Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Michele, Vacca"'
Autor:
Michele Prisciandaro, Enrico Santinelli, Valeria Tomarchio, Maria Antonietta Tafuri, Cecilia Bonchi, Gloria Palazzo, Carolina Nobile, Alessandra Marinucci, Marcella Mele, Ombretta Annibali, Luigi Rigacci, Michele Vacca
Publikováno v:
Cells, Vol 13, Iss 7, p 586 (2024)
Achieving successful hematopoietic stem cell transplantation (HSCT) relies on two fundamental pillars: effective mobilization and efficient collection through apheresis to attain the optimal graft dose. These cornerstones pave the way for enhanced pa
Externí odkaz:
https://doaj.org/article/a4bc0d5179464148bc93899b82f704cc
Autor:
Antonio Moffa, Domiziana Nardelli, Lucrezia Giorgi, Simone Di Giovanni, Luca Carnuccio, Carmen Mangino, Peter Baptista, Michele Vacca, Manuele Casale
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 3, p 782 (2024)
Background: With promising outcomes, platelet-rich plasma (PRP) has recently been suggested as a treatment for olfactory dysfunction (OD). Methods: Clinical studies utilizing PRP in OD caused by COVID-19, trauma, anesthetic exposure, viral infection,
Externí odkaz:
https://doaj.org/article/546b9774ed814723b140691e3fdefe5c
Autor:
Gabriele Mocciaro, Michael Allison, Benjamin Jenkins, Vian Azzu, Isabel Huang-Doran, Luis Vicente Herrera-Marcos, Zoe Hall, Antonio Murgia, Davies Susan, Mattia Frontini, Antonio Vidal-Puig, Albert Koulman, Julian L. Griffin, Michele Vacca
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101728- (2023)
Background and objectives: Non-alcoholic fatty liver disease (NAFLD) develops due to impaired hepatic lipid fluxes and is a risk factor for chronic liver disease and atherosclerosis. Lipidomic studies consistently reported characteristic hepatic/VLDL
Externí odkaz:
https://doaj.org/article/96005844129c40cea5356a2f95c916ab
Autor:
Ben D. McNally, Dean F. Ashley, Lea Hänschke, Hélène N. Daou, Nicole T. Watt, Steven A. Murfitt, Amanda D. V. MacCannell, Anna Whitehead, T. Scott Bowen, Francis W. B. Sanders, Michele Vacca, Klaus K. Witte, Graeme R. Davies, Reinhard Bauer, Julian L. Griffin, Lee D. Roberts
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Endoplasmic Reticulum stress induces cell non-autonomous Unfolded Protein Response (UPR) activation. Here the authors show that long-chain ceramides are secreted from muscle cells in extracellular vesicles and induce cell non-autonomous UPR activatio
Externí odkaz:
https://doaj.org/article/e431ba3360bc41d78c30c04a825835be
Autor:
Germán Belenguer, Gianmarco Mastrogiovanni, Clare Pacini, Zoe Hall, Anna M. Dowbaj, Robert Arnes-Benito, Aleksandra Sljukic, Nicole Prior, Sofia Kakava, Charles R. Bradshaw, Susan Davies, Michele Vacca, Kourosh Saeb-Parsy, Bon-Kyoung Koo, Meritxell Huch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The E3 ubiquitin ligases RNF43/ZNRF3 are often mutated in cancer but their precise contribution to liver disease is unknown. Here, the authors show that RNF43/ZNRF3 alterations predispose to liver cancer by controlling the differentiation and lipid m
Externí odkaz:
https://doaj.org/article/b340f59562d343c38a3ffe78a2def2d3
Autor:
Katherine Johnson, Peter J. Leary, Olivier Govaere, Matthew J. Barter, Sarah H. Charlton, Simon J. Cockell, Dina Tiniakos, Michalina Zatorska, Pierre Bedossa, M. Julia Brosnan, Jeremy F. Cobbold, Mattias Ekstedt, Guruprasad P. Aithal, Karine Clément, Jörn M. Schattenberg, Jerome Boursier, Vlad Ratziu, Elisabetta Bugianesi, Quentin M. Anstee, Ann K. Daly, James Clark, Heather J. Cordell, Rebecca Darlay, Christopher P. Day, Tim Hardy, Yang-Lin Liu, Fiona Oakley, Jeremy Palmer, Rachel Queen, Kristy Wonders, Patrick M. Bossuyt, Adriaan G. Holleboom, Hadi Zafarmand, Yasaman Vali, Jenny Lee, Karine Clement, Raluca Pais, Detlef Schuppan, Michael Allison, Sergio Rodriguez Cuenca, Vanessa Pellegrinelli, Michele Vacca, Antonio Vidal-Puig, Tuulia Hyötyläinen, Aidan McGlinchey, Matej Orešič, Partho Sen, Jose Mato, Óscar Millet, Jean-Francois Dufour, Stephen Harrison, Stefan Neubauer, Michael Pavlides, Ferenc Mozes, Salma Akhtar, Rajarshi Banerjee, Matt Kelly, Elizabeth