Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Michele Biscuola"'
Autor:
Mercedes Delgado-García, Birgit Weynand, Lourdes Gómez-Izquierdo, María José Hernández, Ángela María Blanco, Mar Varela, Xavier Matias-Guiu, Ernest Nadal, Bélgica Márquez-Lobo, Ana Alarcão, Enrique de Álava, Michele Biscuola
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Detection of epidermal growth factor receptor (EGFR) mutations in exons 18–21 is recommended in all patients with advanced Non-small-cell lung carcinoma due to the demonstrated efficiency of the standard therapy with tyrosine ki
Externí odkaz:
https://doaj.org/article/931a3412f3ce49e3a946c98467c818ef
Autor:
Ana Teresa Amaral, Maria Cristina Manara, Dagmar Berghuis, José Luis Ordóñez, Michele Biscuola, Maria Angeles Lopez-García, Daniel Osuna, Enrico Lucarelli, Francesco Alviano, Arjan Lankester, Katia Scotlandi, Enrique de Álava
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e85814 (2014)
BackgroundEwing Sarcoma (EWS) is a mesenchymal-derived tumor that generally arises in bone and soft tissue. Intensive research regarding the pathogenesis of EWS has been insufficient to pinpoint the early events of Ewing sarcomagenesis. However, the
Externí odkaz:
https://doaj.org/article/463f0eb937254aa4ba9bedb12bfa41eb
Autor:
Esther Conde, Ana Suárez-Gauthier, Amparo Benito, Pilar Garrido, Rosario García-Campelo, Michele Biscuola, Luis Paz-Ares, David Hardisson, Javier de Castro, M Carmen Camacho, Delvys Rodriguez-Abreu, Ihab Abdulkader, Josep Ramirez, Noemí Reguart, Marta Salido, Lara Pijuán, Edurne Arriola, Julián Sanz, Victoria Folgueras, Noemí Villanueva, Javier Gómez-Román, Manuel Hidalgo, Fernando López-Ríos
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107200 (2014)
BackgroundBased on the excellent results of the clinical trials with ALK-inhibitors, the importance of accurately identifying ALK positive lung cancer has never been greater. However, there are increasing number of recent publications addressing disc
Externí odkaz:
https://doaj.org/article/a2ee3e16eccc4c4487381ac1367b8191
Autor:
María Ángeles Castilla, Juan Díaz-Martín, David Sarrió, Laura Romero-Pérez, María Ángeles López-García, Begoña Vieites, Michele Biscuola, Susana Ramiro-Fuentes, Clare M Isacke, José Palacios
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47709 (2012)
The epithelial to mesenchymal transition (EMT) contributes to tumor invasion and metastasis in a variety of cancer types. In human breast cancer, gene expression studies have determined that basal-B/claudin-low and metaplastic cancers exhibit EMT-rel
Externí odkaz:
https://doaj.org/article/da20a03046994dec89b233bde84025ff
Autor:
Thomas Depoilly, Simon Garinet, Léon C. van Kempen, Ed Schuuring, Sergi Clavé, Beatriz Bellosillo, Cristiana Ercolani, Simonetta Buglioni, Janna Siemanowski, Sabine Merkelbach-Bruse, Verena Tischler, Melanie-Christin Demes, Henry Paridaens, Catherine Sibille, Vincent Thomas de Montpreville, Etienne Rouleau, Artur Bartczak, Monika Pasieka-Lis, Ryan Yee Wei Teo, Khoon Leong Chuah, Marta Barbosa, Carlos Quintana, Michele Biscuola, Mercedes Delgado-Garcia, Davide Vacirca, Alessandra Rappa, Matthew Cashmore, Matthew Smith, Piotr Jasionowicz, Adam Meeney, Patrice Desmeules, Benoit Terris, Audrey Mansuet-Lupo
Publikováno v:
Journal of molecular diagnostics, 24(9), 1021-1030. ELSEVIER SCIENCE INC
Targeted therapy in lung cancer requires the assessment of multiple oncogenic driver alterations, including fusion genes. This retrospective study evaluated the Idylla GeneFusion prototype, an automated and ease-of-use (
