Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Michele C, Madigan"'
Autor:
Rogier J. Nell, Nino V. Menger, Mieke Versluis, Gregorius P. M. Luyten, Robert M. Verdijk, Michele C. Madigan, Martine J. Jager, Pieter A. van der Velden
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Activating Gαq signalling mutations are considered an early event in the development of uveal melanoma. Whereas most tumours harbour a mutation in GNAQ or GNA11, CYSLTR2 (encoding G-protein coupled receptor CysLT2R) forms a rare
Externí odkaz:
https://doaj.org/article/b4370d2a344542988969c853605cedea
Autor:
Samuel C. Eggenberger, Natalie L. James, Cherry Ho, Steven S. Eamegdool, Veronika Tatarinoff, Naomi A. Craig, Barry S. Gow, Susan Wan, Christopher W.D. Dodds, Donna La Hood, Aaron Gilmour, Shannon L. Donahoe, Mark Krockenberger, Krishna Tumuluri, Melville J. da Cruz, John R. Grigg, Peter McCluskey, Nigel H. Lovell, Michele C. Madigan, Adrian T. Fung, Gregg J. Suaning
Publikováno v:
Data in Brief, Vol 39, Iss , Pp 107634- (2021)
The data presented here are related and supplementary data to the research article “Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep” [1]. In Eggenberger e
Externí odkaz:
https://doaj.org/article/63829d9e51c44b09b0e506d4d9a1d8d7
Autor:
Yingying Chen, Nathan J. Coorey, Meixia Zhang, Shaoxue Zeng, Michele C. Madigan, Xinyuan Zhang, Mark C. Gillies, Ling Zhu, Ting Zhang
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 942 (2022)
The human retina, which is part of the central nervous system, has exceptionally high energy demands that requires an efficient metabolism of glucose, lipids, and amino acids. Dysregulation of retinal metabolism disrupts local energy supply and redox
Externí odkaz:
https://doaj.org/article/a4757895ac1243f7a25b0566e7659e21
Autor:
Shaoxue Zeng, Ting Zhang, Michele C. Madigan, Nilisha Fernando, Riemke Aggio-Bruce, Fanfan Zhou, Matthew Pierce, Yingying Chen, Lianlin Huang, Riccardo Natoli, Mark C. Gillies, Ling Zhu
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Interphotoreceptor retinoid-binding protein (IRBP), also known as retinol binding protein 3 (RBP3), is a lipophilic glycoprotein specifically secreted by photoreceptors. Enriched in the interphotoreceptor matrix (IPM) and recycled by the retinal pigm
Externí odkaz:
https://doaj.org/article/35c009e72c364723a4b6a061812fc752
Autor:
Jingjing You, Susan M. Corley, Li Wen, Chris Hodge, Roland Höllhumer, Michele C. Madigan, Marc R. Wilkins, Gerard Sutton
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/d61d9849123e4eab8eb8066d12e8092a
Autor:
Wenying Shu, Xue Zhu, Ke Wang, Svetlana Cherepanoff, R. Max Conway, Michele C. Madigan, Hong Zhu, Ling Zhu, Michael Murray, Fanfan Zhou
Publikováno v:
Cellular Oncology. 45:601-619
Purpose Uveal melanoma (UM) is the most common intraocular malignancy in adults with a poor prognosis and a high recurrence rate. Currently there is no effective treatment for UM. Multi-kinase inhibitors targeting dysregulated pro-tumorigenic signall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fa48585cd883824c6b1e573af794fd
https://doi.org/10.1007/s13402-022-00686-5
https://doi.org/10.1007/s13402-022-00686-5
Autor:
Ting Zhang, Ling Zhu, Michele C Madigan, Wei Liu, Weiyong Shen, Svetlana Cherepanoff, Fanfan Zhou, Shaoxue Zeng, Jianhai Du, Mark C Gillies
Publikováno v:
eLife, Vol 8 (2019)
The human macula is more susceptible than the peripheral retina to developing blinding conditions such as age-related macular degeneration, diabetic retinopathy. A key difference between them may be the nature of their Müller cells. We found primary
Externí odkaz:
https://doaj.org/article/2448b4f984bc421eb82e42f57438ca08
Autor:
Stanley Zhang, Ke Wang, Xue Zhu, Svetlana Cherepanoff, R. Max Conway, Michele C. Madigan, Ling Zhu, Michael Murray, Fanfan Zhou
Publikováno v:
Biochimie. 197:9-18
Uveal melanoma (UM) is a highly metastatic ocular cancer that arises from the melanocytes of the uveal tract (the choroid, ciliary body and iris). Despite a growing understanding of UM biology, effective systemic treatments are currently lacking and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b310d22dfa54e2a4ceb04bf00842e7bb
https://doi.org/10.1016/j.biochi.2022.01.017
https://doi.org/10.1016/j.biochi.2022.01.017
Autor:
Rene Cheung, Angelica Ly, Paula Katalinic, Minas Theodore Coroneo, Andrew Chang, Michael Kalloniatis, Michele C. Madigan, Lisa Nivison-Smith
Publikováno v:
Seminars in Ophthalmology. 37:554-582
Certain peripheral retinal degenerations pose a significant risk to vision and require prompt detection and management. Other historically "benign" peripheral lesions are being recognised as clinically significant due to their associations with ocula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5efda99bfe3c0faf0b390e129f04f55
https://doi.org/10.1080/08820538.2022.2039222
https://doi.org/10.1080/08820538.2022.2039222
Autor:
Wenying Shu, Janney Z Wang, Xue Zhu, Ke Wang, Svetlana Cherepanoff, R. Max Conway, Michele C Madigan, Li-Anne Lim, Hong Zhu, Ling Zhu, Michael Murray, Fanfan Zhou
Although uveal melanoma (UM) is rare, it is the principal type of intraocular malignancy. Up to 50% of UM patients develop metastatic disease with low chances of survival beyond 18 months. At present there are no drugs that are effective in the treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1b7938302086b23e8d6daa1a18d718
https://doi.org/10.21203/rs.3.rs-2295786/v1
https://doi.org/10.21203/rs.3.rs-2295786/v1
