Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michele Angelo Di Bari"'
Autor:
Alba Marín-Moreno, Sylvie L. Benestad, Tomas Barrio, Laura Pirisinu, Juan Carlos Espinosa, Linh Tran, Alvina Huor, Michele Angelo Di Bari, Hasier Eraña, Ben C. Maddison, Claudia D’Agostino, Natalia Fernández-Borges, Sara Canoyra, Nuria Jerez-Garrido, Joaquín Castilla, John Spiropoulos, Keith Bishop, Kevin C. Gough, Romolo Nonno, Jorn Våge, Olivier Andréoletti, Juan María Torres
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem of the animal. Two different western blotting tests were conducted independently
Externí odkaz:
https://doaj.org/article/51a3b8f500ba47a290cef12832a53307
Autor:
Laura Pirisinu, Michele Angelo Di Bari, Claudia D'Agostino, Ilaria Vanni, Geraldina Riccardi, Stefano Marcon, Gabriele Vaccari, Barbara Chiappini, Sylvie L Benestad, Umberto Agrimi, Romolo Nonno
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010646 (2022)
Prions are infectious agents that replicate through the autocatalytic misfolding of the cellular prion protein (PrPC) into infectious aggregates (PrPSc) causing fatal neurodegenerative diseases in humans and animals. Prions exist as strains, which ar
Externí odkaz:
https://doaj.org/article/2b83060431654ed9b2c52765a6701d8e
Autor:
Rosalia Bruno, Geraldina Riccardi, Floriana Iacobone, Flavia Chiarotti, Laura Pirisinu, Ilaria Vanni, Stefano Marcon, Claudia D’Agostino, Matteo Giovannelli, Piero Parchi, Umberto Agrimi, Romolo Nonno, Michele Angelo Di Bari
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 757 (2023)
Reactive astrogliosis is one of the pathological hallmarks of prion diseases. Recent studies highlighted the influence of several factors on the astrocyte phenotype in prion diseases, including the brain region involved, the genotype backgrounds of t
Externí odkaz:
https://doaj.org/article/38dc673438dc4a329f6c1c20585b74c8
Autor:
Rosalia Bruno, Laura Pirisinu, Geraldina Riccardi, Claudia D’Agostino, Elena De Cecco, Giuseppe Legname, Franco Cardone, Pierluigi Gambetti, Romolo Nonno, Umberto Agrimi, Michele Angelo Di Bari
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1537 (2022)
Gerstmann–Sträussler–Scheinker disease (GSS) is a rare genetic prion disease. A large GSS kindred linked to the serine-for-phenylalanine substitution at codon 198 of the prion protein gene (GSS-F198S) is characterized by conspicuous accumulation
Externí odkaz:
https://doaj.org/article/db4286241835496082a9a843e667f2ee
Autor:
Romolo Nonno, Silvio Notari, Michele Angelo Di Bari, Ignazio Cali, Laura Pirisinu, Claudia d’Agostino, Laura Cracco, Diane Kofskey, Ilaria Vanni, Jody Lavrich, Piero Parchi, Umberto Agrimi, Pierluigi Gambetti
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 1, Pp 73-81 (2019)
Variably protease-sensitive prionopathy (VPSPr), a recently described human sporadic prion disease, features a protease-resistant, disease-related prion protein (resPrPD) displaying 5 fragments reminiscent of Gerstmann-Sträussler-Scheinker disease.
Externí odkaz:
https://doaj.org/article/ad97e37aa0e14c208f6fcf1cda0903b4
Autor:
Baaissa Babelhadj, Michele Angelo Di Bari, Laura Pirisinu, Barbara Chiappini, Semir Bechir Suheil Gaouar, Geraldina Riccardi, Stefano Marcon, Umberto Agrimi, Romolo Nonno, Gabriele Vaccari
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 6, Pp 1029-1036 (2018)
Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE). After the BSE epidemic, and the associated human infections, began
Externí odkaz:
https://doaj.org/article/ee600e683e034f7f87844882e73f59fc
Autor:
Cassandra M Burke, Daniel J Walsh, Alexander D Steele, Umberto Agrimi, Michele Angelo Di Bari, Joel C Watts, Surachai Supattapone
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007662 (2019)
The protein-only hypothesis predicts that infectious mammalian prions are composed solely of PrPSc, a misfolded conformer of the normal prion protein, PrPC. However, protein-only PrPSc preparations lack significant levels of prion infectivity, leadin
Externí odkaz:
https://doaj.org/article/faa03f4b1582437aac6477a3c8949854
Autor:
Romolo Nonno, Umberto Agrimi, Claudia D'Agostino, Michele Angelo Di Bari, Stefano Marcon, Laura Pirisinu
Publikováno v:
Pathogens, Vol 2, Iss 3, Pp 446-456 (2013)
Prions exist as different strains exhibiting distinct disease phenotypes. Currently, the identification of prion strains is still based on biological strain typing in rodents. However, it has been shown that prion strains may be associated with disti
Externí odkaz:
https://doaj.org/article/5f7bc653385d4f4e91e510f1c7ee3514
Autor:
Ilaria Vanni, Sergio Migliore, Gian Mario Cosseddu, Michele Angelo Di Bari, Laura Pirisinu, Claudia D'Agostino, Geraldina Riccardi, Umberto Agrimi, Romolo Nonno
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006016 (2016)
It is widely known that prion strains can mutate in response to modification of the replication environment and we have recently reported that prion mutations can occur in vitro during amplification of vole-adapted prions by Protein Misfolding Cyclic
Externí odkaz:
https://doaj.org/article/b464e3b005d0409b82aab3fbc2de3214
Autor:
Laura Pirisinu, Sergio Migliore, Michele Angelo Di Bari, Elena Esposito, Thierry Baron, Claudia D’Agostino, Luigi De Grossi, Gabriele Vaccari, Umberto Agrimi, Romolo Nonno
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 4, Pp 695-698 (2011)
Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation. Thi
Externí odkaz:
https://doaj.org/article/12e5920117fb47ea853d754c73e94b94