an official journal of the European Respiratory Society. 31(163)
Pulmonary arterial pressure rises minimally during exercise. The pulmonary microcirculation accommodates increasing blood flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf93255ffed6d684010c929122d358fd
https://pubmed.ncbi.nlm.nih.gov/35197268
https://pubmed.ncbi.nlm.nih.gov/35197268
Autor:
Michele Giovinazzo, Benjamin D. Fox, David Langleben, Robert Naeije, Stylianos E. Orfanos, John D. Catravas, Robert D. Schlesinger, Ali O. Abualsaud, Fay Blenkhorn, Lawrence G. Rudski
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 317(3)
In exercising humans, cardiac output (CO) increases, with minor increases in pulmonary artery pressure (PAP). It is unknown if the CO is accommodated via distention of already perfused capillaries or via recruitment of nonconcomitantly perfused pulmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e16f2147cf8e7ed4578cab469fecc2d
https://pubmed.ncbi.nlm.nih.gov/31242024
https://pubmed.ncbi.nlm.nih.gov/31242024
Publikováno v:
Microvascular Research. 85:46-53
Background Many cases of pulmonary arterial hypertension (PAH) are heritable and related to gene mutations in bone morphogenic receptor-2 (BMPR2). These patients consequently may have a signaling imbalance within the transforming growth factor beta (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648b452e30d4aeb56e9d55a5b877d7cb
https://doi.org/10.1016/j.mvr.2012.10.012
https://doi.org/10.1016/j.mvr.2012.10.012
Publikováno v:
Microvascular Research. 80:349-354
Abnormalities of signalling for the transforming growth factor beta (TGFβ) family of peptides, including bone morphogenic proteins (BMP), have been described in heritable pulmonary arterial hypertension (PAH). TGFβ can modulate synthesis of the vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::034b3624dbea4f407153da5b75dcdedc
https://doi.org/10.1016/j.mvr.2010.05.010
https://doi.org/10.1016/j.mvr.2010.05.010
Autor:
David Langleben, Stylianos E. Orfanos, Andrew Hirsch, John D. Catravas, Michele Giovinazzo, Apostolos Armaganidis
Publikováno v:
Journal of Thrombosis and Haemostasis. 6:1275-1280
Summary. Background: Chronic thromboembolic pulmonary hypertension (CTEPH) causes physical plugging of large pulmonary arteries as well as a distal micro-vasculopathy. Pulmonary endothelium is an active metabolic tissue in normal humans. The effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fbbeae1d2ee310b31742bb8f15b684
https://doi.org/10.1111/j.1538-7836.2008.03046.x
https://doi.org/10.1111/j.1538-7836.2008.03046.x
Autor:
Michele Giovinazzo, Fay Blenkhorn, David Langleben, Lyda Lesenko, Robert D. Schlesinger, Andrew Hirsch, Stylianos E. Orfanos, Apostolos Armaganidis, John D. Catravas
Publikováno v:
Annals of internal medicine. 162(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9f513165c04041a0ed3281474e4611
https://pubmed.ncbi.nlm.nih.gov/25599353
https://pubmed.ncbi.nlm.nih.gov/25599353
Autor:
David Langleben, Isaac Langleben, Jean-Luc Senécal, Jocelyn Dupuis, Andrew Hirsch, Michele Giovinazzo, Murray Baron
Publikováno v:
Chest. 129:689-695
Study objectives Endothelin (ET)-1 is a mediator of vascular remodeling seen in human pulmonary hypertension (PH), and it is normally cleared via endothelial ET-B receptors. Increased levels of ET-1 are found in precapillary PH, partly from increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a6d5888be75e2fde37d5ea049fc1d
https://doi.org/10.1378/chest.129.3.689
https://doi.org/10.1378/chest.129.3.689
Autor:
Michele Giovinazzo, Christina Sotiropoulou, Apostolos Armaganidis, David Langleben, Andrew Hirsch, John D. Catravas, Kim Boutet, Stylianos E. Orfanos
Publikováno v:
D26. PULMONARY VASCULAR AND RIGHT HEART PHYSIOLOGY.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0c8703751763cc9efc78f83d8d9bb35
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5746
https://doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5746