Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michele Dal Cin"'
Autor:
Aldo Feriani, Laura Zonzini, Laura Castelletti, Selena Nola, Michele Dal Cin, Teresa Semeraro, Sylvie Gehanne, Silvia Tomelleri, Filippo Visentini, Palmina Cavallini, Susanna Cremonesi, Annalisa Pellacani, Anna Sava, Alessia Bacchi, Andrea Wong, Simone Braggio, Luca Tarsi, Mahmud Kajbaf, Paolo Cavanni, Elisabetta Perdona, Christian Heidbreder, Luciano Marchiò, Beatrice Oliosi, Fabrizio Micheli
Publikováno v:
Journal of Medicinal Chemistry. 59:8549-8576
A novel series of 1,2,4-triazolyl 5-azaspiro[2.4]heptanes with high affinity and selectivity at the dopamine (DA) D3 receptor (D3R) is described. Some of these compounds also have high selectivity over the hERG channel and were characterized with res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e92639ff81d14ff2d424ab7f16b988a
https://doi.org/10.1021/acs.jmedchem.6b00972
https://doi.org/10.1021/acs.jmedchem.6b00972
Autor:
Michele Dal Cin, Susanna Cremonesi, Simone Braggio, Andrea Wong, Aldo Feriani, Laura Zonzini, Andrea Bernardelli, Laura Castelletti, Federica Bianchi, Filippo Visentini, Palmina Cavallini, Teresa Semeraro, Silvia Tomelleri, Luca Tarsi, Christian Heidbreder, Paolo Cavanni, Fabrizio Micheli, Beatrice Oliosi
Publikováno v:
Bioorganicmedicinal chemistry. 24(8)
A novel series of 1,2,4-triazolyl octahydropyrrolo[2,3-b]pyrroles showing high affinity and selectivity at the DA D3 receptor is reported here. Compounds endowed with high selectivity over the hERG channel were identified and their pharmacokinetic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a8aa1d20afd7d4e0b510faa16afaa5
https://pubmed.ncbi.nlm.nih.gov/26951894
https://pubmed.ncbi.nlm.nih.gov/26951894
Autor:
Sylvie Gehanne, Michele Dal Cin, and Pierfausto Seneci, Nadia Conti, Alfredo Paio, Alessio Zaramella
Publikováno v:
Journal of Combinatorial Chemistry. 3:410-420
The presence of dansyl or dabsyl chromogenic moieties in a solid-phase analytical construct, an assembly of linkers/spacers/sensitizers for improving analytical characterization, allows the accurate estimation of products from solid-phase synthesis b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0035b6e96812ccd292af027b1138b089
https://doi.org/10.1021/cc0001147
https://doi.org/10.1021/cc0001147
Autor:
Martyn Deal, T. Rossi, Georg Terstappen, Michael H. Rabinowitz, Pierfausto Seneci, Michele Dal Cin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1007-1010
A novel solid-phase/solution-phase strategy for the synthesis of neuroimmunophilin ligands based on GPI 1046 was developed. The synthesis employs a solid-phase esterification strategy followed by a solution-phase pyruvic amide formation to produce mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc207846061d10c6bffb8c99e0d3cf10
https://doi.org/10.1016/s0960-894x(00)00104-9
https://doi.org/10.1016/s0960-894x(00)00104-9
Autor:
Andrea Togninelli, Sonia Delle Fratte, Milan Mesic, Emiliano Castiglioni, Luigi Piero Stasi, Mario Smehil, Massimo Gianotti, Maurizio Botta, Michele Dal-Cin, Renzo Carletti, Francesca Pavone, Laura Piccoli, Mark Wigglesworth, Denana Korajac, Slavko Rast, Maja Roščić, Stephen J. Brough, Anna Sava, Corrado Corti, Giancarlo Merlo, Marija Lovrić
Publikováno v:
Journal of medicinal chemistry. 53(21)
Histamine H(1) and serotonin 5-HT(2A) receptors mediate two different mechanisms involved in sleep regulation: H(1) antagonists are sleep inducers, while 5-HT(2A) antagonists are sleep maintainers. Starting from 9'a, a novel spirotetracyclic compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f441b5897e4354fcfc1d72f68a14507c
https://pubmed.ncbi.nlm.nih.gov/20942472
https://pubmed.ncbi.nlm.nih.gov/20942472
Autor:
Russell J. Thomas, Claudia Cardinaletti, Laura Mattioli, Mario Giannella, Fabio Del Bello, Ugo Zanelli, Marina Perfumi, Francesca Ghelfi, Michele Dal Cin, Maria Pigini, Wilma Quaglia, Alessandro Piergentili, Carla Marchioro
Publikováno v:
Journal of medicinal chemistry. 53(21)
The functional in vitro study of the enantiomers of imidazolines 4-7 highlighted the role played by the nature of the ortho phenyl substituent in determining the preferred α(2C)-AR configuration. Indeed, the (S) enantiomers of 4-6 or (R) enantiomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf3d7221061ac43412252fbfe612300
https://pubmed.ncbi.nlm.nih.gov/20925410
https://pubmed.ncbi.nlm.nih.gov/20925410
Autor:
Romano Di Fabio, Raffaella Spinosa, Mark Wigglesworth, Massimo Gianotti, Michele Dal Cin, Emiliano Castiglioni, Giancarlo Merlo, Carla Marchioro, Stephen J. Brough, Maurizio Botta, Andrea Togninelli, Fiona Brown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce126531e48cbfe97afa3d0bb432e93e
http://hdl.handle.net/11365/9488
http://hdl.handle.net/11365/9488
Autor:
Michele Dal Cin, Alessio Zaramella, Ornella Curcuruto, Daniele Marton, Tania Rizzetto, Paolo Pastore
Publikováno v:
Rapid communications in mass spectrometry : RCM. 15(22)
The composition of a commercial dehydroascorbic acid (DA) solution at pH 2 was investigated by liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS) to establish the nature of its different form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871f3128a3fcfb0798f53da107b68e78
https://pubmed.ncbi.nlm.nih.gov/11746868
https://pubmed.ncbi.nlm.nih.gov/11746868