Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michele Frison"'
Autor:
Stephen P. Burr, Florian Klimm, Angelos Glynos, Malwina Prater, Pamella Sendon, Pavel Nash, Christopher A. Powell, Marie-Lune Simard, Nina A. Bonekamp, Julia Charl, Hector Diaz, Lyuba V. Bozhilova, Yu Nie, Haixin Zhang, Michele Frison, Maria Falkenberg, Nick Jones, Michal Minczuk, James B. Stewart, Patrick F. Chinnery
Publikováno v:
Cell
1229.E21
1229.E21
Mitochondrial activity differs markedly between organs, but it is not known how and when this arises. Here we show that cell lineage-specific expression profiles involving essential mitochondrial genes emerge at an early stage in mouse development, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f0cb0645b86f5d93340ecb65896a8a
Autor:
Rosella Abeti, Michele Frison, Dong Xia, Kenneth Smith, Lisa Wells, Daniela Strobbe, Federico Turkheimer, Danilo Faccenda, Paola Giunti, Marija Sajic, Manuel Rigon, Michelangelo Campanella, Katy Barnes, Heather Mortiboys, Mona Sadeghian, Britannie S. England-Rendon, Diana Cash
Publikováno v:
Molecular Psychiatry
Dysfunctional mitochondria characterise Parkinson’s Disease (PD). Uncovering etiological molecules, which harm the homeostasis of mitochondria in response to pathological cues, is therefore pivotal to inform early diagnosis and therapy in the condi
Autor:
Mark G. Waugh, Alexander Hoischen, Zsolt Urban, Eva Morava, J. Paul Simons, Lock Hock Ngu, Hans Spelbrink, Hanka Venselaar, Ron A. Wevers, Sanne van Kraaij, Bert Callewaert, Ulrich Brandt, Thatjana Gardeitchik, Raya Al-Shawi, Miski Mohamed, Daisy Dalloyaux, Shanti Balasubramaniam, Johannes M. F. G. Aerts, Michele Frison, Sergio Guerrero-Castillo, Wouter W. Kallemeijn
Publikováno v:
Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease, 43(6), 1382-1391. WILEY
JOURNAL OF INHERITED METABOLIC DISEASE
Journal of Inherited Metabolic Disease, 43, 1382-1391
Journal of Inherited Metabolic Disease, 43, 6, pp. 1382-1391
Journal of Inherited Metabolic Disease, 43(6), 1382-1391. WILEY
JOURNAL OF INHERITED METABOLIC DISEASE
Journal of Inherited Metabolic Disease, 43, 1382-1391
Journal of Inherited Metabolic Disease, 43, 6, pp. 1382-1391
Inherited cutis laxa, or inelastic, sagging skin is a genetic condition of premature and generalised connective tissue ageing, affecting various elastic components of the extracellular matrix. Several cutis laxa syndromes are inborn errors of metabol
Autor:
Natalie Sampson, Jemma Gatliff, Federico Turkheimer, Maria Soledad Alvarez, Daniel A. East, Aarti Singh, Ivana Matic, Michelangelo Campanella, Caterina Ferraina, Michele Frison
Publikováno v:
Gatliff, J, East, D A, Singh, A, Alvarez, M S, Frison, M, Matic, I, Ferraina, C, Sampson, N, Turkheimer, F & Campanella, M 2017, ' A role for TSPO in mitochondrial Ca(2+) homeostasis and redox stress signaling ', Cell Death & Disease, vol. 8, no. 6, pp. e2896 . https://doi.org/10.1038/cddis.2017.186
CELL DEATH & DISEASE
CELL DEATH & DISEASE
The 18 kDa translocator protein TSPO localizes on the outer mitochondrial membrane (OMM). Systematically overexpressed at sites of neuroinflammation it is adopted as a biomarker of brain conditions. TSPO inhibits the autophagic removal of mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a7af140d580ff3b56513b402fc674d
https://kclpure.kcl.ac.uk/en/publications/6c9a6f35-f3bc-4507-ba89-18a5ffe40dd7
https://kclpure.kcl.ac.uk/en/publications/6c9a6f35-f3bc-4507-ba89-18a5ffe40dd7
Publikováno v:
Molecular Basis for Mitochondrial Signaling ISBN: 9783319555379
Mitochondria serve a plethora of functions, beyond the essential production of ATP, that are intimately involved in the definition of cellular physiology and pathology. These roles include the buffering and decoding of signalling, induction of progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d868feb8dbf249b77df4e258c616329f
https://doi.org/10.1007/978-3-319-55539-3_11
https://doi.org/10.1007/978-3-319-55539-3_11
Autor:
Jemma, Gatliff, Daniel A, East, Aarti, Singh, Maria Soledad, Alvarez, Michele, Frison, Ivana, Matic, Caterina, Ferraina, Natalie, Sampson, Federico, Turkheimer, Michelangelo, Campanella
Publikováno v:
Cell Death & Disease
The 18 kDa translocator protein TSPO localizes on the outer mitochondrial membrane (OMM). Systematically overexpressed at sites of neuroinflammation it is adopted as a biomarker of brain conditions. TSPO inhibits the autophagic removal of mitochondri
Autor:
Michele Frison, Jemma Gatliff, Natalie Sampson, Daniel A. East, Michelangelo Campanella, Maria Soledad Alvarez, Ivana Matic, Federico Turkheimer, Aarti Singh, Caterina Ferraina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c8aaedb63dbf6122186a88ec2b0cf1
http://hdl.handle.net/2108/265658
http://hdl.handle.net/2108/265658
Publikováno v:
Biophysical Journal. 114:2a
Tuned mitochondrial physiology is fundamental for qualitative cellular function. This is particularly relevant for neurons, whose pathology is frequently associated with mitochondrial deficiencies. Defects in mitochondria are indeed key features in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468556bc1f5ec0add9378c12b8c680d0
http://hdl.handle.net/2108/206295
http://hdl.handle.net/2108/206295
Autor:
Michele Frison
Publikováno v:
Biophysical Journal. 110:473a
The Translocator Protein (TSPO), formerly known as peripheral benzodiazepine receptor, is a nuclear-encoded protein residing on the outer mitochondrial membrane1. It is commonly used in the field of biomedical imaging as a target for Positron Emissio