Autor:
Enrique de Álava, Joseph A. Ludwig, Ángel M. Carcaboso, Myriam Fabre, Laureano Simón, Klaus Pfizenmaier, Roland Kontermann, Oliver Seifert, Keri Schadler, Branko Cuglievan, Jaume Mora, Cristina Ferrer, Michele Biscuola, María José Robles-Frías, Gema Civantos-Jubera, Maria Lopez-Alvarez, Laura Romero-Pérez, Juan Diaz-Martin, Carmen Jordan-Perez, Saioa Domínguez, José Luis Ordóñez, Helena Castillo-Ecija, Brian A. Menegaz, Salah-Eddine Lamhamedi-Cherradi, Ana Teresa Amaral, Pilar Puerto-Camacho
Supplementary Material & Methods, Figure Legends and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd417750e3901010bac209354fb6511
https://doi.org/10.1158/1078-0432.22472516
https://doi.org/10.1158/1078-0432.22472516
Autor:
Enrique de Álava, Joseph A. Ludwig, Ángel M. Carcaboso, Myriam Fabre, Laureano Simón, Klaus Pfizenmaier, Roland Kontermann, Oliver Seifert, Keri Schadler, Branko Cuglievan, Jaume Mora, Cristina Ferrer, Michele Biscuola, María José Robles-Frías, Gema Civantos-Jubera, Maria Lopez-Alvarez, Laura Romero-Pérez, Juan Diaz-Martin, Carmen Jordan-Perez, Saioa Domínguez, José Luis Ordóñez, Helena Castillo-Ecija, Brian A. Menegaz, Salah-Eddine Lamhamedi-Cherradi, Ana Teresa Amaral, Pilar Puerto-Camacho
Purpose:Endoglin (ENG; CD105) is a coreceptor of the TGFβ family that is highly expressed in proliferating endothelial cells. Often coopted by cancer cells, ENG can lead to neo-angiogenesis and vasculogenic mimicry in aggressive malignancies. It exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dc25587bdf8d7dbfcb36456efabe8b
https://doi.org/10.1158/1078-0432.c.6528251.v1
https://doi.org/10.1158/1078-0432.c.6528251.v1
Autor:
Enrique de Álava, Joseph A. Ludwig, Ángel M. Carcaboso, Myriam Fabre, Laureano Simón, Klaus Pfizenmaier, Roland Kontermann, Oliver Seifert, Keri Schadler, Branko Cuglievan, Jaume Mora, Cristina Ferrer, Michele Biscuola, María José Robles-Frías, Gema Civantos-Jubera, Maria Lopez-Alvarez, Laura Romero-Pérez, Juan Diaz-Martin, Carmen Jordan-Perez, Saioa Domínguez, José Luis Ordóñez, Helena Castillo-Ecija, Brian A. Menegaz, Salah-Eddine Lamhamedi-Cherradi, Ana Teresa Amaral, Pilar Puerto-Camacho
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8ddef117b2dfdf57193d6ad98ffe5a
https://doi.org/10.1158/1078-0432.22472519.v1
https://doi.org/10.1158/1078-0432.22472519.v1
Autor:
Edurne Arriola, Reyes Bernabé, Rosario García Campelo, Michele Biscuola, Ana Belén Enguita, Fernando López-Ríos, Rafael Martínez, Laura Mezquita, Sarai Palanca, María Jesús Pareja, Jon Zugazagoitia, Natalia Arrabal, J. Francisco García, David Carcedo, Enrique de Álava
Publikováno v:
JCO Precision Oncology.
PURPOSE The aim of this study was to assess the cost-effectiveness of using next-generation sequencing (NGS) versus single-gene testing (SgT) for the detection of genetic molecular subtypes and oncogenic markers in patients with advanced non–small-
Autor:
Belén Pérez-Mies, Tamara Caniego-Casas, Irene Carretero-Barrio, Michele Biscuola, María A. López-García, David Hardisson, Marta Rosas, María J. López Rodríguez, Eva Cristóbal, David Pizarro, Juan M. Rosa-Rosa, José Palacios
The relationship between the ductal and lobular components of invasive ductolobular carcinomas (IDLC) has not been fully elucidated. In this study, the molecular alterations of both components were analyzed in a series of 20 IDLC that were selected,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915bbf8b0bbd8e253e3579296ca59ec5
https://hdl.handle.net/10668/19859
https://hdl.handle.net/10668/19859