Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Michele A Di Bari"'
Autor:
Cassandra M Burke, Daniel J Walsh, Kenneth M K Mark, Nathan R Deleault, Koren A Nishina, Umberto Agrimi, Michele A Di Bari, Surachai Supattapone
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008495 (2020)
Prion diseases are caused by the misfolding of a host-encoded glycoprotein, PrPC, into a pathogenic conformer, PrPSc. Infectious prions can exist as different strains, composed of unique conformations of PrPSc that generate strain-specific biological
Externí odkaz:
https://doaj.org/article/406d5eb819124d0c8c142131103deceb
Autor:
Hasier Eraña, Jorge M Charco, Michele A Di Bari, Carlos M Díaz-Domínguez, Rafael López-Moreno, Enric Vidal, Ezequiel González-Miranda, Miguel A Pérez-Castro, Sandra García-Martínez, Susana Bravo, Natalia Fernández-Borges, Mariví Geijo, Claudia D'Agostino, Joseba Garrido, Jifeng Bian, Anna König, Boran Uluca-Yazgi, Raimon Sabate, Vadim Khaychuk, Ilaria Vanni, Glenn C Telling, Henrike Heise, Romolo Nonno, Jesús R Requena, Joaquín Castilla
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008117 (2019)
The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long hindered due to certain particularities of thes
Externí odkaz:
https://doaj.org/article/215467d1d4f44efeb809d884605f8666
Autor:
Alba Marín-Moreno, Sylvie L. Benestad, Tomas Barrio, Laura Pirisinu, Juan Carlos Espinosa, Linh Tran, Alvina Huor, Michele Angelo Di Bari, Hasier Eraña, Ben C. Maddison, Claudia D’Agostino, Natalia Fernández-Borges, Sara Canoyra, Nuria Jerez-Garrido, Joaquín Castilla, John Spiropoulos, Keith Bishop, Kevin C. Gough, Romolo Nonno, Jorn Våge, Olivier Andréoletti, Juan María Torres
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem of the animal. Two different western blotting tests were conducted independently
Externí odkaz:
https://doaj.org/article/51a3b8f500ba47a290cef12832a53307
Autor:
Romolo Nonno, Michele A Di Bari, Franco Cardone, Gabriele Vaccari, Paola Fazzi, Giacomo Dell'Omo, Claudia Cartoni, Loredana Ingrosso, Aileen Boyle, Roberta Galeno, Marco Sbriccoli, Hans-Peter Lipp, Moira Bruce, Maurizio Pocchiari, Umberto Agrimi
Publikováno v:
PLoS Pathogens, Vol 2, Iss 2, p e12 (2006)
Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model. We report that the efficiency of primary transmission of prions from Creutzfeldt-Jakob diseas
Externí odkaz:
https://doaj.org/article/545a1b1acbf7493ab3bccb4b17b37ca0
Autor:
Laura Pirisinu, Michele Angelo Di Bari, Claudia D'Agostino, Ilaria Vanni, Geraldina Riccardi, Stefano Marcon, Gabriele Vaccari, Barbara Chiappini, Sylvie L Benestad, Umberto Agrimi, Romolo Nonno
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010646 (2022)
Prions are infectious agents that replicate through the autocatalytic misfolding of the cellular prion protein (PrPC) into infectious aggregates (PrPSc) causing fatal neurodegenerative diseases in humans and animals. Prions exist as strains, which ar
Externí odkaz:
https://doaj.org/article/2b83060431654ed9b2c52765a6701d8e
Autor:
Maxime Bélondrade, Simon Nicot, Charly Mayran, Lilian Bruyere-Ostells, Florian Almela, Michele A. Di Bari, Etienne Levavasseur, Joel C. Watts, Chantal Fournier-Wirth, Sylvain Lehmann, Stéphane Haïk, Romolo Nonno, Daisy Bougard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Unlike variant Creutzfeldt–Jakob disease prions, sporadic Creutzfeldt–Jakob disease prions have been shown to be difficult to amplify in vitro by protein misfolding cyclic amplification (PMCA). We assessed PMCA of pathological prion prot
Externí odkaz:
https://doaj.org/article/49816cda18ac44b7b8c29880c7045392
Autor:
Romolo Nonno, Silvio Notari, Michele Angelo Di Bari, Ignazio Cali, Laura Pirisinu, Claudia d’Agostino, Laura Cracco, Diane Kofskey, Ilaria Vanni, Jody Lavrich, Piero Parchi, Umberto Agrimi, Pierluigi Gambetti
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 1, Pp 73-81 (2019)
Variably protease-sensitive prionopathy (VPSPr), a recently described human sporadic prion disease, features a protease-resistant, disease-related prion protein (resPrPD) displaying 5 fragments reminiscent of Gerstmann-Sträussler-Scheinker disease.
Externí odkaz:
https://doaj.org/article/ad97e37aa0e14c208f6fcf1cda0903b4
Autor:
Laura Pirisinu, Linh Tran, Barbara Chiappini, Ilaria Vanni, Michele A. Di Bari, Gabriele Vaccari, Turid Vikøren, Knut Ivar Madslien, Jørn Våge, Terry Spraker, Gordon Mitchell, Aru Balachandran, Thierry Baron, Cristina Casalone, Christer M. Rolandsen, Knut H. Røed, Umberto Agrimi, Romolo Nonno, Sylvie L. Benestad
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 12, Pp 2210-2218 (2018)
Chronic wasting disease (CWD) persists in cervid populations of North America and in 2016 was detected for the first time in Europe in a wild reindeer in Norway. We report the detection of CWD in 3 moose (Alces alces) in Norway, identified through a
Externí odkaz:
https://doaj.org/article/cbedbb536e40440da7ec075137b07e66
Autor:
Baaissa Babelhadj, Michele Angelo Di Bari, Laura Pirisinu, Barbara Chiappini, Semir Bechir Suheil Gaouar, Geraldina Riccardi, Stefano Marcon, Umberto Agrimi, Romolo Nonno, Gabriele Vaccari
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 6, Pp 1029-1036 (2018)
Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE). After the BSE epidemic, and the associated human infections, began
Externí odkaz:
https://doaj.org/article/ee600e683e034f7f87844882e73f59fc
Autor:
Cassandra M Burke, Daniel J Walsh, Alexander D Steele, Umberto Agrimi, Michele Angelo Di Bari, Joel C Watts, Surachai Supattapone
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007662 (2019)
The protein-only hypothesis predicts that infectious mammalian prions are composed solely of PrPSc, a misfolded conformer of the normal prion protein, PrPC. However, protein-only PrPSc preparations lack significant levels of prion infectivity, leadin
Externí odkaz:
https://doaj.org/article/faa03f4b1582437aac6477a3c8949854