Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michele A, Promo"'
Autor:
Dean Messing, Brian S. Hickory, Alan G. Benson, Matthew J. Saabye, Jeff Hitchcock, Heather M. Madsen, Devadas Balekudru, Shaun R. Selness, Richard C. Durley, Laura D. Marrufo, Gary D. Anderson, Li Xing, Kevin D. Jerome, Michael Hepperle, Christie Lance Christopher, Rajesh V. Devraj, Elizabeth G. Webb, Thomas Owen, Ravi G. Kurumbail, Edgardo Alvira, Jeffrey L. Hirsch, Joseph B. Monahan, Paul V. Rucker, Boehm Terri L, Blevis-Bal Radhika M, Huey S. Shieh, John K. Walker, John F. Schindler, Michele A. Promo, Win Naing, Sheri L. Bonar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4059-4065
A series of N-aryl pyridinone inhibitors of p38 mitogen activated protein (MAP) kinase were designed and prepared based on the screening hit SC-25028 (1) and structural comparisons to VX-745 (5). The focus of the investigation targeted the dependence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57328f6e5ea96fc972d684f2e92281c
https://doi.org/10.1016/j.bmcl.2011.04.120
https://doi.org/10.1016/j.bmcl.2011.04.120
3-Methyl-4H-[1,2,4]-oxadiazol-5-one: a versatile synthon for protecting monosubstituted acetamidines
Autor:
Jeffery S. Snyder, James A. Sikorski, Michele A. Promo, Jane L. Wang, Katherine E. Palmquist, Alan E. Moormann, Mark A. Massa, Jeffrey A. Scholten, R. Keith Webber
Publikováno v:
Tetrahedron. 60:10907-10914
The utilization of 3-methyl-4H-[1,2,4]-oxadiazol-5-one as a versatile protected acetamidine is demonstrated through employment in a variety of synthetic sequences. The potassium salt ( 2a ) or the neutral form ( 2b ) is alternatively shown to be supe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21e3af81b43f1cbb052c362752de440e
https://doi.org/10.1016/j.tet.2004.09.030
https://doi.org/10.1016/j.tet.2004.09.030
Autor:
Jane L. Wang, Michael B. Tollefson, Margaret L. Grapperhaus, James A. Sikorski, Richard C. Durley, Monica B. Norton, Michele A. Promo, Michele A. Melton, Mark A. Massa, Emily J. Reinhard, Brian S. Hickory, William F. Vernier, Mark E. Smith, Yvette M. Fobian, Karen Regina, Bryan J. Witherbee, Daniel T. Connolly
Publikováno v:
Journal of Medicinal Chemistry. 46:2152-2168
A novel series of substituted N-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]-N-(3-phenoxyphenyl)-trifluoro-3-amino-2-propanols is described which potently and reversibly inhibit cholesteryl ester transfer protein (CETP). Starting from the initial lead 1, va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b10e457203bbb1110208e3911dfa6aac
https://doi.org/10.1021/jm020528+
https://doi.org/10.1021/jm020528+
Autor:
Michele A. Promo, Thomas R. Hoye
Publikováno v:
Tetrahedron Letters. 40:1429-1432
The title process can be used to couple allylic, homoallylic, and bishomoallylic alkenols. Cyclic silaketals with ring sizes from 7–11 members can all be formed. This constitutes a general and versatile strategy for approximately doubling the molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b87a63d2e2068218036881d656c0c513
https://doi.org/10.1016/s0040-4039(98)02697-5
https://doi.org/10.1016/s0040-4039(98)02697-5
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89c4199e5d6b0b7090aa0c6c29fdc7ac
https://doi.org/10.1002/chin.199212179
https://doi.org/10.1002/chin.199212179
Autor:
Michele A. Promo, Thomas R. Hoye
Publikováno v:
ChemInform. 30
The title process can be used to couple allylic, homoallylic, and bishomoallylic alkenols. Cyclic silaketals with ring sizes from 7–11 members can all be formed. This constitutes a general and versatile strategy for approximately doubling the molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5acfb9c147b390a765361db209cd22e8
https://doi.org/10.1002/chin.199919182
https://doi.org/10.1002/chin.199919182
Publikováno v:
The Journal of Organic Chemistry. 56:6188-6199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add63a8f4865b4b784597b9a8210c393
https://doi.org/10.1021/jo00021a043
https://doi.org/10.1021/jo00021a043
Autor:
Emily J, Reinhard, Jane L, Wang, Richard C, Durley, Yvette M, Fobian, Margaret L, Grapperhaus, Brian S, Hickory, Mark A, Massa, Monica B, Norton, Michele A, Promo, Michael B, Tollefson, William F, Vernier, Daniel T, Connolly, Bryan J, Witherbee, Michele A, Melton, Karen J, Regina, Mark E, Smith, James A, Sikorski
Publikováno v:
Journal of medicinal chemistry. 46(11)
A novel series of substituted N-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]-N-(3-phenoxyphenyl)-trifluoro-3-amino-2-propanols is described which potently and reversibly inhibit cholesteryl ester transfer protein (CETP). Starting from the initial lead 1, va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d9119f562ad78addf9a4a9fd8706b8e
https://pubmed.ncbi.nlm.nih.gov/12747787
https://pubmed.ncbi.nlm.nih.gov/12747787