Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Michele A. La Merrill"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115756- (2024)
Triphenyl phosphate (TPhP), a widely used organophosphate-flame retardant, is ubiquitously found in household environments and may adversely affect human health. Evidence indicates that TPhP exposure causes metabolic dysfunctions in vivo; however, th
Externí odkaz:
https://doaj.org/article/46465d227f264879a89db701ec1d8e21
Autor:
Annalise N. vonderEmbse, Sarah E. Elmore, Kyle B. Jackson, Beth A. Habecker, Katherine E. Manz, Kurt D. Pennell, Pamela J. Lein, Michele A. La Merrill
Publikováno v:
Environmental Health, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Exposure to the bioaccumulative pesticide dichlorodiphenyltrichloroethane (DDT) and its metabolite dichlorodiphenyldichloroethylene (DDE) has been associated with increased risk of insulin resistance and obesity in humans and expe
Externí odkaz:
https://doaj.org/article/5b7e36c61c2f4a7ea34b66c4dd6dc53d
Autor:
Juliann Jugan, P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Kärrman, Lars Lind, Michele A. La Merrill
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background Lipoproteins at aberrant levels are known to play a role in cardiovascular disease. The metabolite of the insecticide dichlorodiphenyltrichloroethane (DDT), p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE), physically associat
Externí odkaz:
https://doaj.org/article/7a9c749127424c6ea0fefac008a26b5f
Autor:
Christoph F. A. Vogel, Gwendal Lazennec, Sarah Y. Kado, Carla Dahlem, Yi He, Alejandro Castaneda, Yasuhiro Ishihara, Christian Vogeley, Andrea Rossi, Thomas Haarmann-Stemmann, Juliann Jugan, Hidetoshi Mori, Alexander D. Borowsky, Michele A. La Merrill, Colleen Sweeney
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer. While the repressor protein of the AhR (AhRR) blocks the canonical AhR pathway,
Externí odkaz:
https://doaj.org/article/23185571887c41edb97383b865a509ef
Autor:
Damaskini Valvi, Douglas I. Walker, Thomas Inge, Scott M. Bartell, Todd Jenkins, Michael Helmrath, Thomas R. Ziegler, Michele A. La Merrill, Sandrah P. Eckel, David Conti, Yongliang Liang, Dean P. Jones, Rob McConnell, Leda Chatzi
Publikováno v:
Environment International, Vol 143, Iss , Pp 105957- (2020)
Background: Advances in untargeted metabolomic technologies have great potential for insight into adverse metabolic effects underlying exposure to environmental chemicals. However, important challenges need to be addressed, including how biological r
Externí odkaz:
https://doaj.org/article/76a0d6858d014a678c85b432a0ee3e8b
Autor:
Sarah E. Elmore, Michele A. La Merrill
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
There is increasing evidence supporting the characterization of the pesticide DDT and its metabolite, DDE, as obesogens and metabolic disruptors. Elucidating the mechanism is critical to understanding whether the association of DDT and DDE with obesi
Externí odkaz:
https://doaj.org/article/ebd7edbea4444e9d8d1db7473f616ede
Publikováno v:
Toxicology Reports, Vol 2, Iss C, Pp 990-995 (2015)
Dichlorodiphenyltrichloroethane (DDT) and its metabolites accumulate in adipose tissue through dietary exposure, and have been proposed to contribute to the development of abdominal obesity, insulin resistance and dyslipidemia. Toxicity may also resu
Externí odkaz:
https://doaj.org/article/5ba696f2dccb4de0b5b46c0130e7c57c
Autor:
Juliann A. Jugan, Sarah Elmore, Kyle Jackson, Annalise vonderEmbse, Scott Tiscione, Michele A. La Merrill
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Toxicology.
Autor:
Jason H Tong, Sarah Elmore, Shenq-Shyang Huang, Phum Tachachartvanich, Katherine Manz, Kurt Pennell, Machelle D Wilson, Alexander Borowsky, Michele A La Merrill
Publikováno v:
Endocrinology
Methylparaben (MP) and propylparaben (PP) are commonly used as food, cosmetic, and drug preservatives. These parabens are detected in the majority of US women and children, bind and activate estrogen receptors (ER), and stimulate mammary tumor cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a330e888a263c43c11bdd9411d558bb9
https://europepmc.org/articles/PMC10205179/
https://europepmc.org/articles/PMC10205179/
Autor:
Julia S. Mouat, Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill, Hans-Joachim Lehmler, Michael P. Jones, Pamela J. Lein, Rebecca J. Schmidt, Janine M. LaSalle
Publikováno v:
Environmental research. 220
BackgroundGestational exposure to polychlorinated biphenyls (PCBs) has been associated with elevated risk for neurodevelopmental disorders. The mechanism of risk is unclear but may involve placental epigenetics. Prior studies have associated differen