Shumbayawonda, Andrea Dennis, Charlotte Erpicum, Manuel Romero-Gomez, Rocío Gallego-Durán, Isabel Fernández, Morten Karsdal, Diana Leeming, Mette Juul Fisker, Elisabeth Erhardtsen, Daniel Rasmussen, Per Qvist, Antonia Sinisi, Estelle Sandt, Maria Manuela Tonini, Maurizio Parola, Chiara Rosso, Fabio Marra, Amalia Gastaldelli, Sven Francque, Stergios Kechagias, Hannele Yki-Järvinen, Kimmo Porthan, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Luca Valenti, Salvatore Petta, Luca Miele, Andreas Geier, Christian Trautwein, Paul Hockings, Phil Newsome, David Wenn, Cecília Maria Pereira Rodrigues, Rémy Hanf, Pierre Chaumat, Christian Rosenquist, Aldo Trylesinski, Pablo Ortiz, Kevin Duffin, Carla Yunis, Melissa Miller, Theresa Tuthill, Judith Ertle, Ramy Younes, Leigh Alexander, Rachel Ostroff, Mette Skalshøi Kjær, Lars Friis Mikkelsen, Clifford Brass, Lori Jennings, Maria-Magdalena Balp, Miljen Martic, Guido Hanauer, Sudha Shankar, Richard Torstenson, Céline Fournier, Richard Ehman, Michael Kalutkiewicz, Kay Pepin, Joel Myers, Diane Shevell, Gideon Ho, Henrik Landgren, Rob Myers, Lynda Doward, Diane Whalley, James Twiss
Publikováno v:
JHEP Reports, Vol 4, Iss 2, Pp 100409- (2022)
Background & Aims: Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods: We profiled 2,083 s
Externí odkaz:
https://doaj.org/article/bf7c90fd285b4e33a8d02523458d147c
Autor:
Vian Azzu, Michele Vacca, Ioannis Kamzolas, Zoe Hall, Jack Leslie, Stefania Carobbio, Samuel Virtue, Susan E. Davies, Agnes Lukasik, Martin Dale, Mohammad Bohlooly-Y, Animesh Acharjee, Daniel Lindén, Guillaume Bidault, Evangelia Petsalaki, Julian L. Griffin, Fiona Oakley, Michael E.D. Allison, Antonio Vidal-Puig
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101210- (2021)
Objective: Non-alcoholic fatty liver disease (NAFLD) is a silent pandemic associated with obesity and the metabolic syndrome, and also increases cardiovascular- and cirrhosis-related morbidity and mortality. A complete understanding of adaptive compe
Externí odkaz:
https://doaj.org/article/e22a0520a7ea4213a3c9346e79e25390
Autor:
Gabriele Mocciaro, Simona D’Amore, Benjamin Jenkins, Richard Kay, Antonio Murgia, Luis Vicente Herrera-Marcos, Stefanie Neun, Alice P. Sowton, Zoe Hall, Susana Alejandra Palma-Duran, Giuseppe Palasciano, Frank Reimann, Andrew Murray, Patrizia Suppressa, Carlo Sabbà, Antonio Moschetta, Albert Koulman, Julian L. Griffin, Michele Vacca
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6786 (2022)
The metabolic syndrome (MetS) is a cluster of cardiovascular risk factors characterised by central obesity, atherogenic dyslipidaemia, and changes in the circulating lipidome; the underlying mechanisms that lead to this lipid remodelling have only be
Externí odkaz:
https://doaj.org/article/c7a8e7e801064758bad28a76a56fec6b
Autor:
Annalisa Contursi, Maria Arconzo, Marica Cariello, Marilidia Piglionica, Simona D'Amore, Michele Vacca, Giusi Graziano, Raffaella Maria Gadaleta, Rosa Valanzano, Renato Mariani-Costantini, Gaetano Villani, Antonio Moschetta, Elena Piccinin
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249238 (2021)
The crypt-villus axis represents the essential unit of the small intestine, which integrity and functions are fundamental to assure tissue and whole-body homeostasis. Disruption of pathways regulating the fine balance between proliferation and differ
Externí odkaz:
https://doaj.org/article/8a3f19433b314cd3b7da2d3398dbaeb7
Autor:
Michele Petruzzelli, Miriam Ferrer, Martijn J. Schuijs, Sam O. Kleeman, Nicholas Mourikis, Zoe Hall, David Perera, Shwethaa Raghunathan, Michele Vacca, Edoardo Gaude, Michael J. Lukey, Duncan I. Jodrell, Christian Frezza, Erwin F. Wagner, Ashok R. Venkitaraman, Timotheus Y. F. Halim, Tobias Janowitz
Publikováno v:
Cancers, Vol 14, Iss 4, p 963 (2022)
An elevated neutrophil–lymphocyte ratio negatively predicts the outcome of patients with cancer and is associated with cachexia, the terminal wasting syndrome. Here, using murine model systems of colorectal and pancreatic cancer we show that neutro
Externí odkaz:
https://doaj.org/article/7f4567f3741343deb91668ec9f55d942